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WT1 and KRTAP10-9
Data Source:
BioGRID
(two hybrid)
WT1
KRTAP10-9
Description
WT1 transcription factor
keratin associated protein 10-9
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Nuclear Speck
Cytosol
Keratin Filament
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
RNA Binding
Protein Binding
Zinc Ion Binding
Double-stranded Methylated DNA Binding
Sequence-specific DNA Binding
Hemi-methylated DNA-binding
C2H2 Zinc Finger Domain Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Vasculogenesis
Ureteric Bud Development
Branching Involved In Ureteric Bud Morphogenesis
Kidney Development
Regulation Of Animal Organ Formation
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Germ Cell Development
Thorax And Anterior Abdomen Determination
Heart Development
Sex Determination
Negative Regulation Of Cell Population Proliferation
RNA Splicing
Gonad Development
Male Gonad Development
Tissue Development
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Growth
Adrenal Gland Development
Male Genitalia Development
Epithelial Cell Differentiation
Glomerulus Development
Glomerular Basement Membrane Development
Adrenal Cortex Formation
Camera-type Eye Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Mesenchymal To Epithelial Transition
Positive Regulation Of Heart Growth
Diaphragm Development
Cardiac Muscle Cell Fate Commitment
Visceral Serous Pericardium Development
Cellular Response To CAMP
Cellular Response To Gonadotropin Stimulus
Metanephric Mesenchyme Development
Glomerular Visceral Epithelial Cell Differentiation
Posterior Mesonephric Tubule Development
Metanephric Epithelium Development
Metanephric S-shaped Body Morphogenesis
Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of DNA Methylation
Positive Regulation Of Male Gonad Development
Negative Regulation Of Female Gonad Development
Positive Regulation Of Metanephric Ureteric Bud Development
Keratinization
Pathways
Transcriptional regulation of testis differentiation
Keratinization
Drugs
Diseases
Nephrotic syndrome and focal segmental glomerulosclerosis
46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Apolipoprotein A1 levels (
32203549
)
Birth weight (
31043758
)
Coronary artery disease (
33020668
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Endometrial cancer (
30093612
)
Endometrial cancer (endometrioid histology) (
30093612
)
Inguinal hernia (
26686553
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Medication use (diuretics) (
31015401
)
Offspring birth weight (
31043758
)
Pelvic organ prolapse (
32184442
)
PR interval (
32439900
)
Pulse pressure (
30224653
)
Resting-state electroencephalogram vigilance (
29703947
)
Rubella-specific interleukin-6 secretion (
29253144
)
Tuberculosis (
24057671
22306650
)
Uterine fibroids (
31249589
30194396
31649266
)
Interacting Genes
64 interacting genes:
AREG
BHLHE40
CASZ1
CCDC136
CCDC33
CCL5
CEP70
CIAO1
CREBBP
CYSRT1
DIRAS3
DVL2
DVL3
EGR1
ETV7
FAM9B
FHL2
FMR1NB
GLIS2
GOLGA2
HMBOX1
IDI1
IPO8
KLK7
KPNA4
KPNA5
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-4
KRTAP10-5
KRTAP10-6
KRTAP10-7
KRTAP10-8
KRTAP10-9
LDOC1
MAGEA8
MDM2
MYC
NAT2
NPM3
OSBPL3
PAWR
PAX2
PICK1
PRKACA
RNASEH2B
SERF2
SOX4
STK11
TAOK1
THAP1
THRSP
TP53
TP63
TP73
TRIM55
TRIM63
U2AF2
UBE2I
WTAP
WTIP
ZNF205
ZRANB1
226 interacting genes:
ADAMTSL4
ALDH3B1
ALPI
ANKS1A
ARFGAP1
ATXN7L1
AVPI1
BCL6B
BMP7
BRME1
C10orf62
C11orf87
C22orf39
C5orf60
CATIP
CATSPER1
CBX2
CCDC26
CD300LG
CDKL3
CHIC2
CHRD
CHRNG
CKS1B
CLK4
CNNM3
CRCT1
CREB5
CST9L
CXCL16
CYSRT1
DHRS1
DHX57
DMRT3
DOCK2
EIF4E2
EZH2
FAM124B
FAM161A
FAM74A4
FAM76B
FARS2
FBXW5
GABARAPL1
GABARAPL2
GATA2
GLIDR
GLP1R
GLRX3
GNE
GPATCH2L
GSTP1
GUCD1
HBG1
HBZ
HCK
HES6
HOXA1
HOXB9
HOXC8
HPCAL1
HSBP1
HSD3B7
IGSF8
INPP5D
IQUB
ITGB4
ITGB5
KAT5
KIAA0040
KIF9
KLHL38
KRT20
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-1
KRTAP12-3
KRTAP26-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-11
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-4
LCE1A
LCE1B
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LUZP4
MAB21L3
MAPKBP1
MAZ
MED30
MEOX2
MOBP
MT1DP
MXI1
MYPOP
NAXD
NBPF19
NECTIN3
NKD1
NOTCH2NLA
NPBWR2
NPDC1
NPPB
NR1D2
NUFIP2
OTX1
PCSK5
PDE9A
PDGFRB
PGAP2
PGLS
PIGS
PIN1
PLSCR1
POU4F2
PRKAA2
PRKAB2
PRPF31
PTGER3
PTPMT1
PVR
RAB7A
RASD1
RHNO1
RSPO2
SCARB1
SCNM1
SEMA3B
SHFL
SLC23A1
SLC6A20
SMARCE1
SMCP
SPACA9
SPATA3
SPATA8
SPG7
SPRY1
SPRY2
STK16
TBC1D16
TBC1D23
TBC1D26
TEDC2
TGOLN2
THAP10
TLE5
TNFRSF6B
TNP2
TRIM41
TRIM42
TXNDC5
TYMSOS
TYRO3
UTP23
VGLL3
WNT11
WT1
WT1-AS
XCL2
YIPF3
YY1
ZBTB24
ZBTB38
ZBTB9
ZFYVE26
ZNF124
ZNF155
ZNF165
ZNF20
ZNF251
ZNF264
ZNF275
ZNF286A
ZNF317
ZNF319
ZNF417
ZNF433
ZNF439
ZNF440
ZNF473
ZNF497
ZNF524
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF599
ZNF625
ZNF688
ZNF696
ZNF697
ZNF699
ZNF764
ZNF774
ZNF777
ZNF792
ZNF80
ZNF837
ZNF844
ZNF860
ZSCAN21
ZSCAN26
Entrez ID
7490
386676
HPRD ID
06163
11195
Ensembl ID
ENSG00000184937
ENSG00000221837
Uniprot IDs
P19544
Q6PI38
P60411
PDB IDs
1LU6
1XF7
2G7T
2G7V
2G7W
2G7X
2JP9
2JPA
2PRT
3HPJ
3MYJ
4R2E
4R2P
4R2Q
4R2R
4R2S
4WUU
5KL2
5KL3
5KL4
5KL5
5KL6
5KL7
6B0O
6B0P
6B0Q
6B0R
6BLW
6RSY
Enriched GO Terms of Interacting Partners
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