SAP30L and FEZ1

Data Source:
HPRD (two hybrid, in vitro)

		SAP30L	FEZ1
Description		SAP30 like	fasciculation and elongation protein zeta 1
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Fibrillar Center Nucleoplasm Nucleolus	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Microtubule Plasma Membrane Axon Dendrite Growth Cone Neuronal Cell Body
	Molecular Function	DNA Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Phosphatidylinositol-5-phosphate Binding Nucleosome Binding Histone Binding Non-sequence-specific DNA Binding, Bending	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Positive Regulation Of Neuron Differentiation Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Mitochondrion Morphogenesis Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) QRS duration ( 25035420)	Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		4 interacting genes: DVL3 FEZ1 FEZ2 HMBOX1	57 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		79685	9638
HPRD ID		08563	09212
Ensembl ID		ENSG00000164576	ENSG00000149557
Uniprot IDs		Q9HAJ7	Q99689
PDB IDs		2N1U
Enriched GO Terms of Interacting Partners?
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