MEP1A and CCK

Data Source:
HPRD (in vitro)

		MEP1A	CCK
Description		meprin A subunit alpha	cholecystokinin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane Meprin A Complex Extracellular Exosome	Extracellular Region Extracellular Space Axon Dendrite Axon Initial Segment Terminal Bouton Axon Hillock Perikaryon
	Molecular Function	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding	Hormone Activity Neuropeptide Hormone Activity Protein Binding Peptide Hormone Receptor Binding
	Biological Process	Proteolysis	Neuron Migration Release Of Cytochrome C From Mitochondria Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Digestion Memory Positive Regulation Of Cell Population Proliferation Visual Learning Positive Regulation Of Glutamate Secretion Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Appetite Eating Behavior Positive Regulation Of Apoptotic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Negative Regulation Of Behavioral Fear Response Positive Regulation Of Behavioral Fear Response
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Camostat
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 24348519 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (SNP x SNP interaction) ( 22344221) Body size at age 10 ( 32376654) Night sleep phenotypes ( 27126917)
Interacting Genes		18 interacting genes: AGT CCK FN1 GCG GNRH1 GRP KNG1 LAMA1 LAMA5 MEP1B NPY NTS PLG POMC PTH SCT TAC1 VIP	7 interacting genes: CCKAR CCKBR CPE ENPEP MEP1A MEP1B UBQLN2
Entrez ID		4224	885
HPRD ID		02666	00321
Ensembl ID		ENSG00000112818	ENSG00000187094
Uniprot IDs		B7ZL91 Q16819	P06307 Q6FG82
PDB IDs
Enriched GO Terms of Interacting Partners?
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