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TBP and NCOA3
Data Source:
HPRD
(in vitro)
TBP
NCOA3
Description
TATA-box binding protein
nuclear receptor coactivator 3
Image
GO Annotations
Cellular Component
Chromatin
Euchromatin
Female Pronucleus
Male Pronucleus
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIA Complex
Cytoplasm
Protein-containing Complex
Transcription Preinitiation Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Protein-containing Complex
Extracellular Exosome
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase III General Transcription Initiation Factor Activity
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II General Transcription Initiation Factor Binding
TFIIB-class Transcription Factor Binding
RNA Polymerase II Repressing Transcription Factor Binding
Protein Binding
Transcription Factor Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Aryl Hydrocarbon Receptor Binding
Enzyme Binding
Repressing Transcription Factor Binding
General Transcription Initiation Factor Activity
RNA Polymerase II Complex Binding
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Protein Binding
Nuclear Receptor Binding
Nuclear Receptor Coactivator Activity
Nuclear Hormone Receptor Binding
Thyroid Hormone Receptor Binding
Protein Dimerization Activity
Protein N-terminus Binding
Disordered Domain Specific Binding
Biological Process
DNA-templated Transcription, Initiation
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription By RNA Polymerase III
Spermatogenesis
Viral Process
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
RNA Polymerase II Preinitiation Complex Assembly
Regulation Of Signal Transduction By P53 Class Mediator
Histone Acetylation
Cellular Response To Hormone Stimulus
Receptor Transactivation
Cell Dedifferentiation
Positive Regulation Of Keratinocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Estradiol Stimulus
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of Stem Cell Division
Pathways
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Estrogen-dependent gene expression
PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Activation of anterior HOX genes in hindbrain development during early embryogenesis
MAPK6/MAPK4 signaling
Estrogen-dependent gene expression
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Type 1 diabetes (
21980299
)
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Osteoarthritis (hip) (
23989986
)
Response to treatment for acute lymphoblastic leukemia (
19176441
)
Interacting Genes
122 interacting genes:
ABT1
AHR
AR
ATF4
BCL3
BRD2
BRF1
BRF2
BTAF1
CAND2
CITED2
COL26A1
CREG1
CREM
CTBP1
CTCFL
CUEDC2
CXXC1
DHX9
DR1
DRAP1
E2F1
EDF1
ELF3
ESR1
ETS1
FATE1
FOS
FOXF2
GOLGA2
GTF2A1
GTF2A1L
GTF2A2
GTF2B
GTF2E1
GTF2E2
GTF2F1
GTF2F2
GTF2H4
GTF3C2
GTF3C3
GTF3C4
GTF3C5
H3-4
HAP1
HMBOX1
HMGB1
HNF4A
HNRNPK
HSF1
HTT
HUWE1
IKZF1
JUN
JUND
JUP
KDM5A
KLF5
MBD2
MCM2
MDM2
MSX1
MYC
NACA
NCAPH
NCOA1
NCOA3
NCOA6
NFYB
NFYC
NR3C1
PAX3
PAX5
PAX6
PIAS1
PIAS3
POLR2A
POLR3F
POU2F1
POU2F2
POU3F2
PSMC2
PSME3
RB1
REL
RELA
REST
RNF4
RUVBL1
RUVBL2
RXRA
SERPINB5
SNAPC1
SNAPC2
SNAPC4
SP1
SPI1
SPIB
SSX2IP
SUB1
TAF1
TAF10
TAF11
TAF12
TAF13
TAF1A
TAF1B
TAF1C
TAF1L
TAF5
TAF7L
TCF12
TEAD1
TP53
TRAM2
TRIP4
UBE2I
UBTF
WDR62
YEATS2
YWHAE
ZNF76
82 interacting genes:
ABL1
ANKRD11
AR
ARNT2
ATAD2
BABAM2
BMP6
BMP7
BRCA1
CCND1
CDKN3
CHUK
CREBBP
CSNK1E
DCTN6
DDX17
DDX5
E2F1
EP300
ESR1
ESR2
ESRRA
ESRRB
ETV1
FOS
GSK3B
GTF2B
H3-4
H4-16
HNF1A
IKBKB
IKBKG
IQCK
JUN
KAT2B
MAPK1
MAPK14
MAPK8
MMS19
MN1
MRTFA
MRTFB
NCOR1
NCOR2
NKX2-1
NPAS2
NR0B2
NR1H2
NR1H3
NR1I2
NR1I3
NR2F1
NR3C1
NR4A1
NR5A2
PGR
PIN1
PPARA
PPARD
PPARG
PRKCZ
PRMT1
PSMB9
PSME3
RARA
RARB
RARG
RELA
RXRA
RXRB
SLC22A2
SMARCE1
SPOP
SUFU
SUMO1
TBP
THRB
TP53
TP53BP1
VDR
YWHAH
YWHAQ
Entrez ID
6908
8202
HPRD ID
02511
03570
Ensembl ID
ENSG00000112592
ENSG00000124151
Uniprot IDs
P20226
Q32MN7
Q59EE8
Q9Y6Q9
PDB IDs
1C9B
1CDW
1JFI
1NVP
1TGH
4ROC
4ROD
4ROE
5FUR
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
5N9G
6MZD
6MZL
6MZM
6O9L
1KBH
3L3X
3L3Z
6ES7
6SQC
Enriched GO Terms of Interacting Partners
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