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TBP and BRD2
Data Source:
BioGRID
(affinity chromatography technology, pull down, affinity chromatography technology)
TBP
BRD2
Description
TATA-box binding protein
bromodomain containing 2
Image
GO Annotations
Cellular Component
Chromatin
Euchromatin
Female Pronucleus
Male Pronucleus
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIA Complex
Cytoplasm
Protein-containing Complex
Transcription Preinitiation Complex
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase III General Transcription Initiation Factor Activity
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II General Transcription Initiation Factor Binding
TFIIB-class Transcription Factor Binding
RNA Polymerase II Repressing Transcription Factor Binding
Protein Binding
Transcription Factor Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Aryl Hydrocarbon Receptor Binding
Enzyme Binding
Repressing Transcription Factor Binding
General Transcription Initiation Factor Activity
Chromatin Binding
Protein Serine/threonine Kinase Activity
Protein Binding
Lysine-acetylated Histone Binding
Biological Process
DNA-templated Transcription, Initiation
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription By RNA Polymerase III
Spermatogenesis
Viral Process
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
RNA Polymerase II Preinitiation Complex Assembly
Regulation Of Signal Transduction By P53 Class Mediator
Neural Tube Closure
Nucleosome Assembly
Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Spermatogenesis
Viral Process
Pathways
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Estrogen-dependent gene expression
RUNX3 regulates p14-ARF
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Type 1 diabetes (
21980299
)
Asthma (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Crohn's disease (
28008999
)
Feeling nervous (
29500382
)
Hemoglobin levels (
32327693
)
Inflammatory bowel disease (
28008999
)
Ulcerative colitis (
28008999
)
Interacting Genes
122 interacting genes:
ABT1
AHR
AR
ATF4
BCL3
BRD2
BRF1
BRF2
BTAF1
CAND2
CITED2
COL26A1
CREG1
CREM
CTBP1
CTCFL
CUEDC2
CXXC1
DHX9
DR1
DRAP1
E2F1
EDF1
ELF3
ESR1
ETS1
FATE1
FOS
FOXF2
GOLGA2
GTF2A1
GTF2A1L
GTF2A2
GTF2B
GTF2E1
GTF2E2
GTF2F1
GTF2F2
GTF2H4
GTF3C2
GTF3C3
GTF3C4
GTF3C5
H3-4
HAP1
HMBOX1
HMGB1
HNF4A
HNRNPK
HSF1
HTT
HUWE1
IKZF1
JUN
JUND
JUP
KDM5A
KLF5
MBD2
MCM2
MDM2
MSX1
MYC
NACA
NCAPH
NCOA1
NCOA3
NCOA6
NFYB
NFYC
NR3C1
PAX3
PAX5
PAX6
PIAS1
PIAS3
POLR2A
POLR3F
POU2F1
POU2F2
POU3F2
PSMC2
PSME3
RB1
REL
RELA
REST
RNF4
RUVBL1
RUVBL2
RXRA
SERPINB5
SNAPC1
SNAPC2
SNAPC4
SP1
SPI1
SPIB
SSX2IP
SUB1
TAF1
TAF10
TAF11
TAF12
TAF13
TAF1A
TAF1B
TAF1C
TAF1L
TAF5
TAF7L
TCF12
TEAD1
TP53
TRAM2
TRIP4
UBE2I
UBTF
WDR62
YEATS2
YWHAE
ZNF76
8 interacting genes:
E2F1
E2F2
H2BC21
H2BU1
H4-16
SPOP
TBP
TOP1
Entrez ID
6908
6046
HPRD ID
02511
03326
Ensembl ID
ENSG00000112592
ENSG00000204256
Uniprot IDs
P20226
Q32MN7
A0A024RCR5
A0A1U9X7A8
P25440
X5CF57
PDB IDs
1C9B
1CDW
1JFI
1NVP
1TGH
4ROC
4ROD
4ROE
5FUR
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
5N9G
6MZD
6MZL
6MZM
6O9L
1X0J
2DVQ
2DVR
2DVS
2DVV
2E3K
2G4A
2YDW
2YEK
3AQA
3ONI
4A9E
4A9F
4A9H
4A9I
4A9J
4A9M
4A9N
4A9O
4AKN
4ALG
4ALH
4J1P
4MR5
4MR6
4QEU
4QEV
4QEW
4UYF
4UYG
4UYH
5BT5
5DFB
5DFC
5DFD
5DW1
5EK9
5HEL
5HEM
5HEN
5HFQ
5IBN
5IG6
5N2L
5O38
5O39
5O3A
5O3B
5O3C
5O3D
5O3E
5O3F
5O3G
5O3H
5O3I
5U5S
5U6V
5UEW
5XHE
5XHK
6CUI
6DB0
6DBC
6DDI
6DDJ
6E6J
6FFE
6FFF
6FFG
6I80
6I81
6JKE
6K04
6K05
6MO7
6MO8
6MO9
6MOA
6ONY
6SWO
6SWP
6TQ1
6TQ2
6U61
6U71
6U8H
6ULQ
6VIY
6YTM
6Z7F
6Z8P
6ZB0
6ZB1
6ZB2
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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