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ZNF417 and CARD9
Data Source:
BioGRID
(two hybrid)
ZNF417
CARD9
Description
zinc finger protein 417
caspase recruitment domain family member 9
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Protein-containing Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Protein Binding
Protein Homodimerization Activity
CARD Domain Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Stimulatory C-type Lectin Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
Response To Fungus
Response To Peptidoglycan
Response To Muramyl Dipeptide
Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Response To Drug
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Exogenous DsRNA
Innate Immune Response
Positive Regulation Of JNK Cascade
Defense Response To Gram-positive Bacterium
Defense Response To Virus
Pathways
Generic Transcription Pathway
NOD1/2 Signaling Pathway
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Depression in smokers (
30219690
)
Acute insulin response (insulin secretion adjusted) (
28490609
)
Ankylosing spondylitis (
23749187
21743469
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
22936669
21102463
)
IgA nephropathy (
25305756
)
Inflammatory bowel disease (
28067908
23128233
)
Joint damage in rheumatoid arthritis (
26498133
)
Large artery stroke (
28265093
)
Monocyte chemoattractant protein-1 levels (
23017229
)
Obesity-related traits (
23251661
)
Pediatric autoimmune diseases (
26301688
)
Ulcerative colitis (
19915572
28067908
20228799
21297633
)
Interacting Genes
169 interacting genes:
ADAMTSL4
AXIN2
BEGAIN
BEND5
BEX3
BHLHB9
BICD2
C4orf17
CARD9
CBY2
CCDC125
CCDC136
CCDC57
CCDC85B
CCNDBP1
CDR2
CDR2L
CEP44
CEP70
CEP72
CEP85L
CHRDL2
COG6
CSRNP1
CYSRT1
DEF8
DVL3
EFS
EZHIP
FAM221A
FHL2
FHL3
FHL5
FRS3
FSD2
FXR1
GOLGA2
GOLGA6L9
HMBOX1
HOMEZ
HOOK2
HOXA1
HSF2BP
IGFBP6
IHO1
IKZF1
INKA1
JADE2
JRK
KAT5
KATNBL1
KCTD7
KIF9
KIFC3
KLC3
KRT15
KRT31
KRT35
KRT38
KRT39
KRT40
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-9
KXD1
LHX3
LIMS1
LMO1
LURAP1
LZTS1
LZTS2
MAGEA8
MAST2
MCC
MCCD1
MDFI
MEIS3
MEOX2
MID2
MIIP
MRFAP1L1
MTUS2
MYF5
MYLIP
NAB2
NBPF19
NDEL1
NDUFB7
NINL
NKAPL
NKX3-1
NOTCH2NLA
OIP5
PHC2
PICK1
PIH1D2
PLSCR1
PNMA2
PRICKLE4
PRPF31
RCN3
REL
RHOQ
RNF187
RORB
RPGRIP1
RUNDC3A
SH2B2
SMARCD1
SMYD5
SPRED1
SPRED2
SPRY1
SPRY2
SSX2IP
STX11
SUV39H1
TADA2A
TCF4
TEKT4
TFIP11
TLE5
TMCC2
TNS2
TRAF1
TRAF2
TRIB3
TRIM23
TRIM27
TRIM36
TRIM37
TRIM41
TRIM54
TSC1
TSGA10
TXNDC11
U2AF1
U2AF1L5
USHBP1
VPS16
VPS52
VWC2
ZBTB1
ZBTB10
ZBTB43
ZBTB8A
ZBTB9
ZNF165
ZNF19
ZNF20
ZNF547
ZNF572
ZNF587
ZNF69
ZNF71
ZNF768
ZNF774
ZNF837
ZNF85
ZRANB1
138 interacting genes:
ABLIM1
AMOTL2
AXIN1
BCL10
BLZF1
C1orf94
C2CD6
CABP2
CARD10
CBX8
CCDC13
CCDC136
CCDC85B
CCDC88B
CCHCR1
CDC37
CDCA7L
CDK2AP1
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DISC1
DUSP13
DVL2
EFHC2
EIF4A3
EIF4E2
FAM124B
FAM161A
FAM161B
FAM50B
FAM90A1
FOXD4L1
GAS8
GEM
HMBOX1
HOXB5
HSF2BP
IHO1
IKZF3
INO80B
IQCE
KANK2
KCTD9
KIAA0408
KIAA1328
KIF9
KIFC3
KRT15
KRT16
KRT19
KRT31
KRT40
KRT75
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP5-7
L3MBTL2
LENG1
LMO1
LMO3
LNX1
LZTS1
LZTS2
MCRS1
MEOX2
MFAP1
MID2
MYO15B
NECAB2
NTAQ1
PAK5
PBX2
PHC2
PIBF1
PICK1
PKP2
PNMA5
PPP1R18
PRPF18
PSMA4
RBAK
RTP5
SAXO1
SCNM1
SHISA6
SLAIN1
SSX2IP
STMN3
STX11
SUMO1
TASOR2
TCEANC
TCL1A
TEX33
TFIP11
TLE5
TNFAIP1
TNS4
TRIM14
TRIM23
TRIM29
TRIM42
TRIM54
TRIM62
TSGA10IP
TSNAX
UBE2I
UNKL
USH1G
USP15
USP2
VCPKMT
VPS28
YES1
ZBTB16
ZC2HC1C
ZCCHC7
ZGPAT
ZMYM5
ZNF121
ZNF19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF572
ZNF587
ZNF620
ZNF655
ZNF688
ZNF774
ZNF829
ZRANB1
ZZZ3
Entrez ID
147687
64170
HPRD ID
18341
06236
Ensembl ID
ENSG00000173480
ENSG00000187796
Uniprot IDs
M0R230
Q8TAU3
A0A024R8F1
Q9H257
PDB IDs
6E25
6E26
6E27
6E28
6N2M
6N2P
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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