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STX4 and STX12
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
STX4
STX12
Description
syntaxin 4
syntaxin 12
Image
No pdb structure
GO Annotations
Cellular Component
Storage Vacuole
Extracellular Space
Endosome
Vacuole
Trans-Golgi Network
Cytosol
Plasma Membrane
Synaptic Vesicle
Cell Surface
Endomembrane System
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Lamellipodium
Phagocytic Vesicle Membrane
SNARE Complex
Myelin Sheath Adaxonal Region
Somatodendritic Compartment
Specific Granule
Dendritic Spine
Lateral Loop
Synapse
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Golgi Membrane
Phagophore Assembly Site
Nucleoplasm
Golgi Apparatus
Synaptic Vesicle
Endomembrane System
Integral Component Of Membrane
Integral Component Of Synaptic Vesicle Membrane
BLOC-1 Complex
SNARE Complex
Early Endosome Membrane
Vesicle
Intracellular Membrane-bounded Organelle
Membrane Raft
Phagocytic Vesicle
Recycling Endosome Membrane
Postsynaptic Recycling Endosome
Molecular Function
SNARE Binding
SNAP Receptor Activity
Protein Binding
Sphingomyelin Phosphodiesterase Activator Activity
SNARE Binding
SNAP Receptor Activity
Protein Binding
Biological Process
Positive Regulation Of Immunoglobulin Production
Intracellular Protein Transport
Exocytosis
Post-Golgi Vesicle-mediated Transport
Vesicle Fusion
Positive Regulation Of Cell Population Proliferation
Regulation Of Exocytosis
Cytokine-mediated Signaling Pathway
Positive Regulation Of Cell Migration
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Cellular Response To Oxidative Stress
SNARE Complex Assembly
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Catalytic Activity
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of Cell Adhesion
Vesicle Docking
Organelle Fusion
Positive Regulation Of Chemotaxis
Long-term Synaptic Potentiation
Cellular Response To Interferon-gamma
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein Localization To Plasma Membrane
Cornified Envelope Assembly
Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Positive Regulation Of Protein Localization To Cell Surface
Autophagosome Assembly
Intracellular Protein Transport
Vesicle Fusion
Cholesterol Efflux
Vesicle Docking
Protein Stabilization
Pathways
Disinhibition of SNARE formation
ER-Phagosome pathway
Translocation of SLC2A4 (GLUT4) to the plasma membrane
trans-Golgi Network Vesicle Budding
Other interleukin signaling
Drugs
Diseases
GWAS
Response to metformin (IC50) (
28173075
)
Triglyceride levels (
32203549
)
Interacting Genes
72 interacting genes:
ABI2
ACTB
ANKRD46
BET1
CYBRD1
DLG1
DNAJC5
EMD
FAXDC2
GIMAP5
GOSR2
GPR152
ITSN2
LLGL1
LMNA
NAPA
NAPB
NSF
PLP1
PSMA3
RAB11A
RAB4A
RAB5A
RNF4
SCRIB
SEC22A
SEC22B
SEPTIN5
SERP1
SGPL1
SH3GLB2
SNAP23
SNAP25
SNAP29
SNAP47
STX10
STX11
STX12
STX16
STX1A
STX1B
STX2
STX3
STX5
STX6
STX7
STX8
STXBP3
STXBP4
STXBP5
STXBP6
SYT1
SYT4
SYT7
TCEANC
TMEM199
TMEM203
TRAF3IP3
TXLNA
TXLNB
TXLNG
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAMP7
VAMP8
VAPB
VTI1B
ZFPL1
43 interacting genes:
AQP6
AQP8
BCL2L13
BLOC1S6
CD79A
CISD2
DNAJC5
DTX2
EBP
EEA1
EPB42
ERGIC3
FCER1G
GORAB
HOMER1
KASH5
LEPROTL1
LMNA
MFSD6
MMGT1
NAPA
NEMP1
NSG1
PDZK1IP1
PLPPR2
RIC3
SEC11C
SLC10A6
SLC66A2
SNAP23
SNAP25
SNAP29
STX1A
STX2
STX4
STXBP5L
TIMMDC1
TLCD4
TMEM14B
TMEM167B
TMEM31
TMEM86B
TMX2
Entrez ID
6810
23673
HPRD ID
01722
06059
Ensembl ID
ENSG00000103496
ENSG00000117758
Uniprot IDs
B7Z425
Q12846
Q86Y82
PDB IDs
2DNX
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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