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STX4 and SCRIB
Data Source:
HPRD
(in vivo)
STX4
SCRIB
Description
syntaxin 4
scribble planar cell polarity protein
Image
No pdb structure
GO Annotations
Cellular Component
Storage Vacuole
Extracellular Space
Endosome
Vacuole
Trans-Golgi Network
Cytosol
Plasma Membrane
Synaptic Vesicle
Cell Surface
Endomembrane System
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Lamellipodium
Phagocytic Vesicle Membrane
SNARE Complex
Myelin Sheath Adaxonal Region
Somatodendritic Compartment
Specific Granule
Dendritic Spine
Lateral Loop
Synapse
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Immunological Synapse
Nucleoplasm
Plasma Membrane
Cell-cell Junction
Adherens Junction
Ionotropic Glutamate Receptor Complex
Postsynaptic Density
Basolateral Plasma Membrane
Lamellipodium
Cell Junction
Cell Leading Edge
Scrib-APC-beta-catenin Complex
Presynaptic Membrane
Postsynaptic Membrane
Extracellular Exosome
Molecular Function
SNARE Binding
SNAP Receptor Activity
Protein Binding
Sphingomyelin Phosphodiesterase Activator Activity
Protein Binding
Cadherin Binding
Biological Process
Positive Regulation Of Immunoglobulin Production
Intracellular Protein Transport
Exocytosis
Post-Golgi Vesicle-mediated Transport
Vesicle Fusion
Positive Regulation Of Cell Population Proliferation
Regulation Of Exocytosis
Cytokine-mediated Signaling Pathway
Positive Regulation Of Cell Migration
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Cellular Response To Oxidative Stress
SNARE Complex Assembly
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Catalytic Activity
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of Cell Adhesion
Vesicle Docking
Organelle Fusion
Positive Regulation Of Chemotaxis
Long-term Synaptic Potentiation
Cellular Response To Interferon-gamma
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein Localization To Plasma Membrane
Cornified Envelope Assembly
Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Positive Regulation Of Protein Localization To Cell Surface
Establishment Of T Cell Polarity
Neural Tube Closure
Positive Regulation Of Receptor Recycling
Cell Population Proliferation
Embryo Development
Cell Migration
Mitigation Of Host Immune Response By Virus
Polarized Epithelial Cell Differentiation
Positive Regulation Of Interferon-gamma Production
Establishment Of Apical/basal Cell Polarity
Suppression By Virus Of Host STAT1 Activity
Suppression By Virus Of Host STAT2 Activity
Positive Regulation Of Apoptotic Process
Receptor Clustering
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Activated T Cell Proliferation
Positive Chemotaxis
Apoptotic Process Involved In Morphogenesis
Mammary Gland Duct Morphogenesis
Protein Localization To Adherens Junction
Activation Of GTPase Activity
Receptor Localization To Synapse
Cell-cell Adhesion
Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome
Pathways
Disinhibition of SNARE formation
ER-Phagosome pathway
Translocation of SLC2A4 (GLUT4) to the plasma membrane
trans-Golgi Network Vesicle Budding
Other interleukin signaling
Asymmetric localization of PCP proteins
Drugs
Diseases
GWAS
Response to metformin (IC50) (
28173075
)
Triglyceride levels (
32203549
)
Menarche (age at onset) (
25231870
)
Interacting Genes
72 interacting genes:
ABI2
ACTB
ANKRD46
BET1
CYBRD1
DLG1
DNAJC5
EMD
FAXDC2
GIMAP5
GOSR2
GPR152
ITSN2
LLGL1
LMNA
NAPA
NAPB
NSF
PLP1
PSMA3
RAB11A
RAB4A
RAB5A
RNF4
SCRIB
SEC22A
SEC22B
SEPTIN5
SERP1
SGPL1
SH3GLB2
SNAP23
SNAP25
SNAP29
SNAP47
STX10
STX11
STX12
STX16
STX1A
STX1B
STX2
STX3
STX5
STX6
STX7
STX8
STXBP3
STXBP4
STXBP5
STXBP6
SYT1
SYT4
SYT7
TCEANC
TMEM199
TMEM203
TRAF3IP3
TXLNA
TXLNB
TXLNG
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAMP7
VAMP8
VAPB
VTI1B
ZFPL1
12 interacting genes:
APC
ARHGEF7
C5AR2
EXOSC10
LPP
MAPK3
PRKCA
STX4
TJP2
TRIP6
TSHR
UBE3A
Entrez ID
6810
23513
HPRD ID
01722
06984
Ensembl ID
ENSG00000103496
ENSG00000180900
Uniprot IDs
B7Z425
Q12846
A0A0G2JNZ2
A0A0G2JPP5
A0PJK8
Q14160
PDB IDs
1UJU
1WHA
1X5Q
2W4F
4WYT
4WYU
5VWC
5VWI
5VWK
6EEY
6ESP
6MS1
6MTU
6MTV
6MYE
6MYF
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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