TXNRD1 and POU2F2

Data Source:
BioGRID (pull down)

		TXNRD1	POU2F2
Description		thioredoxin reductase 1	POU class 2 homeobox 2
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GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Thioredoxin-disulfide Reductase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Flavin Adenine Dinucleotide Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mesoderm Formation Selenium Compound Metabolic Process Signal Transduction Cell Population Proliferation Nucleobase-containing Small Molecule Interconversion Regulation Of Lipid Metabolic Process Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification	Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Positive Regulation Of Interleukin-6 Production SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus
Pathways		PPARA activates gene expression Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Detoxification of Reactive Oxygen Species Interconversion of nucleotide di- and triphosphates Metabolism of ingested MeSeO2H into MeSeH Uptake and function of diphtheria toxin TP53 Regulates Metabolic Genes	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs		Arsenic trioxide NADPH Flavin adenine dinucleotide Spermidine Fotemustine Motexafin gadolinium PX-12
Diseases
GWAS		Blood protein levels ( 30072576) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Logical memory (delayed recall) in normal cognition ( 29274321) Toenail selenium levels ( 25343990)	Alcohol consumption (drinks per week) ( 30643258) Chronotype ( 30696823) Eosinophil counts ( 32888494) Meat-related diet ( 32066663) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016)
Interacting Genes		11 interacting genes: DMRTC2 ESR1 ESR2 GLRX2 LINC01554 POU2F1 POU2F2 PPP1R16A THRA TXNDC17 TXNIP	15 interacting genes: AR ESR1 GAPDH HMGA1 HMGB2 MNAT1 MSX2 NR2F1 NR3C1 PGR POU2AF1 RXRA TBP TXNRD1 XRCC6
Entrez ID		7296	5452
HPRD ID		03068	01251
Ensembl ID		ENSG00000198431	ENSG00000028277
Uniprot IDs		B7Z2S5 Q16881	B5ME60 H0YLL6 P09086
PDB IDs		1W1C 2CFY 2J3N 2ZZ0 2ZZB 2ZZC 3QFA 3QFB	1HDP
Enriched GO Terms of Interacting Partners?
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