FAIM and TRIM62

Data Source:
BioGRID (two hybrid)

		FAIM	TRIM62
Description		Fas apoptotic inhibitory molecule	tripartite motif containing 62
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Cytosol
	Molecular Function	Protein Binding	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neurogenesis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Male-pattern baldness ( 28196072)	Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		9 interacting genes: CDR2L DAPP1 INCA1 LHX3 LMNA SPRY2 TRIM62 ZNF16 ZRANB1	19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25
Entrez ID		55179	55223
HPRD ID		16874	07697
Ensembl ID		ENSG00000158234	ENSG00000116525
Uniprot IDs		Q9NVQ4	Q9BVG3
PDB IDs		2KW1 3MX7
Enriched GO Terms of Interacting Partners?
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