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LHX3 and FAIM
Data Source:
BioGRID
(two hybrid)
LHX3
FAIM
Description
LIM homeobox 3
Fas apoptotic inhibitory molecule
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Transcription Regulator Complex
Cytoplasm
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Sequence-specific DNA Binding
Metal Ion Binding
Protein Binding
Biological Process
Placenta Development
Regulation Of Transcription By RNA Polymerase II
Motor Neuron Axon Guidance
Animal Organ Morphogenesis
Spinal Cord Motor Neuron Cell Fate Specification
Ventral Spinal Cord Interneuron Specification
Medial Motor Column Neuron Differentiation
Spinal Cord Association Neuron Differentiation
Pituitary Gland Development
Neuron Differentiation
Lung Development
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Inner Ear Development
Apoptotic Process
I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Neurogenesis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Regulation of expression of SLITs and ROBOs
Drugs
Diseases
Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Atrial fibrillation (
30061737
)
Crohn's disease (
28067908
)
Free thyroxine concentration (
25743335
)
Height (
28552196
20189936
)
Inflammatory bowel disease (
28067908
)
Lung function (FEV1) (
26635082
)
Lung function (FVC) (
28166213
26635082
)
Mean corpuscular volume (
32888494
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Thyroid hormone levels (
23408906
)
Ulcerative colitis (
28067908
)
Blood protein levels (
30072576
)
Male-pattern baldness (
28196072
)
Interacting Genes
78 interacting genes:
ABI2
ACTN3
AIF1L
ANKRD45
ANP32A
ATP6V1G1
BYSL
C2CD6
CCDC146
CCDC6
CDC23
CDK3
CITED2
CKS1B
CLCNKA
CPNE7
CSNK2A1
CWF19L2
ENKD1
FAIM
FAM124B
FAM221A
FIGLA
GAS2L2
GAS8
GCM2
GUCD1
HOXC5
HOXC8
IFT172
INCA1
INSC
INTS4
IQUB
ISL1
ISL2
KANK2
KLHL38
KRT3
LDB1
LHX1
LMX1A
MAPK9
NFKBID
NRDE2
NRF1
NUDT22
OCRL
PARP11
PARVG
PNMA5
PRKAB2
PSMB1
PSORS1C2
QRICH1
RCOR3
RHBDF1
RLIM
RUNX1T1
SAT1
SCNM1
SH2D1A
SNRNP25
TAF1
TCEANC
TEX14
TLE5
TSEN54
TSSK3
UBTFL1
USP2
VEZF1
YY1
ZNF354C
ZNF417
ZNF574
ZNF587
ZNF76
9 interacting genes:
CDR2L
DAPP1
INCA1
LHX3
LMNA
SPRY2
TRIM62
ZNF16
ZRANB1
Entrez ID
8022
55179
HPRD ID
02783
16874
Ensembl ID
ENSG00000107187
ENSG00000158234
Uniprot IDs
F1T0D5
F1T0D9
Q9UBR4
Q9NVQ4
PDB IDs
2KW1
3MX7
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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