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ZNF76 and TBP
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(two hybrid)
ZNF76
TBP
Description
zinc finger protein 76
TATA-box binding protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Chromatin
Euchromatin
Female Pronucleus
Male Pronucleus
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIA Complex
Cytoplasm
Protein-containing Complex
Transcription Preinitiation Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific DNA Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase III General Transcription Initiation Factor Activity
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II General Transcription Initiation Factor Binding
TFIIB-class Transcription Factor Binding
RNA Polymerase II Repressing Transcription Factor Binding
Protein Binding
Transcription Factor Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Aryl Hydrocarbon Receptor Binding
Enzyme Binding
Repressing Transcription Factor Binding
General Transcription Initiation Factor Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase III
Positive Regulation Of Transcription By RNA Polymerase II
DNA-templated Transcription, Initiation
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription By RNA Polymerase III
Spermatogenesis
Viral Process
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
RNA Polymerase II Preinitiation Complex Assembly
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Estrogen-dependent gene expression
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Height (
25282103
31562340
18391951
)
Plateletcrit (
32888494
)
Refractive error (
32231278
)
Type 1 diabetes (
21980299
)
Interacting Genes
93 interacting genes:
ACAT2
ALOXE3
ANKRD37
ANTKMT
ATP5PO
BLZF1
BOLA2
BOLA2B
C10orf55
C22orf15
C3orf36
CCDC33
CEACAM6
CEP76
CSN3
DDIT4L
DISC1
ENKD1
EP300
EXOSC1
FAM228A
FAM90A1
FCRL4
FHL2
FNDC8
FSD2
GIMAP6
GRAPL
HDAC1
HOMEZ
IKZF3
KCTD9
KLF15
KPNA3
KRT40
KRT75
L3MBTL3
LAP3
LETM1
LHX3
LHX4
LHX6
LIN37
LIN54
LMO1
MAGEA6
MBD3L1
MBD5
MED19
MFAP1
MORN3
MRPL12
MTFR1L
MTUS2
MYL10
NEDD9
NRIP2
PIAS1
PMPCA
POGZ
PRKAR1B
RAB3IP
RALY
REL
RNF214
RPRD1A
RPS21
SCNM1
SLAIN1
SMAD1
SNAI2
SPANXN3
SPATA8
STMN3
TASOR2
TBC1D22B
TBP
TEKT5
TEX43
TGS1
TNNI1
USP54
USP6
USP7
VXN
WDR83
YPEL3
ZC2HC1C
ZC4H2
ZMYM6
ZNF420
ZNF526
ZNF623
122 interacting genes:
ABT1
AHR
AR
ATF4
BCL3
BRD2
BRF1
BRF2
BTAF1
CAND2
CITED2
COL26A1
CREG1
CREM
CTBP1
CTCFL
CUEDC2
CXXC1
DHX9
DR1
DRAP1
E2F1
EDF1
ELF3
ESR1
ETS1
FATE1
FOS
FOXF2
GOLGA2
GTF2A1
GTF2A1L
GTF2A2
GTF2B
GTF2E1
GTF2E2
GTF2F1
GTF2F2
GTF2H4
GTF3C2
GTF3C3
GTF3C4
GTF3C5
H3-4
HAP1
HMBOX1
HMGB1
HNF4A
HNRNPK
HSF1
HTT
HUWE1
IKZF1
JUN
JUND
JUP
KDM5A
KLF5
MBD2
MCM2
MDM2
MSX1
MYC
NACA
NCAPH
NCOA1
NCOA3
NCOA6
NFYB
NFYC
NR3C1
PAX3
PAX5
PAX6
PIAS1
PIAS3
POLR2A
POLR3F
POU2F1
POU2F2
POU3F2
PSMC2
PSME3
RB1
REL
RELA
REST
RNF4
RUVBL1
RUVBL2
RXRA
SERPINB5
SNAPC1
SNAPC2
SNAPC4
SP1
SPI1
SPIB
SSX2IP
SUB1
TAF1
TAF10
TAF11
TAF12
TAF13
TAF1A
TAF1B
TAF1C
TAF1L
TAF5
TAF7L
TCF12
TEAD1
TP53
TRAM2
TRIP4
UBE2I
UBTF
WDR62
YEATS2
YWHAE
ZNF76
Entrez ID
7629
6908
HPRD ID
01929
02511
Ensembl ID
ENSG00000065029
ENSG00000112592
Uniprot IDs
A0A024RCU3
A0A024RCW5
P36508
P20226
Q32MN7
PDB IDs
1C9B
1CDW
1JFI
1NVP
1TGH
4ROC
4ROD
4ROE
5FUR
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
5N9G
6MZD
6MZL
6MZM
6O9L
Enriched GO Terms of Interacting Partners
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