Description |
MDM4 regulator of p53 |
ubiquitin conjugating enzyme E2 D1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Breast cancer ( 23535733 27117709)
- Breast cancer (estrogen-receptor negative) ( 27117709 29058716)
- Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative) ( 24325915)
- Breast Cancer in BRCA1 mutation carriers ( 23544013)
- Cognitive performance ( 19734545)
- Diastolic blood pressure ( 27618452 30578418)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Eosinophil counts ( 32888494)
- Eosinophil percentage of white cells ( 32888494)
- Fish- and plant-related diet ( 32066663)
- Glioma ( 28346443)
- Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) ( 32355309)
- Non-glioblastoma glioma ( 28346443)
- Oily fish consumption ( 32066663)
- Pork consumption ( 32066663)
- Prostate cancer ( 23535732)
- Regular attendance at a religious group ( 29970889)
- Systolic blood pressure ( 27618452)
- Type 2 diabetes ( 32499647)
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Interacting Genes |
63 interacting genes:
AKT1
APP
ARF1
ATM
BECN1
C1orf109
CAPN7
CASP3
CBLC
CD160
CD44
CDK1
CDK4
CDKN2A
CDKN2B
CHEK1
CHEK2
CSNK1A1
E2F1
EP300
EPHA2
FGFR4
GLIS2
HGF
LATS2
LRSAM1
MAGEA1
MAP2K5
MDM2
MKRN3
MNAT1
NAA10
NF2
PELI1
PRKAA1
RAD54B
RB1
RNF115
S100B
SFN
SMAD3
SMAD4
SMARCA2
TP53
TP63
TP73
TRIM46
TRIM55
UBC
UBE2D1
UBE2D2
UBE2D3
USP7
VPS26C
WDR5
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZKSCAN3
ZKSCAN4
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239 interacting genes:
AMFR
ANAPC11
ANXA1
ANXA7
AREL1
ARIH1
ARIH2
ARRDC3
ASB2
ASB4
ASB9
BABAM2
BARD1
BFAR
BIK
BIRC2
BIRC3
BIRC6
BIRC7
BIRC8
BRCA1
BRCC3
BRMS1
C7orf25
CADPS2
CBL
CBLC
CDK7
CDKN1A
CHFR
CNOT4
COP1
CRBN
CREBBP
CRYAB
CTNNB1
CUL2
CUL3
DDX58
DTL
DTX1
DTX2
DTX3
DTX3L
DYRK2
DZIP3
EP300
EPS15
F12
FAF2
FBXL17
FBXL2
FBXO2
FBXO7
FOS
FZR1
GADD45A
GSK3B
H3C1
H4C1
HDAC6
HECW1
HERC2
HERC3
HERC5
HIF1A
HSD17B10
HUWE1
ITCH
KAT2B
KCTD17
KDM2B
KLHL13
KLHL2
KLHL9
LNPK
LRR1
LRSAM1
LTN1
MAP3K1
MARCHF1
MARCHF2
MARCHF4
MARCHF5
MARCHF7
MARCHF8
MDM2
MDM4
MEOX2
MGRN1
MIB1
MID1
MID2
MKNK1
MKRN1
MKRN2
MKRN3
MUL1
NBN
NEDD4
NEDD4L
NEURL1
NFKBIA
NHLRC1
NONO
NQO1
NR1H2
OBI1
OTUB1
OTULIN
PELI1
PER2
PJA2
POLL
POLM
PRKN
RABGEF1
RAG1
RBCK1
RBX1
RCHY1
RELA
RFFL
RFWD3
RING1
RLIM
RMND5A
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF122
RNF123
RNF125
RNF126
RNF128
RNF13
RNF130
RNF14
RNF144A
RNF150
RNF165
RNF166
RNF167
RNF168
RNF181
RNF182
RNF185
RNF2
RNF216
RNF25
RNF26
RNF31
RNF38
RNF4
RNF43
RNF5
RNF6
RNF7
RNF8
RSAD2
SH3RF1
SHPRH
SIAH1
SIAH2
SIRT6
SIVA1
SKP1
SMURF1
SMURF2
SPOP
STAM2
STUB1
SUFU
TAF1D
TBL1X
TMEM129
TNFAIP3
TNNT1
TOM1
TOPORS
TP53
TRAF2
TRAF4
TRAF6
TRAF7
TRAIP
TRIM10
TRIM17
TRIM2
TRIM21
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM3
TRIM31
TRIM32
TRIM35
TRIM37
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM55
TRIM62
TRIM63
TRIM69
TRIM7
TRIM8
TRIP12
TSC22D1
UBA1
UBA6
UBASH3B
UBC
UBE3A
UBE3C
UBE4A
UBOX5
UBTD1
UFM1
UHRF1
UHRF2
UVSSA
VHL
WWP1
WWP2
XIAP
ZNF598
ZNRF1
ZNRF2
ZNRF4
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Entrez ID |
4194 |
7321 |
HPRD ID |
04082 |
04267 |
Ensembl ID |
ENSG00000198625
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ENSG00000072401
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Uniprot IDs |
A0A087WTR9
A0A087WUE3
A0A087WZ58
O15151
Q59FS6
Q68DC0
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A0A024QZJ2
A0A087WW00
P51668
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PDB IDs |
2CR8
2MWY
2N06
2N0U
2N0W
2N14
2VJE
2VJF
2VYR
3DAB
3EQY
3FDO
3FE7
3FEA
3JZO
3JZP
3JZQ
3LBJ
3MQR
3U15
4RXZ
5MNJ
5UML
5VK1
6Q9Q
6Q9S
6Q9U
6Q9W
6Q9Y
7C3Q
7C3Y
7C44
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2C4P
2YHO
3OJ4
3PTF
4AP4
4QPL
5FER
5TUT
6D4P
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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