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NDEL1 and ZNF599
Data Source:
BioGRID
(two hybrid)
NDEL1
ZNF599
Description
nudE neurodevelopment protein 1 like 1
zinc finger protein 599
Image
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Nuclear Envelope
Centrosome
Spindle
Cytosol
Kinesin Complex
Microtubule
Synaptic Vesicle
Cell Leading Edge
Axon Hillock
Neurofilament Cytoskeleton
Central Region Of Growth Cone
Axon Cytoplasm
Nucleus
Molecular Function
Protein Binding
Microtubule Binding
Identical Protein Binding
Alpha-tubulin Binding
Protein-containing Complex Binding
Beta-tubulin Binding
Oligopeptidase Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Neuron Migration
Inner Cell Mass Cell Proliferation
Proteolysis
Microtubule Nucleation
Chromosome Segregation
Mitotic Centrosome Separation
Retrograde Axonal Transport
Insulin Receptor Signaling Pathway
Regulation Of Neuron Projection Development
Cell Migration
Cerebral Cortex Radially Oriented Cell Migration
Central Nervous System Neuron Axonogenesis
Lysosome Localization
Regulation Of Intracellular Protein Transport
Positive Regulation Of GTPase Activity
Positive Regulation Of Axon Extension
Vesicle Transport Along Microtubule
Positive Regulation Of Axon Regeneration
Nuclear Envelope Disassembly
Establishment Of Chromosome Localization
Centrosome Localization
Neurofilament Cytoskeleton Organization
Activation Of GTPase Activity
Positive Regulation Of Ruffle Assembly
Neuron Projection Extension
Regulation Of Microtubule Motor Activity
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Generic Transcription Pathway
Drugs
Diseases
GWAS
Alzheimer disease and age of onset (
26830138
)
Hippocampal volume in Alzheimer's disease dementia (
29274321
)
Long-term memory (delayed word recall task) (
29970928
)
Urate levels (BMI interaction) (
25811787
)
Interacting Genes
88 interacting genes:
ABI3
ACTB
AIMP2
AKAP9
ANK2
APP
BMI1
BORCS6
BRK1
CASK
CCDC88A
CCSER1
CDK5
CENPF
CEP170
CEP55
CEP63
CWF19L2
DISC1
DIXDC1
DTNB
DYNC1H1
DYNC1I1
DYNLL1
FXR2
GOLGA2
IMMT
KALRN
KIF19
KIF2C
KIF5A
KIFC3
KLC4
KRT40
LUC7L2
MAGEA11
MBIP
MED11
MIS18A
MLLT10
MRC2
MTUS2
MYO5A
NDC80
PAFAH1B1
PARD6G
PARVG
PICK1
PKP2
PRC1
RBM10
RBM14
RBM5
RPA2
SLAIN1
SNAPC5
SNX6
SYNE1
TACC3
TRAF3IP3
TRIM27
TUBB
USP2
XPA
YWHAE
YWHAG
ZC2HC1C
ZNF10
ZNF12
ZNF17
ZNF180
ZNF197
ZNF211
ZNF230
ZNF250
ZNF260
ZNF264
ZNF3
ZNF35
ZNF417
ZNF490
ZNF544
ZNF572
ZNF599
ZNF662
ZNF707
ZNF844
ZNF91
9 interacting genes:
CCDC136
CEP70
CMTM5
GOLGA6L9
KRTAP10-9
MTUS2
NDEL1
TSGA10
ZRANB1
Entrez ID
81565
148103
HPRD ID
06340
18355
Ensembl ID
ENSG00000166579
ENSG00000153896
Uniprot IDs
A6NIZ0
Q9GZM8
Q96NL3
PDB IDs
2V66
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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