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WT1 and KRTAP10-7
Data Source:
BioGRID
(two hybrid, two hybrid)
WT1
KRTAP10-7
Description
WT1 transcription factor
keratin associated protein 10-7
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Nuclear Speck
Cytosol
Keratin Filament
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
RNA Binding
Protein Binding
Zinc Ion Binding
Double-stranded Methylated DNA Binding
Sequence-specific DNA Binding
Hemi-methylated DNA-binding
C2H2 Zinc Finger Domain Binding
Protein Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Vasculogenesis
Ureteric Bud Development
Branching Involved In Ureteric Bud Morphogenesis
Kidney Development
Regulation Of Animal Organ Formation
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Germ Cell Development
Thorax And Anterior Abdomen Determination
Heart Development
Sex Determination
Negative Regulation Of Cell Population Proliferation
RNA Splicing
Gonad Development
Male Gonad Development
Tissue Development
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Growth
Adrenal Gland Development
Male Genitalia Development
Epithelial Cell Differentiation
Glomerulus Development
Glomerular Basement Membrane Development
Adrenal Cortex Formation
Camera-type Eye Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Mesenchymal To Epithelial Transition
Positive Regulation Of Heart Growth
Diaphragm Development
Cardiac Muscle Cell Fate Commitment
Visceral Serous Pericardium Development
Cellular Response To CAMP
Cellular Response To Gonadotropin Stimulus
Metanephric Mesenchyme Development
Glomerular Visceral Epithelial Cell Differentiation
Posterior Mesonephric Tubule Development
Metanephric Epithelium Development
Metanephric S-shaped Body Morphogenesis
Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of DNA Methylation
Positive Regulation Of Male Gonad Development
Negative Regulation Of Female Gonad Development
Positive Regulation Of Metanephric Ureteric Bud Development
Keratinization
Pathways
Transcriptional regulation of testis differentiation
Keratinization
Drugs
Diseases
Nephrotic syndrome and focal segmental glomerulosclerosis
46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Apolipoprotein A1 levels (
32203549
)
Birth weight (
31043758
)
Coronary artery disease (
33020668
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Endometrial cancer (
30093612
)
Endometrial cancer (endometrioid histology) (
30093612
)
Inguinal hernia (
26686553
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Medication use (diuretics) (
31015401
)
Offspring birth weight (
31043758
)
Pelvic organ prolapse (
32184442
)
PR interval (
32439900
)
Pulse pressure (
30224653
)
Resting-state electroencephalogram vigilance (
29703947
)
Rubella-specific interleukin-6 secretion (
29253144
)
Tuberculosis (
24057671
22306650
)
Uterine fibroids (
31249589
30194396
31649266
)
Interacting Genes
64 interacting genes:
AREG
BHLHE40
CASZ1
CCDC136
CCDC33
CCL5
CEP70
CIAO1
CREBBP
CYSRT1
DIRAS3
DVL2
DVL3
EGR1
ETV7
FAM9B
FHL2
FMR1NB
GLIS2
GOLGA2
HMBOX1
IDI1
IPO8
KLK7
KPNA4
KPNA5
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-4
KRTAP10-5
KRTAP10-6
KRTAP10-7
KRTAP10-8
KRTAP10-9
LDOC1
MAGEA8
MDM2
MYC
NAT2
NPM3
OSBPL3
PAWR
PAX2
PICK1
PRKACA
RNASEH2B
SERF2
SOX4
STK11
TAOK1
THAP1
THRSP
TP53
TP63
TP73
TRIM55
TRIM63
U2AF2
UBE2I
WTAP
WTIP
ZNF205
ZRANB1
282 interacting genes:
AEN
ALDH3B1
ANKRD36BP1
AP1M1
APP
AQP1
AVPI1
B4GALT7
BAHD1
BCL6B
BMP7
BRME1
BUD31
BYSL
C8orf33
CARHSP1
CATIP
CBX2
CCDC185
CCDC26
CCNG1
CDCA7L
CHIC2
CHRD
CHRNG
CLK1
CLK4
CNNM3
COL8A1
CRCT1
CREB5
CRY2
CSNK1G1
CSNK1G2
CTNNBIP1
CTRC
CXCL16
CYSRT1
DAAM2
DERL2
DHX57
DMRT3
DOCK2
E2F6
E4F1
EHHADH
FADS6
FAM124B
FAM161A
FAM27E3
FAM74A4
FAM76B
FARS2
GABARAPL1
GABARAPL2
GEM
GLIDR
GLP1R
GNE
GOLGA8EP
GRN
GSTP1
GUCD1
HBZ
HCK
HHEX
HOXA1
HOXC8
HPCAL1
HSBP1
HSD3B7
IGSF8
ING5
INPP5D
IQUB
ITGB4
ITGB5
KLHL38
KRT20
KRT83
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-3
KRTAP26-1
KRTAP4-2
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1D
LCE1F
LCE2A
LCE2B
LCE2C
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LIMS2
LINC00242
LMNA
LMO2
LRCH4
MAPKBP1
MCM5
MCRS1
MOBP
MRGBP
MXD3
MXI1
MYPOP
NAA10
NAXD
NECTIN2
NECTIN3
NKD1
NOL12
NOTCH2NLA
NPBWR2
NPDC1
NTAQ1
NUBP2
NUDCD3
NUFIP2
OTX1
P2RY6
PCED1A
PCSK5
PDE9A
PDIA5
PDLIM5
PFKL
PGAP6
PHLDA1
PIN1
POLL
POM121L8P
PPARD
PRKAB2
PRM2
PRR13
PRR35
PTGDS
PTGER3
PTPMT1
PVR
R3HDM2
RNF175
RPF1
RPL11
RPL36AL
RPS28
RPUSD3
RSPO2
RTN4RL1
RWDD2B
SCNM1
SDCBP
SHFL
SLC23A1
SLC25A48
SLC6A20
SMCO4
SMCP
SPACA9
SPATA24
SPATA3
SPATA8
SPG7
SPRY1
SSX2IP
STAT3
STK16
SUV39H1
TAPBPL
TCEA2
TCEANC
TEDC2
TFAP2D
THAP1
THAP6
TLE5
TMA16
TNP2
TNS2
TOR1A
TREX1
TRIM42
TTPA
TULP3
TXNDC5
TYRO3
UCP2
UXT
VASN
VGLL3
VTI1B
WNT11
WT1
ZBTB24
ZBTB38
ZBTB48
ZBTB9
ZFP41
ZFYVE26
ZIM2
ZNF101
ZNF124
ZNF133
ZNF138
ZNF155
ZNF165
ZNF169
ZNF175
ZNF180
ZNF2
ZNF20
ZNF223
ZNF250
ZNF256
ZNF26
ZNF260
ZNF264
ZNF266
ZNF32
ZNF320
ZNF329
ZNF337
ZNF408
ZNF41
ZNF414
ZNF417
ZNF418
ZNF419
ZNF420
ZNF425
ZNF433
ZNF439
ZNF440
ZNF444
ZNF490
ZNF491
ZNF524
ZNF543
ZNF555
ZNF564
ZNF572
ZNF575
ZNF578
ZNF580
ZNF581
ZNF587
ZNF625
ZNF667
ZNF670
ZNF696
ZNF697
ZNF707
ZNF764
ZNF774
ZNF778
ZNF786
ZNF792
ZNF837
ZNF844
ZNF846
ZNHIT1
ZSCAN10
ZSCAN21
ZSCAN26
Entrez ID
7490
386675
HPRD ID
06163
11193
Ensembl ID
ENSG00000184937
ENSG00000272804
Uniprot IDs
P19544
Q6PI38
P60409
PDB IDs
1LU6
1XF7
2G7T
2G7V
2G7W
2G7X
2JP9
2JPA
2PRT
3HPJ
3MYJ
4R2E
4R2P
4R2Q
4R2R
4R2S
4WUU
5KL2
5KL3
5KL4
5KL5
5KL6
5KL7
6B0O
6B0P
6B0Q
6B0R
6BLW
6RSY
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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