SRC and HSP90AA1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		SRC	HSP90AA1
Description		SRC proto-oncogene, non-receptor tyrosine kinase	heat shock protein 90 alpha family class A member 1
Image
GO Annotations	Cellular Component	Podosome Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Lysosome Late Endosome Cytosol Actin Filament Plasma Membrane Caveola Focal Adhesion Postsynaptic Density Cell Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Ruffle Membrane Neuron Projection Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Glutamatergic Synapse Postsynaptic Specialization, Intracellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Protein-containing Complex Secretory Granule Lumen Melanosome Neuronal Cell Body Lysosomal Lumen Myelin Sheath Dendritic Growth Cone Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Exosome Endocytic Vesicle Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Kinase C Binding Signaling Receptor Binding Insulin Receptor Binding Integrin Binding Protein Binding ATP Binding Protein C-terminus Binding Kinase Activity Enzyme Binding Kinase Binding Heme Binding Estrogen Receptor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding Ion Channel Binding Cadherin Binding Ephrin Receptor Binding ATPase Binding Phosphoprotein Binding BMP Receptor Binding Growth Factor Receptor Binding Connexin Binding Scaffold Protein Binding	RNA Binding Protein Binding ATP Binding ATPase Activity MHC Class II Protein Complex Binding Nitric-oxide Synthase Regulator Activity TPR Domain Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Protein Folding Chaperone Tau Protein Binding GTPase Binding Unfolded Protein Binding DNA Polymerase Binding Scaffold Protein Binding Disordered Domain Specific Binding Protein Tyrosine Kinase Binding
	Biological Process	Primary Ovarian Follicle Growth Stimulatory C-type Lectin Receptor Signaling Pathway Cell Cycle Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signal Complex Assembly Epidermal Growth Factor Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Integrin-mediated Signaling Pathway Axon Guidance Cell Population Proliferation Response To Mechanical Stimulus Response To Virus Response To Acidic PH Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Protein Processing Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Smooth Muscle Cell Migration Viral Process Macroautophagy Peptidyl-serine Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of Cell-cell Adhesion Cell Differentiation Platelet Activation Forebrain Development T Cell Costimulation Negative Regulation Of Protein-containing Complex Assembly Protein Destabilization Response To Nutrient Levels Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase B Activity Negative Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Insulin Stimulus Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Integrin Activation Adherens Junction Organization Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Dephosphorylation Intracellular Signal Transduction Entry Of Bacterium Into Host Cell Osteoclast Development Cellular Response To Platelet-derived Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ERBB2 Signaling Pathway Odontogenesis Response To Drug Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Vascular Permeability Stress Fiber Assembly Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Protein Binding Positive Regulation Of MAP Kinase Activity Positive Regulation Of Phosphatidylinositol 3-kinase Activity Transcytosis Innate Immune Response Regulation Of Bone Resorption Bone Resorption Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Insulin Receptor Signaling Pathway Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Focal Adhesion Assembly Oogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Progesterone Receptor Signaling Pathway Leukocyte Migration Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Transport Response To Mineralocorticoid Response To Electrical Stimulus Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Mitochondrial Depolarization Negative Regulation Of Telomerase Activity Uterus Development Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Cell Projection Assembly Intestinal Epithelial Cell Development Interleukin-6-mediated Signaling Pathway Cellular Response To Hydrogen Peroxide Positive Regulation Of ERK1 And ERK2 Cascade Response To Interleukin-1 Cellular Response To Lipopolysaccharide Cellular Response To Peptide Hormone Stimulus Cellular Response To Progesterone Stimulus Cellular Response To Fatty Acid Cellular Response To Hypoxia Cellular Response To Fluid Shear Stress Positive Regulation Of Podosome Assembly Positive Regulation Of Protein Serine/threonine Kinase Activity Angiotensin-activated Signaling Pathway Involved In Heart Process Positive Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Regulation Of Postsynaptic Neurotransmitter Receptor Activity Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Lamellipodium Morphogenesis Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Negative Regulation Of Anoikis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Caveolin-mediated Endocytosis	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Protein Folding Mitochondrial Transport Receptor-mediated Endocytosis Response To Unfolded Protein Telomere Maintenance Via Telomerase Response To Heat Response To Cold Regulation Of G2/M Transition Of Mitotic Cell Cycle Viral Process Cytokine-mediated Signaling Pathway Central Nervous System Neuron Axonogenesis Establishment Of Cell Polarity Regulation Of Protein Ubiquitination Positive Regulation Of Protein Polymerization Positive Regulation Of Interferon-beta Production Positive Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Heat Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ERBB2 Signaling Pathway Protein Refolding Regulation Of Apoptotic Process Regulation Of Protein-containing Complex Assembly Neutrophil Degranulation Protein Unfolding Protein Insertion Into Mitochondrial Outer Membrane Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Antibiotic Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Extension Protein Stabilization Regulation Of Nitric-oxide Synthase Activity Chaperone-mediated Protein Complex Assembly Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Telomerase Activity Chaperone-mediated Autophagy Ciliary Basal Body-plasma Membrane Docking Cellular Response To Virus Regulation Of Cellular Response To Heat Positive Regulation Of Tau-protein Kinase Activity Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Cellular Protein Localization Telomerase Holoenzyme Complex Assembly
Pathways		Signaling by ERBB2 Nuclear signaling by ERBB4 Downregulation of ERBB4 signaling PIP3 activates AKT signaling GAB1 signalosome Downstream signal transduction Constitutive Signaling by Aberrant PI3K in Cancer Integrin signaling GRB2:SOS provides linkage to MAPK signaling for Integrins p130Cas linkage to MAPK signaling for integrins G alpha (s) signalling events G alpha (i) signalling events G alpha (i) signalling events DCC mediated attractive signaling DCC mediated attractive signaling Netrin mediated repulsion signals Regulation of commissural axon pathfinding by SLIT and ROBO RAF activation MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling MET activates PTK2 signaling InlA-mediated entry of Listeria monocytogenes into host cells Regulation of RUNX1 Expression and Activity RUNX2 regulates osteoblast differentiation Regulation of RUNX3 expression and activity Extra-nuclear estrogen signaling Activated NTRK2 signals through FYN Activated NTRK3 signals through PI3K Activated NTRK3 signals through PI3K Long-term potentiation Signaling downstream of RAS mutants Signaling by RAF1 mutants	Signaling by ERBB2 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation vRNP Assembly Regulation of actin dynamics for phagocytic cup formation eNOS activation Regulation of PLK1 Activity at G2/M Transition Scavenging by Class F Receptors Scavenging by Class F Receptors HSP90 chaperone cycle for steroid hormone receptors (SHR) HSF1 activation Attenuation phase HSF1-dependent transactivation Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Sema3A PAK dependent Axon repulsion VEGFA-VEGFR2 Pathway VEGFA-VEGFR2 Pathway VEGFR2 mediated vascular permeability Uptake and function of diphtheria toxin PIWI-interacting RNA (piRNA) biogenesis Anchoring of the basal body to the plasma membrane Constitutive Signaling by EGFRvIII Regulation of necroptotic cell death Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Downregulation of ERBB2 signaling ESR-mediated signaling Extra-nuclear estrogen signaling RHOBTB2 GTPase cycle Estrogen-dependent gene expression Chaperone Mediated Autophagy Constitutive Signaling by Overexpressed ERBB2 Aggrephagy Drug-mediated inhibition of ERBB2 signaling Signaling by ERBB2 KD Mutants Resistance of ERBB2 KD mutants to trastuzumab Resistance of ERBB2 KD mutants to sapitinib Resistance of ERBB2 KD mutants to tesevatinib Resistance of ERBB2 KD mutants to neratinib Resistance of ERBB2 KD mutants to osimertinib Resistance of ERBB2 KD mutants to afatinib Resistance of ERBB2 KD mutants to AEE788 Resistance of ERBB2 KD mutants to lapatinib Signaling by ERBB2 ECD mutants Signaling by ERBB2 TMD/JMD mutants Drug resistance in ERBB2 TMD/JMD mutants Potential therapeutics for SARS
Drugs		Dasatinib RU84687 RU79256 N6-Benzyl Adenosine-5'-Diphosphate RU85493 RU78262 Phosphonotyrosine Malonic acid RU83876 RU90395 RU79072 RU78783 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine PASBN 2-[4-[(Z)-2-Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]prop-1-enyl]-2-formylphenyl]acetic acid PAS219 DPI59 RU82197 Phenylphosphate RU78300 RU79073 RU82209 ISO24 RU85053 RU78299 Oxalic Acid RU78191 Citric acid Paratoulene phosphate 4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE Purvalanol A XL228 Tirbanibulin Bosutinib 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL PD-168393 [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile PP-121 1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide Ponatinib Nintedanib Fostamatinib	Rifabutin Nedocromil 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine Geldanamycin 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine 4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine 9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine 4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine Quercetin 8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE Tanespimycin SNX-5422 N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE 2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE 3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol CCT-018159 4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine (5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- 4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol 2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine 4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine 3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE Copper Polaprezinc Alvespimycin
Diseases
GWAS		Retinopathy in non-diabetics ( 23393555) Rheumatoid arthritis ( 30891314) Squamous cell carcinoma ( 26908436)	Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
Interacting Genes		300 interacting genes: ABL1 ACTN1 ADAM12 ADAM15 ADRB2 ADRB3 AFAP1 AFAP1L2 AGAP1 AKT1 ALDOB ANKRD11 ANXA1 ANXA2 ANXA7 AR ARHGAP1 ARHGAP17 ARHGAP32 ARHGAP35 ARR3 ASAP1 ATG9A ATP2B4 AXL BAAT BCAR1 BCCIP BCR BMX CA3 CASP8 CAV1 CAV2 CBL CBLC CCDC180 CCNA1 CD2AP CD33 CD36 CD44 CD46 CD59 CDC25A CDC37 CDCP1 CDH5 CDK1 CDK5 CDKN1B CEACAM1 CEACAM3 CFL1 CHUK CLTC CNTNAP1 COASY CORO7 CRMP1 CSK CTNNB1 CTNND1 CTSV CTTN DAB1 DAB2 DAG1 DAPP1 DDR2 DGKA DGKZ DLG4 DNM1 DNM2 DOK1 DOK2 DOK4 EFNA5 EFNB1 EFNB2 EFS EGFR EGLN1 EMD ENO1 EPHA3 EPHA4 EPHB2 EPS8 ERBB2 ERBB3 ERBB4 ERRFI1 ESR1 ESR2 ETS1 ETS2 EVL FANCC FARP2 FASLG FBP2 FBXO5 FGR FHIT FLNA FLT3 FOXO1 FRS2 FYB1 FZR1 GAB1 GAB2 GAB3 GALNT12 GFAP GIT1 GJA1 GJB1 GRB10 GRB2 GRIN2A GRIN2B GRK2 GTF2I GUCY2C HDAC3 HEMGN HLA-A HLA-B HNF1A HNRNPK HRAS HSP90AA1 IGF1R IKBKB IKBKG IL6R INPPL1 INSR ITGB3 ITK JUP KCNA5 KCNB1 KCNQ5 KDR KHDRBS1 KIFAP3 KIT LRP1 LYN MAP2 MAP2K1 MAPK15 MAPK3 MAPK8IP3 MAPRE1 MAPT MATK MDM2 MED28 MET MICAL1 MPZL1 MST1R MT-ND2 MUC1 MYLK NANS NCOA6 NEDD4 NFKBIA NMT1 NOS2 NPHS1 NR1I2 NR1I3 NR3C1 P2RY2 PAK2 PDCD6IP PDE4D PDE6G PDGFRB PDPK1 PECAM1 PELP1 PGR PIK3R1 PIK3R3 PIP5K1C PKD1 PLCG1 PLD1 PLD2 PLSCR1 PPARD PPARGC1B PPP2CB PRKACA PRKCA PRKCD PRKCE PRKCH PRKCI PRKCZ PRKD1 PROM1 PTK2 PTK2B PTPA PTPN1 PTPN11 PTPN18 PTPN2 PTPN21 PTPN6 PTPRA PTPRC PTPRE PXN RACK1 RAF1 RARA RASA1 RASGRF1 RET RGS16 RPL10 RPS6KA3 RPS6KB1 RPS6KB2 RXRA SH2D3C SH3BP1 SH3PXD2A SHB SHC1 SKAP1 SKAP2 SLC9A2 SMARCB1 SMARCE1 SNCA SORBS1 SPTAN1 SRCIN1 SRF SRPK2 STAP2 STAT1 STAT3 STAT5A STAT5B STAT6 STUB1 STX17 SYK SYN1 TAMALIN TERT THRA THRB TIAM1 TMPO TNFRSF11A TNFRSF1A TNK2 TP53 TRAF1 TRAF3 TRAF6 TRAT1 TRIM50 TRIM7 TRIP10 TRIP6 TRMO TRPC6 TRPV4 TUB TXK TYRO3 USP8 VCL VDR VIL1 WAS WASL WBP11 WWOX XPA YTHDC1 YWHAB YWHAE YWHAG YWHAH ZNF189	158 interacting genes: AHR AHSA1 AHSA2P AIP AIPL1 AKT1 AKT2 APAF1 APOB AR ARNTL ASGR1 BIRC5 BRMS1 CACYBP CALM1 CDC37 CDC37L1 CDK4 CDK5R1 CDKN2A CERS2 CFTR CHEK1 CHORDC1 CHUK CKS1B CKS2 CRNKL1 CSNK2A1 CSNK2A2 DAP3 DNAJC7 EGFR EGLN1 EIF2AK1 EIF2AK2 EIF2AK3 EIF2S1 EPAS1 EPRS1 ERBB2 ERN1 ESR1 ESRRB FAM162A FANCA FANCC FKBP1A FKBP4 FKBP5 FKBP6 FLCN FNIP1 FYN GABARAPL1 GNA12 GSK3B GUCY1B1 GZMA HDAC6 HIF1A HIF3A HSF1 HSPA8 HTT IKBKB IKBKE IKBKG IP6K2 IRAK1 IRF3 ITGB1BP2 JUN KDR KEAP1 LCK LINC01554 LSM1 MAP3K14 MAP3K3 MAPK1 MAPT MIS12 MMP2 MS4A2 MTRNR2L1 MUC1 MYC MYOD1 NDRG1 NOS1 NOS3 NPAS2 NR2C2 NR3C1 NR3C2 NSL1 PABPN1 PAK1 PDPK1 PIM1 PMF1 PPARA PPARD PPID PPIL2 PPP5C PRKACA PRKCA PRKCD PRKDC PTGDS PTGES3 PTPRF RAD51 RAF1 RHOBTB2 RIPK1 RPAP3 RPS3 RPS3A RUNX1T1 SERPINB5 SGTA SIM1 SKP1 SLC2A4 SLC34A1 SMYD2 SMYD3 SNCA SRC ST13 STARD13 STAT3 STIP1 STUB1 SUGT1 SUMO2 SVIL TBK1 TERT TJP1 TNFRSF1A TOMM34 TOMM40 TOMM70 TP53 TTK TTR UBASH3A UBE2N UCHL1 UNC45A USP19 USP50 WASL
Entrez ID		6714	3320
HPRD ID		01819	00777
Ensembl ID		ENSG00000197122	ENSG00000080824
Uniprot IDs		P12931	K9JA46 P07900 Q86SX1
PDB IDs		1A07 1A08 1A09 1A1A 1A1B 1A1C 1A1E 1FMK 1HCS 1HCT 1KSW 1O41 1O42 1O43 1O44 1O45 1O46 1O47 1O48 1O49 1O4A 1O4B 1O4C 1O4D 1O4E 1O4F 1O4G 1O4H 1O4I 1O4J 1O4K 1O4L 1O4M 1O4N 1O4O 1O4P 1O4Q 1O4R 1SHD 1Y57 1YI6 1YOJ 1YOL 1YOM 2BDF 2BDJ 2H8H 2SRC 3VRO 3ZMP 3ZMQ 4F59 4F5A 4F5B 4HXJ 4K11 4MXO 4MXX 4MXY 4MXZ 6ATE 6C4S 6E6E 6EHJ	1BYQ 1OSF 1UY6 1UY7 1UY8 1UY9 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL 1YC1 1YC3 1YC4 1YER 1YES 1YET 2BSM 2BT0 2BUG 2BYH 2BYI 2BZ5 2C2L 2CCS 2CCT 2CCU 2FWY 2FWZ 2H55 2JJC 2K5B 2QF6 2QFO 2QG0 2QG2 2UWD 2VCI 2VCJ 2WI1 2WI2 2WI3 2WI4 2WI5 2WI6 2WI7 2XAB 2XDK 2XDL 2XDS 2XDU 2XDX 2XHR 2XHT 2XHX 2XJG 2XJJ 2XJX 2XK2 2YE2 2YE3 2YE4 2YE5 2YE6 2YE7 2YE8 2YE9 2YEA 2YEB 2YEC 2YED 2YEE 2YEF 2YEG 2YEH 2YEI 2YEJ 2YI0 2YI5 2YI6 2YI7 2YJW 2YJX 2YK2 2YK9 2YKB 2YKC 2YKE 2YKI 2YKJ 3B24 3B25 3B26 3B27 3B28 3BM9 3BMY 3D0B 3EKO 3EKR 3FT5 3FT8 3HEK 3HHU 3HYY 3HYZ 3HZ1 3HZ5 3INW 3INX 3K97 3K98 3K99 3MNR 3O0I 3OW6 3OWB 3OWD 3Q6M 3Q6N 3QDD 3QTF 3R4M 3R4N 3R4O 3R4P 3R91 3R92 3RKZ 3RLP 3RLQ 3RLR 3T0H 3T0Z 3T10 3T1K 3T2S 3TUH 3VHA 3VHC 3VHD 3WHA 3WQ9 4AIF 4AWO 4AWP 4AWQ 4B7P 4BQG 4BQJ 4CGQ 4CGU 4CGV 4CGW 4CWF 4CWN 4CWO 4CWP 4CWQ 4CWR 4CWS 4CWT 4EEH 4EFT 4EFU 4EGH 4EGI 4EGK 4FCP 4FCQ 4FCR 4HY6 4JQL 4L8Z 4L90 4L91 4L93 4L94 4LWE 4LWF 4LWG 4LWH 4LWI 4NH7 4NH8 4O04 4O05 4O07 4O09 4O0B 4R3M 4U93 4W7T 4XIP 4XIQ 4XIR 4XIT 4YKQ 4YKR 4YKT 4YKU 4YKW 4YKX 4YKY 4YKZ 5CF0 5FNC 5FND 5FNF 5GGZ 5J20 5J27 5J2V 5J2X 5J64 5J6L 5J6M 5J6N 5J80 5J82 5J86 5J8M 5J8U 5J9X 5LNY 5LNZ 5LO0 5LO1 5LO5 5LO6 5LQ9 5LR1 5LR7 5LRL 5LRZ 5LS1 5M4E 5M4H 5NYH 5NYI 5OCI 5OD7 5ODX 5T21 5VYY 5XQD 5XQE 5XR5 5XR9 5XRB 5XRD 5XRE 5ZR3 6B99 6B9A 6CEO 6CYG 6CYH 6EI5 6EL5 6ELN 6ELO 6ELP 6EY8 6EY9 6EYA 6EYB 6F1N 6FCJ 6FDP 6GP4 6GP8 6GPF 6GPH 6GPO 6GPP 6GPR 6GPT 6GPW 6GPY 6GQ6 6GQR 6GQS 6GQU 6GR1 6GR3 6GR4 6GR5 6HHR 6KSQ 6N8X 6OLX 6TN4 6TN5 6U98 6U99 6U9A 6U9B
Enriched GO Terms of Interacting Partners?
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