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NDEL1 and AKAP9
Data Source:
BioGRID
(two hybrid)
NDEL1
AKAP9
Description
nudE neurodevelopment protein 1 like 1
A-kinase anchoring protein 9
Image
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Nuclear Envelope
Centrosome
Spindle
Cytosol
Kinesin Complex
Microtubule
Synaptic Vesicle
Cell Leading Edge
Axon Hillock
Neurofilament Cytoskeleton
Central Region Of Growth Cone
Axon Cytoplasm
Golgi Apparatus
Golgi Stack
Cis-Golgi Network
Centrosome
Cytosol
Cytoskeleton
Voltage-gated Potassium Channel Complex
Intracellular Membrane-bounded Organelle
Synaptic Membrane
Glutamatergic Synapse
Molecular Function
Protein Binding
Microtubule Binding
Identical Protein Binding
Alpha-tubulin Binding
Protein-containing Complex Binding
Beta-tubulin Binding
Oligopeptidase Activity
DNA Binding
Signaling Receptor Binding
Protein Binding
Potassium Channel Regulator Activity
Protein Kinase A Regulatory Subunit Binding
Ion Channel Binding
Molecular Adaptor Activity
Biological Process
Establishment Of Mitotic Spindle Orientation
Neuron Migration
Inner Cell Mass Cell Proliferation
Proteolysis
Microtubule Nucleation
Chromosome Segregation
Mitotic Centrosome Separation
Retrograde Axonal Transport
Insulin Receptor Signaling Pathway
Regulation Of Neuron Projection Development
Cell Migration
Cerebral Cortex Radially Oriented Cell Migration
Central Nervous System Neuron Axonogenesis
Lysosome Localization
Regulation Of Intracellular Protein Transport
Positive Regulation Of GTPase Activity
Positive Regulation Of Axon Extension
Vesicle Transport Along Microtubule
Positive Regulation Of Axon Regeneration
Nuclear Envelope Disassembly
Establishment Of Chromosome Localization
Centrosome Localization
Neurofilament Cytoskeleton Organization
Activation Of GTPase Activity
Positive Regulation Of Ruffle Assembly
Neuron Projection Extension
Regulation Of Microtubule Motor Activity
G2/M Transition Of Mitotic Cell Cycle
Microtubule Nucleation
Signal Transduction
Chemical Synaptic Transmission
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Microtubule Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Maintenance Of Centrosome Location
Regulation Of Membrane Repolarization
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Cardiac Conduction
Cellular Response To CAMP
Regulation Of Heart Rate By Cardiac Conduction
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Golgi Organization
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Phase 3 - rapid repolarisation
Phase 2 - plateau phase
Anchoring of the basal body to the plasma membrane
Signaling by BRAF and RAF fusions
AURKA Activation by TPX2
Drugs
Diseases
Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) (
24236485
)
Breast cancer (
29059683
)
Cerebrospinal fluid p-tau levels in mild cognitive impairment (
29274321
)
Cerebrospinal fluid t-tau levels in mild cognitive impairment (
29274321
)
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) (
30120083
)
Hippocampal volume in Alzheimer's disease dementia (
29274321
)
Red blood cell count (
32888494
)
Interacting Genes
88 interacting genes:
ABI3
ACTB
AIMP2
AKAP9
ANK2
APP
BMI1
BORCS6
BRK1
CASK
CCDC88A
CCSER1
CDK5
CENPF
CEP170
CEP55
CEP63
CWF19L2
DISC1
DIXDC1
DTNB
DYNC1H1
DYNC1I1
DYNLL1
FXR2
GOLGA2
IMMT
KALRN
KIF19
KIF2C
KIF5A
KIFC3
KLC4
KRT40
LUC7L2
MAGEA11
MBIP
MED11
MIS18A
MLLT10
MRC2
MTUS2
MYO5A
NDC80
PAFAH1B1
PARD6G
PARVG
PICK1
PKP2
PRC1
RBM10
RBM14
RBM5
RPA2
SLAIN1
SNAPC5
SNX6
SYNE1
TACC3
TRAF3IP3
TRIM27
TUBB
USP2
XPA
YWHAE
YWHAG
ZC2HC1C
ZNF10
ZNF12
ZNF17
ZNF180
ZNF197
ZNF211
ZNF230
ZNF250
ZNF260
ZNF264
ZNF3
ZNF35
ZNF417
ZNF490
ZNF544
ZNF572
ZNF599
ZNF662
ZNF707
ZNF844
ZNF91
85 interacting genes:
ABI2
BEX2
BLZF1
C1orf94
CALM1
CALM2
CALM3
CASK
CCDC116
CCDC146
CCP110
CDC5L
CEP55
CLIC1
CSNK1D
CSNK1E
CTBP1
CTNNA3
DVL2
FAM90A1
FMR1
FNBP1
FXR2
GLIS2
GPC4
GRIN1
GTSE1
HDDC3
HNRNPM
IKZF3
KCNQ1
KDM1A
KIF19
KLC4
LMO1
MAGEA6
MAGED1
MED1
MYO5A
NDEL1
PARD6G
PCM1
PCNT
PKN1
PKP2
PPP1CA
PPP2R1B
PPP2R3A
PRC1
PRDM14
PRKAR2A
PRKAR2B
PRKCE
RBM10
RBM14
RPA2
RSRC2
SAMD3
SCNM1
SF3B2
SLAIN1
SNF8
SNRPB
SSX2
SSX3
SSX5
SUV39H2
TACC3
TCEANC
TDP2
TENT5B
THAP1
THOC1
TLX3
TNIK
TRIP10
TSG101
TSNAX
TUBGCP3
TULP3
USHBP1
USO1
VPS9D1
WAC
YWHAE
Entrez ID
81565
10142
HPRD ID
06340
04921
Ensembl ID
ENSG00000166579
ENSG00000127914
Uniprot IDs
A6NIZ0
Q9GZM8
Q5GIA7
Q6PJH3
Q99996
PDB IDs
2V66
Enriched GO Terms of Interacting Partners
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