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POU2F2 and HMGB2
Data Source:
HPRD
(in vitro, in vivo)
POU2F2
HMGB2
Description
POU class 2 homeobox 2
high mobility group box 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Intracellular Membrane-bounded Organelle
Chromatin
Condensed Chromosome
Extracellular Space
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Four-way Junction DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
Damaged DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
Transcription Factor Binding
DNA Binding, Bending
Protein Domain Specific Binding
Chemoattractant Activity
Non-sequence-specific DNA Binding, Bending
RAGE Receptor Binding
Supercoiled DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Humoral Immune Response
Positive Regulation Of Interleukin-6 Production
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Virus
Positive Regulation Of Endothelial Cell Proliferation
Inflammatory Response To Antigenic Stimulus
DNA Topological Change
Double-strand Break Repair Via Nonhomologous End Joining
Apoptotic DNA Fragmentation
Chromatin Organization
Nucleosome Assembly
Regulation Of Transcription By RNA Polymerase II
Spermatid Nucleus Differentiation
Male Gonad Development
Positive Regulation Of Nuclease Activity
DNA Geometric Change
Response To Lipopolysaccharide
Positive Regulation Of Interferon-beta Production
V(D)J Recombination
Positive Regulation Of DNA Binding
Innate Immune Response
Positive Regulation Of Innate Immune Response
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Response To Steroid Hormone
Regulation Of Neurogenesis
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Positive Chemotaxis
Cell Chemotaxis
Cellular Response To Lipopolysaccharide
Regulation Of Stem Cell Proliferation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS
Alcohol consumption (drinks per week) (
30643258
)
Chronotype (
30696823
)
Eosinophil counts (
32888494
)
Meat-related diet (
32066663
)
Prostate cancer (
29892016
)
Prostate cancer (advanced) (
29892016
)
Interacting Genes
15 interacting genes:
AR
ESR1
GAPDH
HMGA1
HMGB2
MNAT1
MSX2
NR2F1
NR3C1
PGR
POU2AF1
RXRA
TBP
TXNRD1
XRCC6
38 interacting genes:
APEX1
APP
AR
ARCN1
C1QBP
CACTIN
CHAF1A
CREBBP
CSNK1A1
EIF1
FBXO7
GZMA
GZMK
H3-3A
HACD3
HDLBP
HMGA1
LZTS1
MIEN1
NAP1L1
NCBP3
NEXN
NR3C1
PGR
PKNOX1
POU2F1
POU2F2
POU3F1
POU5F1
PRKDC
RAG1
SAMM50
SET
TP53
TSNAX
ZNF428
ZNF622
ZNF668
Entrez ID
5452
3148
HPRD ID
01251
01229
Ensembl ID
ENSG00000028277
ENSG00000164104
Uniprot IDs
B5ME60
H0YLL6
P09086
P26583
PDB IDs
1HDP
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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