MEP1A and GNRH1

Data Source:
HPRD (in vitro)

		MEP1A	GNRH1
Description		meprin A subunit alpha	gonadotropin releasing hormone 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane Meprin A Complex Extracellular Exosome	Extracellular Region Extracellular Space Mitochondrion Golgi-associated Vesicle Dendrite Perikaryon Axon Terminus Cytoplasmic Side Of Rough Endoplasmic Reticulum Membrane Neurosecretory Vesicle
	Molecular Function	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding	Hormone Activity Gonadotropin Hormone-releasing Hormone Activity Gonadotropin-releasing Hormone Receptor Binding
	Biological Process	Proteolysis	Reproduction Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organism Development Female Pregnancy Aging Negative Regulation Of Cell Population Proliferation Regulation Of Gene Expression Male Sex Determination Response To Corticosteroid Response To Lipopolysaccharide Negative Regulation Of Immature T Cell Proliferation Response To Testosterone Response To Prostaglandin E Response To Potassium Ion Negative Regulation Of Apoptotic Process Estrous Cycle Response To Ethanol Response To Prolactin Regulation Of Ovarian Follicle Development Negative Regulation Of Neuron Migration
Pathways			Hormone ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Length of menstrual cycle ( 30202859) Menopause (age at onset) ( 29773799) Metabolite levels ( 23823483) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		18 interacting genes: AGT CCK FN1 GCG GNRH1 GRP KNG1 LAMA1 LAMA5 MEP1B NPY NTS PLG POMC PTH SCT TAC1 VIP	2 interacting genes: GNRHR MEP1A
Entrez ID		4224	2796
HPRD ID		02666	08860
Ensembl ID		ENSG00000112818	ENSG00000147437
Uniprot IDs		B7ZL91 Q16819	P01148
PDB IDs			4D5M
Enriched GO Terms of Interacting Partners?
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