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TBP and PAX3
Data Source:
BioGRID
(pull down)
TBP
PAX3
Description
TATA-box binding protein
paired box 3
Image
GO Annotations
Cellular Component
Chromatin
Euchromatin
Female Pronucleus
Male Pronucleus
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIA Complex
Cytoplasm
Protein-containing Complex
Transcription Preinitiation Complex
Chromatin
Nucleoplasm
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase III General Transcription Initiation Factor Activity
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II General Transcription Initiation Factor Binding
TFIIB-class Transcription Factor Binding
RNA Polymerase II Repressing Transcription Factor Binding
Protein Binding
Transcription Factor Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Aryl Hydrocarbon Receptor Binding
Enzyme Binding
Repressing Transcription Factor Binding
General Transcription Initiation Factor Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
HMG Box Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
DNA-templated Transcription, Initiation
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription By RNA Polymerase III
Spermatogenesis
Viral Process
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
RNA Polymerase II Preinitiation Complex Assembly
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Nervous System Development
Muscle Organ Development
Sensory Perception Of Sound
Animal Organ Morphogenesis
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Anatomical Structure Development
Pathways
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Estrogen-dependent gene expression
HATs acetylate histones
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
Alveolar rhabdomyosarcoma
Craniofacial-deafness-hand syndrome
Waardenburg syndrome (WS)
GWAS
Type 1 diabetes (
21980299
)
Adolescent idiopathic scoliosis (
26394188
)
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Blond vs. brown/black hair color (
30531825
)
Diisocyanate-induced asthma (
25918132
)
Facial morphology (
31763980
22341974
)
Facial morphology traits (63 three-dimensional facial segments) (
29459680
)
Information processing speed (
25869804
)
Male-pattern baldness (
28196072
)
middle facial morphology traits (quantitative measurement) (
27193062
)
Monobrow (
27182965
)
Monobrow thickness (
26926045
)
Nose size (
27182965
)
Vitamin D levels (
25208829
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
122 interacting genes:
ABT1
AHR
AR
ATF4
BCL3
BRD2
BRF1
BRF2
BTAF1
CAND2
CITED2
COL26A1
CREG1
CREM
CTBP1
CTCFL
CUEDC2
CXXC1
DHX9
DR1
DRAP1
E2F1
EDF1
ELF3
ESR1
ETS1
FATE1
FOS
FOXF2
GOLGA2
GTF2A1
GTF2A1L
GTF2A2
GTF2B
GTF2E1
GTF2E2
GTF2F1
GTF2F2
GTF2H4
GTF3C2
GTF3C3
GTF3C4
GTF3C5
H3-4
HAP1
HMBOX1
HMGB1
HNF4A
HNRNPK
HSF1
HTT
HUWE1
IKZF1
JUN
JUND
JUP
KDM5A
KLF5
MBD2
MCM2
MDM2
MSX1
MYC
NACA
NCAPH
NCOA1
NCOA3
NCOA6
NFYB
NFYC
NR3C1
PAX3
PAX5
PAX6
PIAS1
PIAS3
POLR2A
POLR3F
POU2F1
POU2F2
POU3F2
PSMC2
PSME3
RB1
REL
RELA
REST
RNF4
RUVBL1
RUVBL2
RXRA
SERPINB5
SNAPC1
SNAPC2
SNAPC4
SP1
SPI1
SPIB
SSX2IP
SUB1
TAF1
TAF10
TAF11
TAF12
TAF13
TAF1A
TAF1B
TAF1C
TAF1L
TAF5
TAF7L
TCF12
TEAD1
TP53
TRAM2
TRIP4
UBE2I
UBTF
WDR62
YEATS2
YWHAE
ZNF76
18 interacting genes:
CIB1
DAXX
FZR1
HDAC10
IPO13
KRTAP6-2
KRTAP8-1
MEOX1
MEOX2
MITF
MSX1
POU3F2
RAD23B
SOX10
SOX8
TAF1
TBP
WWTR1
Entrez ID
6908
5077
HPRD ID
02511
09421
Ensembl ID
ENSG00000112592
ENSG00000135903
Uniprot IDs
P20226
Q32MN7
P23760
PDB IDs
1C9B
1CDW
1JFI
1NVP
1TGH
4ROC
4ROD
4ROE
5FUR
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
5N9G
6MZD
6MZL
6MZM
6O9L
3CMY
Enriched GO Terms of Interacting Partners
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