TAC1 and MEP1A

Data Source:
HPRD (in vitro)

		TAC1	MEP1A
Description		tachykinin precursor 1	meprin A subunit alpha
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Axon Neuronal Cell Body Synapse	Extracellular Space Integral Component Of Plasma Membrane Meprin A Complex Extracellular Exosome
	Molecular Function	Substance P Receptor Binding	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Insemination Long-term Memory Regulation Of Blood Pressure Associative Learning Detection Of Abiotic Stimulus Response To Hormone Negative Regulation Of Heart Rate Positive Regulation Of Epithelial Cell Migration Sensory Perception Of Pain Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Positive Regulation Of Renal Sodium Excretion Response To Morphine Positive Regulation Of Action Potential Positive Regulation Of Ossification Positive Regulation Of Saliva Secretion Response To Pain Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Stress Fiber Assembly Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Corticosterone Secretion	Proteolysis
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to radiation therapy ( 23719583) Blood protein levels ( 30072576) Feeling nervous ( 29500382) General risk tolerance (MTAG) ( 30643258) Regular attendance at a religious group ( 29970889) Response to platinum-based agents ( 22020760) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		10 interacting genes: ARHGEF40 BAG6 CENPB FN1 MEP1A PREP TACR1 TACR2 TACR3 XRCC6	18 interacting genes: AGT CCK FN1 GCG GNRH1 GRP KNG1 LAMA1 LAMA5 MEP1B NPY NTS PLG POMC PTH SCT TAC1 VIP
Entrez ID		6863	4224
HPRD ID		08876	02666
Ensembl ID		ENSG00000006128	ENSG00000112818
Uniprot IDs		P20366 Q9Y494	B7ZL91 Q16819
PDB IDs		2B19 2KS9 2KSA 2KSB 4HOM
Enriched GO Terms of Interacting Partners?
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