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NDEL1 and BMI1
Data Source:
BioGRID
(two hybrid)
NDEL1
BMI1
Description
nudE neurodevelopment protein 1 like 1
BMI1 proto-oncogene, polycomb ring finger
Image
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Nuclear Envelope
Centrosome
Spindle
Cytosol
Kinesin Complex
Microtubule
Synaptic Vesicle
Cell Leading Edge
Axon Hillock
Neurofilament Cytoskeleton
Central Region Of Growth Cone
Axon Cytoplasm
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytosol
Nuclear Body
PcG Protein Complex
PRC1 Complex
Molecular Function
Protein Binding
Microtubule Binding
Identical Protein Binding
Alpha-tubulin Binding
Protein-containing Complex Binding
Beta-tubulin Binding
Oligopeptidase Activity
Protein Binding
Zinc Ion Binding
RING-like Zinc Finger Domain Binding
Promoter-specific Chromatin Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Neuron Migration
Inner Cell Mass Cell Proliferation
Proteolysis
Microtubule Nucleation
Chromosome Segregation
Mitotic Centrosome Separation
Retrograde Axonal Transport
Insulin Receptor Signaling Pathway
Regulation Of Neuron Projection Development
Cell Migration
Cerebral Cortex Radially Oriented Cell Migration
Central Nervous System Neuron Axonogenesis
Lysosome Localization
Regulation Of Intracellular Protein Transport
Positive Regulation Of GTPase Activity
Positive Regulation Of Axon Extension
Vesicle Transport Along Microtubule
Positive Regulation Of Axon Regeneration
Nuclear Envelope Disassembly
Establishment Of Chromosome Localization
Centrosome Localization
Neurofilament Cytoskeleton Organization
Activation Of GTPase Activity
Positive Regulation Of Ruffle Assembly
Neuron Projection Extension
Regulation Of Microtubule Motor Activity
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Segment Specification
Regulation Of Gene Expression
Hemopoiesis
Histone H2A-K119 Monoubiquitination
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of G0 To G1 Transition
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
Drugs
Diseases
Penile cancer
GWAS
Prostate-specific antigen levels (
28139693
)
Interacting Genes
88 interacting genes:
ABI3
ACTB
AIMP2
AKAP9
ANK2
APP
BMI1
BORCS6
BRK1
CASK
CCDC88A
CCSER1
CDK5
CENPF
CEP170
CEP55
CEP63
CWF19L2
DISC1
DIXDC1
DTNB
DYNC1H1
DYNC1I1
DYNLL1
FXR2
GOLGA2
IMMT
KALRN
KIF19
KIF2C
KIF5A
KIFC3
KLC4
KRT40
LUC7L2
MAGEA11
MBIP
MED11
MIS18A
MLLT10
MRC2
MTUS2
MYO5A
NDC80
PAFAH1B1
PARD6G
PARVG
PICK1
PKP2
PRC1
RBM10
RBM14
RBM5
RPA2
SLAIN1
SNAPC5
SNX6
SYNE1
TACC3
TRAF3IP3
TRIM27
TUBB
USP2
XPA
YWHAE
YWHAG
ZC2HC1C
ZNF10
ZNF12
ZNF17
ZNF180
ZNF197
ZNF211
ZNF230
ZNF250
ZNF260
ZNF264
ZNF3
ZNF35
ZNF417
ZNF490
ZNF544
ZNF572
ZNF599
ZNF662
ZNF707
ZNF844
ZNF91
42 interacting genes:
CASC9
CBX8
CEP126
CSNK2B
E2F6
FOXS1
H2AC18
H2AC20
H2AC4
H2AX
H3-4
HSF2BP
IMMT
KAT5
KMT2A
LRIF1
MAPK14
MLLT1
MUC1
NDEL1
PCBP2-OT1
PCGF3
PCGF6
PGR
PHC1
PHC2
PTN
RING1
RNF114
RNF2
RRM1
SOCS2
TRIM27
TUSC3
UBE2D2
UBE2D3
UBE2I
USP11
USP15
VPS11
WHRN
ZBTB16
Entrez ID
81565
648
HPRD ID
06340
01277
Ensembl ID
ENSG00000166579
ENSG00000168283
Uniprot IDs
A6NIZ0
Q9GZM8
P35226
PDB IDs
2V66
2H0D
2NA1
3RPG
4R8P
5FR6
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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