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AKAP9 and TSG101
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
AKAP9
TSG101
Description
A-kinase anchoring protein 9
tumor susceptibility 101
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Golgi Stack
Cis-Golgi Network
Centrosome
Cytosol
Cytoskeleton
Voltage-gated Potassium Channel Complex
Intracellular Membrane-bounded Organelle
Synaptic Membrane
Glutamatergic Synapse
ESCRT I Complex
Nucleolus
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Microtubule Organizing Center
Cytosol
Plasma Membrane
Endosome Membrane
Early Endosome Membrane
Late Endosome Membrane
Host Cell
Extracellular Exosome
Flemming Body
Molecular Function
DNA Binding
Signaling Receptor Binding
Protein Binding
Potassium Channel Regulator Activity
Protein Kinase A Regulatory Subunit Binding
Ion Channel Binding
Molecular Adaptor Activity
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Coactivator Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Binding
Protein-containing Complex Binding
Virion Binding
Calcium-dependent Protein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Microtubule Nucleation
Signal Transduction
Chemical Synaptic Transmission
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Microtubule Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Maintenance Of Centrosome Location
Regulation Of Membrane Repolarization
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Cardiac Conduction
Cellular Response To CAMP
Regulation Of Heart Rate By Cardiac Conduction
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Golgi Organization
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Protein Monoubiquitination
Extracellular Transport
Cell Cycle Arrest
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Keratinocyte Differentiation
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of MAP Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Viral Budding
Cell Division
Intracellular Transport Of Virus
Autophagosome Maturation
Regulation Of Viral Release From Host Cell
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Exosomal Secretion
Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Phase 3 - rapid repolarisation
Phase 2 - plateau phase
Anchoring of the basal body to the plasma membrane
Signaling by BRAF and RAF fusions
AURKA Activation by TPX2
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Drugs
Diseases
Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) (
24236485
)
Breast cancer (
29059683
)
Cerebrospinal fluid p-tau levels in mild cognitive impairment (
29274321
)
Cerebrospinal fluid t-tau levels in mild cognitive impairment (
29274321
)
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) (
30120083
)
Hippocampal volume in Alzheimer's disease dementia (
29274321
)
Red blood cell count (
32888494
)
Interacting Genes
85 interacting genes:
ABI2
BEX2
BLZF1
C1orf94
CALM1
CALM2
CALM3
CASK
CCDC116
CCDC146
CCP110
CDC5L
CEP55
CLIC1
CSNK1D
CSNK1E
CTBP1
CTNNA3
DVL2
FAM90A1
FMR1
FNBP1
FXR2
GLIS2
GPC4
GRIN1
GTSE1
HDDC3
HNRNPM
IKZF3
KCNQ1
KDM1A
KIF19
KLC4
LMO1
MAGEA6
MAGED1
MED1
MYO5A
NDEL1
PARD6G
PCM1
PCNT
PKN1
PKP2
PPP1CA
PPP2R1B
PPP2R3A
PRC1
PRDM14
PRKAR2A
PRKAR2B
PRKCE
RBM10
RBM14
RPA2
RSRC2
SAMD3
SCNM1
SF3B2
SLAIN1
SNF8
SNRPB
SSX2
SSX3
SSX5
SUV39H2
TACC3
TCEANC
TDP2
TENT5B
THAP1
THOC1
TLX3
TNIK
TRIP10
TSG101
TSNAX
TUBGCP3
TULP3
USHBP1
USO1
VPS9D1
WAC
YWHAE
120 interacting genes:
AATF
ADRB2
AJUBA
AKAP9
AR
ARRDC1
BAG4
BCAS3
BCR
BIRC2
CAGE1
CBY1
CCDC88B
CCHCR1
CCND3
CDKN1A
CDKN2D
CDS2
CEP55
CEP63
CNOT7
DAXX
DMAP1
DMRTB1
DNMT1
DZIP3
EP300
FAM110A
FAM9B
GGA1
GGA3
GMCL1
GOLM1
HAUS1
HCK
HGS
HSH2D
INCA1
IQGAP1
ITSN1
JUN
KIAA1328
KIF5A
KIFC3
KLK5
KLK6
KRT13
KRT15
KRT16
KRT18
KRT31
KRT34
KRT35
KRT75
LCN2
LENG8
LNX1
LRSAM1
MDM2
MGRN1
MKRN3
MTA3
MZB1
NR3C1
PDCD6IP
PDLIM7
PIAS1
PKNOX2
PPFIBP2
PPP1R13B
PRDM16
PRSS50
QKI
RAD18
RASL10B
RBPMS
RNF111
RNF126
RNF41
ROCK1
SCAMP3
SCARA5
SCGB3A1
SCNN1A
SH3GLB2
SNAPIN
SNF8
SNX32
STK11
SYCE1
TAX1BP1
TEX11
TFF1
TFIP11
THRB
THRSP
TNIP1
TNIP2
TNNT3
TOM1L1
TP53
TRAIP
TRIM23
TRIM35
TRIM46
TRIM54
TRIM74
TRIML2
UBA52
UBC
USHBP1
VPS11
VPS28
VPS36
VPS37A
VPS37B
VPS37C
VPS37D
WASHC1
ZWINT
Entrez ID
10142
7251
HPRD ID
04921
03229
Ensembl ID
ENSG00000127914
ENSG00000074319
Uniprot IDs
Q5GIA7
Q6PJH3
Q99996
Q99816
PDB IDs
1KPP
1KPQ
1M4P
1M4Q
1S1Q
2F0R
3IV1
3OBQ
3OBS
3OBU
3OBX
3P9G
3P9H
4EJE
4YC1
4ZNY
5VKG
6VME
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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