AMN and STAMBP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AMN	STAMBP
Description		amnion associated transmembrane protein	STAM binding protein
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Clathrin-coated Pit Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Endocytic Vesicle Brush Border Membrane Protein-containing Complex Extracellular Exosome	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Isopeptidase Activity
	Biological Process	Receptor-mediated Endocytosis Multicellular Organism Development Excretion Protein Localization Cobalamin Metabolic Process Cobalamin Transport High-density Lipoprotein Particle Clearance Golgi To Plasma Membrane Protein Transport	Mitotic Cytokinesis Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism Defective AMN causes hereditary megaloblastic anemia 1 Defective CUBN causes hereditary megaloblastic anemia 1 HDL clearance	Metalloprotease DUBs
Drugs		Hydroxocobalamin
Diseases
GWAS		Body mass index ( 26426971)	Anti-saccade response ( 29064472) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944)
Interacting Genes		1 interacting genes: STAMBP	45 interacting genes: ALAS1 AMN APOBEC3A BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP3 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28
Entrez ID		81693	10617
HPRD ID		09314	05877
Ensembl ID		ENSG00000166126	ENSG00000124356
Uniprot IDs		B3KP64 Q9BXJ7	A0A140VK54 O95630
PDB IDs		6GJE	2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?
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