SAP30L and HMBOX1

Data Source:
BioGRID (two hybrid)

		SAP30L	HMBOX1
Description		SAP30 like	homeobox containing 1
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GO Annotations	Cellular Component	Histone Deacetylase Complex Fibrillar Center Nucleoplasm Nucleolus	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	DNA Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Phosphatidylinositol-5-phosphate Binding Nucleosome Binding Histone Binding Non-sequence-specific DNA Binding, Bending	Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) QRS duration ( 25035420)	Obesity-related traits ( 23251661)
Interacting Genes		4 interacting genes: DVL3 FEZ1 FEZ2 HMBOX1	100 interacting genes: ABITRAM AEBP2 ANKRD36 APP ASB7 ATP5PO BAZ2B BEND7 BRD1 BYSL C8orf33 CARD9 CBX8 CCDC187 CCNG1 CDC7 CDCA8 CDK18 DAB1 DNTTIP1 DYNLL1 DYNLL2 ENKD1 ENTPD2 FAM13C FAM161A FAM217B FAM74A4 FAM90A1 FARS2 FGF11 FNDC11 FRMD6 FXR2 GAS2L2 GNL3L GSC2 INO80B IPO13 KAT5 KIF9 LMO1 LMO3 LNX1 MAGEH1 MCRS1 MEOX1 MEOX2 MFAP1 MORF4L1 MORF4L2 MRPL11 MRPL28 PAX5 PAX6 PIAS2 PICK1 PIP4K2B PKD1P1 POLDIP3 POLL PRKAA1 PRKAA2 PRPF18 RBMY2FP RCOR3 REEP6 RPL9 RPS25 SAP30L SCNM1 SDCBP SFR1 SH2D4A SNRPB2 SNW1 SYT6 TBP TCEA2 TCEANC TSGA10IP TUFM U2AF2 UBA6 UBE2I UBE2Z VAX1 VPS72 WT1 ZBTB24 ZBTB26 ZFYVE26 ZMAT2 ZMYM5 ZNF250 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		79685	79618
HPRD ID		08563	07964
Ensembl ID		ENSG00000164576	ENSG00000147421
Uniprot IDs		Q9HAJ7	D3DSU2 Q6NT76
PDB IDs		2N1U	2CUF 4J19
Enriched GO Terms of Interacting Partners?
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