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LHX3 and ENKD1
Data Source:
BioGRID
(two hybrid)
LHX3
ENKD1
Description
LIM homeobox 3
enkurin domain containing 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Transcription Regulator Complex
Cytoplasmic Microtubule
Microtubule Cytoskeleton
Ciliary Base
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Sequence-specific DNA Binding
Metal Ion Binding
Protein Binding
Biological Process
Placenta Development
Regulation Of Transcription By RNA Polymerase II
Motor Neuron Axon Guidance
Animal Organ Morphogenesis
Spinal Cord Motor Neuron Cell Fate Specification
Ventral Spinal Cord Interneuron Specification
Medial Motor Column Neuron Differentiation
Spinal Cord Association Neuron Differentiation
Pituitary Gland Development
Neuron Differentiation
Lung Development
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Inner Ear Development
Pathways
Regulation of expression of SLITs and ROBOs
Drugs
Diseases
Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Atrial fibrillation (
30061737
)
Crohn's disease (
28067908
)
Free thyroxine concentration (
25743335
)
Height (
28552196
20189936
)
Inflammatory bowel disease (
28067908
)
Lung function (FEV1) (
26635082
)
Lung function (FVC) (
28166213
26635082
)
Mean corpuscular volume (
32888494
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Thyroid hormone levels (
23408906
)
Ulcerative colitis (
28067908
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
78 interacting genes:
ABI2
ACTN3
AIF1L
ANKRD45
ANP32A
ATP6V1G1
BYSL
C2CD6
CCDC146
CCDC6
CDC23
CDK3
CITED2
CKS1B
CLCNKA
CPNE7
CSNK2A1
CWF19L2
ENKD1
FAIM
FAM124B
FAM221A
FIGLA
GAS2L2
GAS8
GCM2
GUCD1
HOXC5
HOXC8
IFT172
INCA1
INSC
INTS4
IQUB
ISL1
ISL2
KANK2
KLHL38
KRT3
LDB1
LHX1
LMX1A
MAPK9
NFKBID
NRDE2
NRF1
NUDT22
OCRL
PARP11
PARVG
PNMA5
PRKAB2
PSMB1
PSORS1C2
QRICH1
RCOR3
RHBDF1
RLIM
RUNX1T1
SAT1
SCNM1
SH2D1A
SNRNP25
TAF1
TCEANC
TEX14
TLE5
TSEN54
TSSK3
UBTFL1
USP2
VEZF1
YY1
ZNF354C
ZNF417
ZNF574
ZNF587
ZNF76
207 interacting genes:
ABI1
ABI2
ACOT7
AKAP8L
ANKRD23
ANKRD49
APP
ARMC5
ASB3
AVPI1
BANP
BCAS2
BCAS4
BCAT1
BEGAIN
BEX3
BHLHB9
BLZF1
BRAT1
C18orf54
C19orf54
C1orf105
CALCOCO1
CALCOCO2
CBY1
CBY2
CCDC102B
CCDC13
CCDC136
CCDC28B
CCDC85B
CDCA4
CDPF1
CDR2
CDSN
CEP55
CEP70
CHCHD3
CHRDL2
COA7
CTBP2
CYSRT1
DGCR6
DVL2
DVL3
DYDC1
ECM1
EFHC2
EIF4G1
EYA2
EZHIP
FAM102A
FAM228A
FAM90A1
FCHSD2
FKBP6
FOS
FOSB
FSD2
GADD45G
GADD45GIP1
GET4
GFAP
GIGYF1
GOLGA2
GOLGA6A
GOLGA6L9
GRHL3
GRIPAP1
HMBOX1
HNRNPH1
HOMEZ
HOOK2
HOXA1
HSF2BP
HSPB2
HSPB2-C11orf52
ID2
IGF1
IGFBP6
IKBKG
IKZF3
JAKMIP1
KIFC3
KLHL20
KLHL26
KRT14
KRT15
KRT31
KRT35
KRT40
KRTAP10-5
KRTAP10-8
KRTAP11-1
KRTAP12-1
KRTAP13-2
KRTAP19-1
KRTAP19-5
KRTAP19-6
KRTAP4-11
KRTAP5-9
KRTAP6-2
LDOC1
LHX3
LIN7B
LMO2
LRRC61
LZTS1
MAPK9
MATN4
MDFI
MEIS3
MESD
METTL27
MID2
MIF4GD
MIPOL1
MISP
MKRN3
MLH1
MORN3
MORN5
MRNIP
MRPL28
MRPL38
MTUS2
MYF5
MYOZ3
N4BP3
NAB2
NBPF22P
NBPF6
NCKIPSD
NDUFB7
NEFL
NFKBIA
NHLRC4
NUTM1
OOEP
PAK5
PDLIM7
PDZD4
PHC2
PIBF1
PICK1
PIK3R3
PKNOX2
PLSCR1
PNMA1
PNMA2
POLR3C
PPP1CC
PPP2R3C
PRDM14
PRDM6
RAD54B
RBCK1
RBM11
RBPMS
RCN1
RUBCN
RUNDC3A
SLC15A2
SNRNP48
SORBS3
SPAG5
SPDEF
SPSB3
SRGAP3
SSC4D
STAC3
STXBP4
TENT5B
TNNI1
TNS2
TOX2
TRAF1
TRAF2
TRAK1
TRGV7
TRIM23
TRIM27
TRIM35
TRIM54
TSC1
TSC22D4
TSEN15
UBXN11
USH1C
USH1G
USHBP1
USP20
VBP1
VPS37B
VWC2
WDR62
WWOX
YWHAE
ZBTB14
ZC2HC1C
ZFP90
ZNF143
ZNF426
ZNF511
ZNF581
ZNF76
ZRANB1
Entrez ID
8022
84080
HPRD ID
02783
13151
Ensembl ID
ENSG00000107187
ENSG00000124074
Uniprot IDs
F1T0D5
F1T0D9
Q9UBR4
Q9H0I2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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