Description |
MDM4 regulator of p53 |
WD repeat domain 5 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Breast cancer ( 23535733 27117709)
- Breast cancer (estrogen-receptor negative) ( 27117709 29058716)
- Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative) ( 24325915)
- Breast Cancer in BRCA1 mutation carriers ( 23544013)
- Cognitive performance ( 19734545)
- Diastolic blood pressure ( 27618452 30578418)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Eosinophil counts ( 32888494)
- Eosinophil percentage of white cells ( 32888494)
- Fish- and plant-related diet ( 32066663)
- Glioma ( 28346443)
- Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) ( 32355309)
- Non-glioblastoma glioma ( 28346443)
- Oily fish consumption ( 32066663)
- Pork consumption ( 32066663)
- Prostate cancer ( 23535732)
- Regular attendance at a religious group ( 29970889)
- Systolic blood pressure ( 27618452)
- Type 2 diabetes ( 32499647)
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- Cerebrospinal fluid t-tau levels in normal cognition ( 29274321)
- Intraocular pressure ( 30591961)
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Interacting Genes |
63 interacting genes:
AKT1
APP
ARF1
ATM
BECN1
C1orf109
CAPN7
CASP3
CBLC
CD160
CD44
CDK1
CDK4
CDKN2A
CDKN2B
CHEK1
CHEK2
CSNK1A1
E2F1
EP300
EPHA2
FGFR4
GLIS2
HGF
LATS2
LRSAM1
MAGEA1
MAP2K5
MDM2
MKRN3
MNAT1
NAA10
NF2
PELI1
PRKAA1
RAD54B
RB1
RNF115
S100B
SFN
SMAD3
SMAD4
SMARCA2
TP53
TP63
TP73
TRIM46
TRIM55
UBC
UBE2D1
UBE2D2
UBE2D3
USP7
VPS26C
WDR5
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZKSCAN3
ZKSCAN4
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37 interacting genes:
ANAPC2
APP
ASH2L
ATN1
BBC3
BHLHE41
CHD8
FAM199X
H1-2
H3-4
H3C1
H4-16
HSF2
IKBKG
KANSL1
KANSL2
KMT2A
MARF1
MBIP
MDM4
MEOX2
MLLT1
NR2E3
PDE9A
POU5F1
PRMT5
PRNP
RBBP5
RUSC1-AS1
SRPK2
SRRM4
SSX2IP
TERF2IP
TP53
WWP2
ZBTB48
ZXDC
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Entrez ID |
4194 |
11091 |
HPRD ID |
04082 |
10614 |
Ensembl ID |
ENSG00000198625
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ENSG00000196363
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Uniprot IDs |
A0A087WTR9
A0A087WUE3
A0A087WZ58
O15151
Q59FS6
Q68DC0
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P61964
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PDB IDs |
2CR8
2MWY
2N06
2N0U
2N0W
2N14
2VJE
2VJF
2VYR
3DAB
3EQY
3FDO
3FE7
3FEA
3JZO
3JZP
3JZQ
3LBJ
3MQR
3U15
4RXZ
5MNJ
5UML
5VK1
6Q9Q
6Q9S
6Q9U
6Q9W
6Q9Y
7C3Q
7C3Y
7C44
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2CNX
2CO0
2G99
2G9A
2GNQ
2H13
2H14
2H68
2H6K
2H6N
2H6Q
2H9L
2H9M
2H9N
2H9P
2O9K
3EG6
3EMH
3MXX
3N0D
3N0E
3P4F
3PSL
3SMR
3UR4
3UVK
3UVL
3UVM
3UVN
3UVO
4A7J
4CY1
4CY2
4ERQ
4ERY
4ERZ
4ES0
4ESG
4EWR
4GM3
4GM8
4GM9
4GMB
4IA9
4O45
4QL1
4Y7R
5EAL
5EAM
5EAP
5EAR
5M23
5M25
5SXM
5VFC
6BYN
6D9X
6DAI
6DAK
6DAR
6DAS
6DY7
6DYA
6E1Y
6E1Z
6E22
6E23
6IAM
6KIU
6KIV
6KIW
6KIX
6KIZ
6OFZ
6OI0
6OI1
6OI2
6OI3
6PG3
6PG4
6PG5
6PG6
6PG7
6PG8
6PG9
6PGA
6PGB
6PGC
6PGD
6PGE
6PGF
6PWV
6PWW
6U5M
6U5Y
6U6W
6U80
6U8B
6U8L
6U8O
6UCS
6UFX
6UHY
6UHZ
6UIF
6UIK
6UJ4
6UJH
6UJJ
6UJL
6UOZ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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