STX12 and TMEM86B

Data Source:
BioGRID (two hybrid)

		STX12	TMEM86B
Description		syntaxin 12	transmembrane protein 86B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Phagophore Assembly Site Nucleoplasm Golgi Apparatus Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome	Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Protein Binding Ether Hydrolase Activity Identical Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization	Phosphatidylcholine Acyl-chain Remodeling Ether Lipid Metabolic Process
Pathways			Acyl chain remodelling of PC
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494) Phosphatidylethanolamine-ether levels ( 31551469) Systemic lupus erythematosus ( 33536424 28714469)
Interacting Genes		43 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2	105 interacting genes: AQP6 ARL13B ARL6IP6 ASGR2 BCL2L13 BIK BMP10 C2CD2L CCDC167 CCDC34 CCL4 CD53 CD79A CLRN1 CYB5B DHRSX DNAJC30 EBP ERGIC3 ERP29 EVI2B F11R FAM209A FAXDC2 FKBP7 FXYD6 GJA1 GJA4 GJA8 GOLM1 GPR37L1 GPX8 GUCA2A HIBADH HSD17B13 IER3IP1 IFITM3 KIR2DL3 LAPTM4B LIME1 LSS LY6D MARCHF2 MFF MGST3 MMGT1 MS4A14 MSMO1 MUC1 NDUFAF1 NEMP1 NINJ2 ORMDL2 OTULINL PEX11G PGRMC2 PIGF PLN PSCA PTPN1 PTPN9 RHBDD1 RHOT2 RPRM RTP2 SEC22B SERINC2 SFRP1 SFT2D1 SFXN5 SLC10A6 SLC29A2 SLC35G2 SLC39A9 SMIM1 SNORC SSMEM1 STOM STX12 STX6 STX8 TEX29 THAP4 THBD TIMM23 TMEM106A TMEM107 TMEM120A TMEM14A TMEM14C TMEM203 TMEM237 TMEM248 TMEM52B TMEM60 TMPRSS2 TMX2 TREX1 TSNARE1 USE1 VAMP2 VAMP3 VAMP5 VAPA ZDHHC22
Entrez ID		23673	255043
HPRD ID		06059	14540
Ensembl ID		ENSG00000117758	ENSG00000180089
Uniprot IDs		Q86Y82	Q8N661
PDB IDs		2DNX
Enriched GO Terms of Interacting Partners?
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