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SRC and PTPN1
Data Source:
BioGRID
(affinity chromatography technology, enzymatic study)
HPRD
(in vivo, in vitro)
SRC
PTPN1
Description
SRC proto-oncogene, non-receptor tyrosine kinase
protein tyrosine phosphatase non-receptor type 1
Image
GO Annotations
Cellular Component
Podosome
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Lysosome
Late Endosome
Cytosol
Actin Filament
Plasma Membrane
Caveola
Focal Adhesion
Postsynaptic Density
Cell Junction
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ruffle Membrane
Neuron Projection
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Glutamatergic Synapse
Postsynaptic Specialization, Intracellular Component
Mitochondrial Matrix
Early Endosome
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Mitochondrial Crista
Protein-containing Complex
Sorting Endosome
Cytoplasmic Side Of Endoplasmic Reticulum Membrane
Molecular Function
Protein Kinase Activity
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein Kinase C Binding
Signaling Receptor Binding
Insulin Receptor Binding
Integrin Binding
Protein Binding
ATP Binding
Protein C-terminus Binding
Kinase Activity
Enzyme Binding
Kinase Binding
Heme Binding
Estrogen Receptor Binding
Ubiquitin Protein Ligase Binding
SH2 Domain Binding
Ion Channel Binding
Cadherin Binding
Ephrin Receptor Binding
ATPase Binding
Phosphoprotein Binding
BMP Receptor Binding
Growth Factor Receptor Binding
Connexin Binding
Scaffold Protein Binding
RNA Binding
Protein Tyrosine Phosphatase Activity
Insulin Receptor Binding
Protein Binding
Zinc Ion Binding
Enzyme Binding
Protein Kinase Binding
Receptor Tyrosine Kinase Binding
Cadherin Binding
Ephrin Receptor Binding
Protein Phosphatase 2A Binding
Biological Process
Primary Ovarian Follicle Growth
Stimulatory C-type Lectin Receptor Signaling Pathway
Cell Cycle
Cell Adhesion
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Signal Complex Assembly
Epidermal Growth Factor Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Axon Guidance
Cell Population Proliferation
Response To Mechanical Stimulus
Response To Virus
Response To Acidic PH
Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Glucose Metabolic Process
Positive Regulation Of Protein Processing
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Smooth Muscle Cell Migration
Viral Process
Macroautophagy
Peptidyl-serine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Regulation Of Cell-cell Adhesion
Cell Differentiation
Platelet Activation
Forebrain Development
T Cell Costimulation
Negative Regulation Of Protein-containing Complex Assembly
Protein Destabilization
Response To Nutrient Levels
Positive Regulation Of Protein Autophosphorylation
Activation Of Protein Kinase B Activity
Negative Regulation Of Telomere Maintenance Via Telomerase
Cellular Response To Insulin Stimulus
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Positive Regulation Of Integrin Activation
Adherens Junction Organization
Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Dephosphorylation
Intracellular Signal Transduction
Entry Of Bacterium Into Host Cell
Osteoclast Development
Cellular Response To Platelet-derived Growth Factor Stimulus
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
ERBB2 Signaling Pathway
Odontogenesis
Response To Drug
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Vascular Permeability
Stress Fiber Assembly
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Protein Binding
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Transcytosis
Innate Immune Response
Regulation Of Bone Resorption
Bone Resorption
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Notch Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Insulin Receptor Signaling Pathway
Protein Autophosphorylation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Focal Adhesion Assembly
Oogenesis
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Progesterone Receptor Signaling Pathway
Leukocyte Migration
Positive Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Transport
Response To Mineralocorticoid
Response To Electrical Stimulus
Negative Regulation Of Focal Adhesion Assembly
Positive Regulation Of Protein Kinase B Signaling
Negative Regulation Of Mitochondrial Depolarization
Negative Regulation Of Telomerase Activity
Uterus Development
Branching Involved In Mammary Gland Duct Morphogenesis
Regulation Of Cell Projection Assembly
Intestinal Epithelial Cell Development
Interleukin-6-mediated Signaling Pathway
Cellular Response To Hydrogen Peroxide
Positive Regulation Of ERK1 And ERK2 Cascade
Response To Interleukin-1
Cellular Response To Lipopolysaccharide
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Progesterone Stimulus
Cellular Response To Fatty Acid
Cellular Response To Hypoxia
Cellular Response To Fluid Shear Stress
Positive Regulation Of Podosome Assembly
Positive Regulation Of Protein Serine/threonine Kinase Activity
Angiotensin-activated Signaling Pathway Involved In Heart Process
Positive Regulation Of Canonical Wnt Signaling Pathway
Cell-cell Adhesion
Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity
Positive Regulation Of Ovarian Follicle Development
Positive Regulation Of Lamellipodium Morphogenesis
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Regulation Of Early Endosome To Late Endosome Transport
Negative Regulation Of Anoikis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Caveolin-mediated Endocytosis
Protein Dephosphorylation
Activation Of JUN Kinase Activity
Insulin Receptor Signaling Pathway
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Regulation Of Endocytosis
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Endoplasmic Reticulum Unfolded Protein Response
Actin Cytoskeleton Reorganization
Regulation Of Intracellular Protein Transport
Cellular Response To Unfolded Protein
Peptidyl-tyrosine Dephosphorylation
Platelet-derived Growth Factor Receptor-beta Signaling Pathway
IRE1-mediated Unfolded Protein Response
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Type I Interferon-mediated Signaling Pathway
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of ERK1 And ERK2 Cascade
Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of IRE1-mediated Unfolded Protein Response
Negative Regulation Of PERK-mediated Unfolded Protein Response
Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity
Positive Regulation Of Receptor Catabolic Process
Pathways
Signaling by ERBB2
Nuclear signaling by ERBB4
Downregulation of ERBB4 signaling
PIP3 activates AKT signaling
GAB1 signalosome
Downstream signal transduction
Constitutive Signaling by Aberrant PI3K in Cancer
Integrin signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
DCC mediated attractive signaling
DCC mediated attractive signaling
Netrin mediated repulsion signals
Regulation of commissural axon pathfinding by SLIT and ROBO
RAF activation
MAP2K and MAPK activation
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
MET activates PTK2 signaling
InlA-mediated entry of Listeria monocytogenes into host cells
Regulation of RUNX1 Expression and Activity
RUNX2 regulates osteoblast differentiation
Regulation of RUNX3 expression and activity
Extra-nuclear estrogen signaling
Activated NTRK2 signals through FYN
Activated NTRK3 signals through PI3K
Activated NTRK3 signals through PI3K
Long-term potentiation
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
Integrin signaling
Negative regulation of MET activity
Regulation of IFNG signaling
PTK6 Down-Regulation
MECP2 regulates neuronal receptors and channels
Regulation of IFNA signaling
Growth hormone receptor signaling
Growth hormone receptor signaling
Drugs
Dasatinib
RU84687
RU79256
N6-Benzyl Adenosine-5'-Diphosphate
RU85493
RU78262
Phosphonotyrosine
Malonic acid
RU83876
RU90395
RU79072
RU78783
1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
PASBN
2-[4-[(Z)-2-Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]prop-1-enyl]-2-formylphenyl]acetic acid
PAS219
DPI59
RU82197
Phenylphosphate
RU78300
RU79073
RU82209
ISO24
RU85053
RU78299
Oxalic Acid
RU78191
Citric acid
Paratoulene phosphate
4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE
Purvalanol A
XL228
Tirbanibulin
Bosutinib
1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea
1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea
3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL
PD-168393
[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile
PP-121
1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE
N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE
(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide
Ponatinib
Nintedanib
Fostamatinib
3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid
2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid
5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic acid
2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Thiopyran-3-Carboxylic Acid
3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid (4-Sulfamoyl-Phenyl)-Amide
[[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid,
{4-[(2S)-2-({[(1S)-1-Carboxy-2-phenylethyl]carbamoyl}amino)-3-oxo-3-(pentylamino)propyl]phenoxy}malonic acid
Compound 19
3-(4-{2-[2-(2-bromo-acetylamino)-ethyldisulfanyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-pyrazine-2-carboxylic acid
2-(Oxalyl-Amino)-Benzoic Acid
{[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene)]}Bis(Phosphonic Acid)
Novo Nordisk a/S Compound
N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide
7-(1,1-Dioxo-1h-Benzo[D]Isothiazol-3-Yloxymethyl)-2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid
PNU177836
2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid
{[7-(Difluoro-Phosphono-Methyl)-Naphthalen-2-Yl]-Difluoro-Methyl}-Phosphonic Acid
3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phenyl]-Amide
(4S)-5-[[(2S)-1-[[(2S)-1-Amino-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-4-benzamido-5-oxopentanoic acid
4-[[(2S)-1-[[6-[(1-Amino-1-oxo-3-sulfanylpropan-2-yl)amino]-6-oxohexyl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[[2-[4-[difluoro(phosphono)methyl]phenyl]acetyl]amino]-4-oxobutanoic acid
L-cysteic acid
2-(Oxalyl-Amino)-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid
4-Carbamoyl-4-{[6-(Difluoro-Phosphono-Methyl)-Naphthalene-2-Carbonyl]-Amino}-Butyric Acid
Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid
6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid
2-[{4-[(2S)-2-{[(Allyloxy)carbonyl]amino}-3-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-3-oxopropyl]phenyl}(carboxycarbonyl)amino]benzoic acid
3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide
[(4-{4-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Butyl}-Phenyl)-Difluoro-Methyl]-Phosphonic Acid
{4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide
1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID
ISIS 113715
Trodusquemine
Ertiprotafib
4-BROMO-3-(CARBOXYMETHOXY)-5-[3-(CYCLOHEXYLAMINO)PHENYL]THIOPHENE-2-CARBOXYLIC ACID
[(3S)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid
4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
4-BROMO-3-(CARBOXYMETHOXY)-5-(4-HYDROXYPHENYL)THIOPHENE-2-CARBOXYLIC ACID
[{2-bromo-4-[(2R)-3-oxo-2,3-diphenylpropyl]phenyl}(difluoro)methyl]phosphonic acid
5-[3-(BENZYLAMINO)PHENYL]-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID
2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID
3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN
N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE
[(3R)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid
5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE
5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID
ISOTHIAZOLIDINONE ANALOG
4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid
p-Benzoyl-L-phenylalanine
6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBOXYLIC ACID
(3R)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER
5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE
(4-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-methoxy-3-oxopropyl}phenyl)methaneseleninic acid
Diseases
GWAS
Retinopathy in non-diabetics (
23393555
)
Rheumatoid arthritis (
30891314
)
Squamous cell carcinoma (
26908436
)
Basophil count (
32888494
)
Colorectal cancer (
30529582
31826910
)
Colorectal cancer or advanced adenoma (
30510241
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Intraocular pressure (
29617998
29785010
31959993
30054594
)
Lymphocyte percentage of white cells (
32888494
)
Thyroid stimulating hormone levels (
30843173
)
Vitiligo (
27723757
)
Interacting Genes
300 interacting genes:
ABL1
ACTN1
ADAM12
ADAM15
ADRB2
ADRB3
AFAP1
AFAP1L2
AGAP1
AKT1
ALDOB
ANKRD11
ANXA1
ANXA2
ANXA7
AR
ARHGAP1
ARHGAP17
ARHGAP32
ARHGAP35
ARR3
ASAP1
ATG9A
ATP2B4
AXL
BAAT
BCAR1
BCCIP
BCR
BMX
CA3
CASP8
CAV1
CAV2
CBL
CBLC
CCDC180
CCNA1
CD2AP
CD33
CD36
CD44
CD46
CD59
CDC25A
CDC37
CDCP1
CDH5
CDK1
CDK5
CDKN1B
CEACAM1
CEACAM3
CFL1
CHUK
CLTC
CNTNAP1
COASY
CORO7
CRMP1
CSK
CTNNB1
CTNND1
CTSV
CTTN
DAB1
DAB2
DAG1
DAPP1
DDR2
DGKA
DGKZ
DLG4
DNM1
DNM2
DOK1
DOK2
DOK4
EFNA5
EFNB1
EFNB2
EFS
EGFR
EGLN1
EMD
ENO1
EPHA3
EPHA4
EPHB2
EPS8
ERBB2
ERBB3
ERBB4
ERRFI1
ESR1
ESR2
ETS1
ETS2
EVL
FANCC
FARP2
FASLG
FBP2
FBXO5
FGR
FHIT
FLNA
FLT3
FOXO1
FRS2
FYB1
FZR1
GAB1
GAB2
GAB3
GALNT12
GFAP
GIT1
GJA1
GJB1
GRB10
GRB2
GRIN2A
GRIN2B
GRK2
GTF2I
GUCY2C
HDAC3
HEMGN
HLA-A
HLA-B
HNF1A
HNRNPK
HRAS
HSP90AA1
IGF1R
IKBKB
IKBKG
IL6R
INPPL1
INSR
ITGB3
ITK
JUP
KCNA5
KCNB1
KCNQ5
KDR
KHDRBS1
KIFAP3
KIT
LRP1
LYN
MAP2
MAP2K1
MAPK15
MAPK3
MAPK8IP3
MAPRE1
MAPT
MATK
MDM2
MED28
MET
MICAL1
MPZL1
MST1R
MT-ND2
MUC1
MYLK
NANS
NCOA6
NEDD4
NFKBIA
NMT1
NOS2
NPHS1
NR1I2
NR1I3
NR3C1
P2RY2
PAK2
PDCD6IP
PDE4D
PDE6G
PDGFRB
PDPK1
PECAM1
PELP1
PGR
PIK3R1
PIK3R3
PIP5K1C
PKD1
PLCG1
PLD1
PLD2
PLSCR1
PPARD
PPARGC1B
PPP2CB
PRKACA
PRKCA
PRKCD
PRKCE
PRKCH
PRKCI
PRKCZ
PRKD1
PROM1
PTK2
PTK2B
PTPA
PTPN1
PTPN11
PTPN18
PTPN2
PTPN21
PTPN6
PTPRA
PTPRC
PTPRE
PXN
RACK1
RAF1
RARA
RASA1
RASGRF1
RET
RGS16
RPL10
RPS6KA3
RPS6KB1
RPS6KB2
RXRA
SH2D3C
SH3BP1
SH3PXD2A
SHB
SHC1
SKAP1
SKAP2
SLC9A2
SMARCB1
SMARCE1
SNCA
SORBS1
SPTAN1
SRCIN1
SRF
SRPK2
STAP2
STAT1
STAT3
STAT5A
STAT5B
STAT6
STUB1
STX17
SYK
SYN1
TAMALIN
TERT
THRA
THRB
TIAM1
TMPO
TNFRSF11A
TNFRSF1A
TNK2
TP53
TRAF1
TRAF3
TRAF6
TRAT1
TRIM50
TRIM7
TRIP10
TRIP6
TRMO
TRPC6
TRPV4
TUB
TXK
TYRO3
USP8
VCL
VDR
VIL1
WAS
WASL
WBP11
WWOX
XPA
YTHDC1
YWHAB
YWHAE
YWHAG
YWHAH
ZNF189
66 interacting genes:
ACTN1
AGR3
AKT1
AQP6
ASS1
BCAR1
BCAS3
BCR
CAPN2
CASC3
CASZ1
CAV1
CCL5
CDH13
CDH2
CDK1
CLK1
CLK2
COP1
CRK
CSNK2A1
CSNK2A2
CTNNB1
DIRAS3
EGFR
ELOVL4
ESR1
FGFR1
GHR
GLRX
GRB2
GSK3B
IGF1R
INSR
IRS1
JAK2
KLK7
LAT
LRATD2
LTK
MAPK1
MRC2
NFKBIA
NTRK1
NTRK2
NTRK3
PDGFRB
PIAS1
PIGP
PIN1
RHOBTB2
RRAS2
SNAI1
SRC
STAM2
STAT3
STAT5A
STAT5B
THRSP
TIMMDC1
TMEM31
TMEM41A
TMEM86B
TRPV6
TYK2
VPS45
Entrez ID
6714
5770
HPRD ID
01819
01477
Ensembl ID
ENSG00000197122
ENSG00000196396
Uniprot IDs
P12931
A8K3M3
B4DSN5
P18031
PDB IDs
1A07
1A08
1A09
1A1A
1A1B
1A1C
1A1E
1FMK
1HCS
1HCT
1KSW
1O41
1O42
1O43
1O44
1O45
1O46
1O47
1O48
1O49
1O4A
1O4B
1O4C
1O4D
1O4E
1O4F
1O4G
1O4H
1O4I
1O4J
1O4K
1O4L
1O4M
1O4N
1O4O
1O4P
1O4Q
1O4R
1SHD
1Y57
1YI6
1YOJ
1YOL
1YOM
2BDF
2BDJ
2H8H
2SRC
3VRO
3ZMP
3ZMQ
4F59
4F5A
4F5B
4HXJ
4K11
4MXO
4MXX
4MXY
4MXZ
6ATE
6C4S
6E6E
6EHJ
1A5Y
1AAX
1BZC
1BZH
1BZJ
1C83
1C84
1C85
1C86
1C87
1C88
1ECV
1EEN
1EEO
1G1F
1G1G
1G1H
1G7F
1G7G
1GFY
1I57
1JF7
1KAK
1KAV
1L8G
1LQF
1NL9
1NNY
1NO6
1NWE
1NWL
1NZ7
1OEM
1OEO
1OES
1OET
1OEU
1OEV
1ONY
1ONZ
1PA1
1PH0
1PTT
1PTU
1PTV
1PTY
1PXH
1PYN
1Q1M
1Q6J
1Q6M
1Q6N
1Q6P
1Q6S
1Q6T
1QXK
1SUG
1T48
1T49
1T4J
1WAX
1XBO
2AZR
2B07
2B4S
2BGD
2BGE
2CM2
2CM3
2CM7
2CM8
2CMA
2CMB
2CMC
2CNE
2CNF
2CNG
2CNH
2CNI
2F6F
2F6T
2F6V
2F6W
2F6Y
2F6Z
2F70
2F71
2FJM
2FJN
2H4G
2H4K
2HB1
2HNP
2HNQ
2NT7
2NTA
2QBP
2QBQ
2QBR
2QBS
2VEU
2VEV
2VEW
2VEX
2VEY
2ZMM
2ZN7
3A5J
3A5K
3CWE
3D9C
3EAX
3EB1
3EU0
3I7Z
3I80
3QKP
3QKQ
3SME
3ZMP
3ZMQ
3ZV2
4BJO
4I8N
4QAH
4QAP
4QBE
4QBW
4Y14
4ZRT
5K9V
5K9W
5KA0
5KA1
5KA2
5KA3
5KA4
5KA7
5KA8
5KA9
5KAA
5KAB
5KAC
5KAD
5QDE
5QDF
5QDG
5QDH
5QDI
5QDJ
5QDK
5QDL
5QDM
5QDN
5QDO
5QDP
5QDQ
5QDR
5QDS
5QDT
5QDU
5QDV
5QDW
5QDX
5QDY
5QDZ
5QE0
5QE1
5QE2
5QE3
5QE4
5QE5
5QE6
5QE7
5QE8
5QE9
5QEA
5QEB
5QEC
5QED
5QEE
5QEF
5QEG
5QEH
5QEI
5QEJ
5QEK
5QEL
5QEM
5QEN
5QEO
5QEP
5QEQ
5QER
5QES
5QET
5QEU
5QEV
5QEW
5QEX
5QEY
5QEZ
5QF0
5QF1
5QF2
5QF3
5QF4
5QF5
5QF6
5QF7
5QF8
5QF9
5QFA
5QFB
5QFC
5QFD
5QFE
5QFF
5QFG
5QFH
5QFI
5QFJ
5QFK
5QFL
5QFM
5QFN
5QFO
5QFP
5QFQ
5QFR
5QFS
5QFT
5QFU
5QFV
5QFW
5QFX
5QFY
5QFZ
5QG0
5QG1
5QG2
5QG3
5QG4
5QG5
5QG6
5QG7
5QG8
5QG9
5QGA
5QGB
5QGC
5QGD
5QGE
5QGF
5T19
6B8E
6B8T
6B8X
6B8Z
6B90
6B95
6BAI
6CWU
6CWV
6NTP
6OL4
6OLQ
6OLV
6OMY
6PFW
6PG0
6PGT
6PHA
6PHS
6PM8
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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