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STX4 and RAB4A
Data Source:
HPRD
(in vitro, in vivo)
STX4
RAB4A
Description
syntaxin 4
RAB4A, member RAS oncogene family
Image
No pdb structure
GO Annotations
Cellular Component
Storage Vacuole
Extracellular Space
Endosome
Vacuole
Trans-Golgi Network
Cytosol
Plasma Membrane
Synaptic Vesicle
Cell Surface
Endomembrane System
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Lamellipodium
Phagocytic Vesicle Membrane
SNARE Complex
Myelin Sheath Adaxonal Region
Somatodendritic Compartment
Specific Granule
Dendritic Spine
Lateral Loop
Synapse
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Endosome
Cytosol
Plasma Membrane
Cytoplasmic Vesicle Membrane
Early Endosome Membrane
Vesicle
Insulin-responsive Compartment
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Recycling Endosome Membrane
Extracellular Exosome
Postsynaptic Recycling Endosome
Anchored Component Of Synaptic Vesicle Membrane
Molecular Function
SNARE Binding
SNAP Receptor Activity
Protein Binding
Sphingomyelin Phosphodiesterase Activator Activity
ATPase Activator Activity
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Syntaxin Binding
Ionotropic Glutamate Receptor Binding
ATPase Binding
Biological Process
Positive Regulation Of Immunoglobulin Production
Intracellular Protein Transport
Exocytosis
Post-Golgi Vesicle-mediated Transport
Vesicle Fusion
Positive Regulation Of Cell Population Proliferation
Regulation Of Exocytosis
Cytokine-mediated Signaling Pathway
Positive Regulation Of Cell Migration
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Cellular Response To Oxidative Stress
SNARE Complex Assembly
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Catalytic Activity
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of Cell Adhesion
Vesicle Docking
Organelle Fusion
Positive Regulation Of Chemotaxis
Long-term Synaptic Potentiation
Cellular Response To Interferon-gamma
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein Localization To Plasma Membrane
Cornified Envelope Assembly
Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Positive Regulation Of Protein Localization To Cell Surface
Phosphatidylinositol Biosynthetic Process
Protein Transport
Antigen Processing And Presentation
Regulation Of Endocytosis
Rab Protein Signal Transduction
Positive Regulation Of ATPase Activity
Pathways
Disinhibition of SNARE formation
ER-Phagosome pathway
Translocation of SLC2A4 (GLUT4) to the plasma membrane
trans-Golgi Network Vesicle Budding
Other interleukin signaling
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Synthesis of PIPs at the plasma membrane
TBC/RABGAPs
RAB geranylgeranylation
MET receptor recycling
Drugs
Diseases
GWAS
Response to metformin (IC50) (
28173075
)
Triglyceride levels (
32203549
)
Aging (
22773346
)
Leukoderma in response to rhododendrol (
32558222
)
Mean arterial pressure (alcohol consumption interaction) (
24376456
)
Mercury levels (
26025379
)
Response to antidepressants in depression (
27622933
)
Interacting Genes
72 interacting genes:
ABI2
ACTB
ANKRD46
BET1
CYBRD1
DLG1
DNAJC5
EMD
FAXDC2
GIMAP5
GOSR2
GPR152
ITSN2
LLGL1
LMNA
NAPA
NAPB
NSF
PLP1
PSMA3
RAB11A
RAB4A
RAB5A
RNF4
SCRIB
SEC22A
SEC22B
SEPTIN5
SERP1
SGPL1
SH3GLB2
SNAP23
SNAP25
SNAP29
SNAP47
STX10
STX11
STX12
STX16
STX1A
STX1B
STX2
STX3
STX5
STX6
STX7
STX8
STXBP3
STXBP4
STXBP5
STXBP6
SYT1
SYT4
SYT7
TCEANC
TMEM199
TMEM203
TRAF3IP3
TXLNA
TXLNB
TXLNG
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAMP7
VAMP8
VAPB
VTI1B
ZFPL1
33 interacting genes:
ACTB
APBB3
CD2AP
CDK1
CHM
DYNC1LI1
DYNLL1
EXOC5
FAM71C
GDI2
GRIPAP1
HACE1
IDH3A
KCTD7
KIF3B
MAPK3
PIN1
PRKCI
PTTG1IP
RAB11FIP1
RAB7A
RABAC1
RABEP1
RABEP2
RABGAP1
RABGEF1
RBSN
RUFY1
SOD2
STX4
TP53
VPS52
ZNF830
Entrez ID
6810
5867
HPRD ID
01722
01541
Ensembl ID
ENSG00000103496
ENSG00000168118
Uniprot IDs
B7Z425
Q12846
A0A024R3U9
A0A087WYT5
P20338
PDB IDs
1YU9
1Z0K
2BMD
2BME
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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