HSP90AA1 and AKT1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		HSP90AA1	AKT1
Description		heat shock protein 90 alpha family class A member 1	AKT serine/threonine kinase 1
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Protein-containing Complex Secretory Granule Lumen Melanosome Neuronal Cell Body Lysosomal Lumen Myelin Sheath Dendritic Growth Cone Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Exosome Endocytic Vesicle Lumen Ficolin-1-rich Granule Lumen	Nucleus Nucleoplasm Cytoplasm Mitochondrion Spindle Cytosol Plasma Membrane Cell-cell Junction Microtubule Cytoskeleton Lamellipodium Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Vesicle Protein-containing Complex Ciliary Basal Body Postsynapse
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity MHC Class II Protein Complex Binding Nitric-oxide Synthase Regulator Activity TPR Domain Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Protein Folding Chaperone Tau Protein Binding GTPase Binding Unfolded Protein Binding DNA Polymerase Binding Scaffold Protein Binding Disordered Domain Specific Binding Protein Tyrosine Kinase Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Kinase C Binding Protein Binding Calmodulin Binding ATP Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Kinase Activity Enzyme Binding Nitric-oxide Synthase Regulator Activity GTPase Activating Protein Binding Identical Protein Binding Protein Homodimerization Activity Phosphatidylinositol-3,4-bisphosphate Binding Protein Phosphatase 2A Binding 14-3-3 Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Protein Folding Mitochondrial Transport Receptor-mediated Endocytosis Response To Unfolded Protein Telomere Maintenance Via Telomerase Response To Heat Response To Cold Regulation Of G2/M Transition Of Mitotic Cell Cycle Viral Process Cytokine-mediated Signaling Pathway Central Nervous System Neuron Axonogenesis Establishment Of Cell Polarity Regulation Of Protein Ubiquitination Positive Regulation Of Protein Polymerization Positive Regulation Of Interferon-beta Production Positive Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Heat Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ERBB2 Signaling Pathway Protein Refolding Regulation Of Apoptotic Process Regulation Of Protein-containing Complex Assembly Neutrophil Degranulation Protein Unfolding Protein Insertion Into Mitochondrial Outer Membrane Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Antibiotic Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Extension Protein Stabilization Regulation Of Nitric-oxide Synthase Activity Chaperone-mediated Protein Complex Assembly Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Telomerase Activity Chaperone-mediated Autophagy Ciliary Basal Body-plasma Membrane Docking Cellular Response To Virus Regulation Of Cellular Response To Heat Positive Regulation Of Tau-protein Kinase Activity Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Cellular Protein Localization Telomerase Holoenzyme Complex Assembly	Osteoblast Differentiation Maternal Placenta Development Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Cell Migration Involved In Sprouting Angiogenesis Sphingosine-1-phosphate Receptor Signaling Pathway Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process Glucose Metabolic Process Translation Regulation Of Translation Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Protein Import Into Nucleus Nitric Oxide Biosynthetic Process Activation-induced Cell Death Of T Cells Inflammatory Response Cellular Response To DNA Damage Stimulus Response To Oxidative Stress Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Germ Cell Development Aging Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Apoptotic Mitochondrial Changes Carbohydrate Transport Response To Heat Negative Regulation Of Autophagy Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Fibroblast Migration Positive Regulation Of Fibroblast Migration Positive Regulation Of Sodium Ion Transport Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Endopeptidase Activity Regulation Of Neuron Projection Development Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Macroautophagy Phosphorylation Protein Ubiquitination Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Cytokine-mediated Signaling Pathway Spinal Cord Development Cell Projection Organization Cell Differentiation Protein Catabolic Process Hyaluronan Metabolic Process Positive Regulation Of Cell Growth Regulation Of Cell Migration Endocrine Pancreas Development T Cell Costimulation Negative Regulation Of Protein Ubiquitination Regulation Of Myelination Lipopolysaccharide-mediated Signaling Pathway TOR Signaling Negative Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Protein Binding Response To Food Activation Of Protein Kinase B Activity Positive Regulation Of Cellular Protein Metabolic Process Peripheral Nervous System Myelin Maintenance Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Insulin Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Response To Fluid Shear Stress Cellular Response To Reactive Oxygen Species Intracellular Signal Transduction Interleukin-18-mediated Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus NIK/NF-kappaB Signaling Glucose Homeostasis Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Anoikis Regulation Of MRNA Stability Protein Kinase B Signaling Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Cell Size Negative Regulation Of Proteolysis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Vasoconstriction Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Negative Regulation Of JNK Cascade Positive Regulation Of Organ Growth Protein Autophosphorylation Positive Regulation Of Lipid Biosynthetic Process Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of DNA-binding Transcription Factor Activity Striated Muscle Cell Differentiation Negative Regulation Of Protein Kinase B Signaling Excitatory Postsynaptic Potential Response To Growth Hormone Mammary Gland Epithelial Cell Differentiation Labyrinthine Layer Blood Vessel Development Response To UV-A Cellular Response To Mechanical Stimulus Cellular Response To Cadmium Ion Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Prostaglandin E Stimulus Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Negative Regulation Of Protein Serine/threonine Kinase Activity Establishment Of Protein Localization To Mitochondrion Maintenance Of Protein Location In Mitochondrion Negative Regulation Of Release Of Cytochrome C From Mitochondria Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Execution Phase Of Apoptosis Negative Regulation Of Protein Kinase Activity By Protein Phosphorylation Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Localization To Nucleus Negative Regulation Of Neuron Death Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of I-kappaB Phosphorylation Cellular Response To Nerve Growth Factor Stimulus Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Protein Localization To Cell Surface Negative Regulation Of Lymphocyte Migration Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Signaling by ERBB2 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation vRNP Assembly Regulation of actin dynamics for phagocytic cup formation eNOS activation Regulation of PLK1 Activity at G2/M Transition Scavenging by Class F Receptors Scavenging by Class F Receptors HSP90 chaperone cycle for steroid hormone receptors (SHR) HSF1 activation Attenuation phase HSF1-dependent transactivation Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Sema3A PAK dependent Axon repulsion VEGFA-VEGFR2 Pathway VEGFA-VEGFR2 Pathway VEGFR2 mediated vascular permeability Uptake and function of diphtheria toxin PIWI-interacting RNA (piRNA) biogenesis Anchoring of the basal body to the plasma membrane Constitutive Signaling by EGFRvIII Regulation of necroptotic cell death Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Downregulation of ERBB2 signaling ESR-mediated signaling Extra-nuclear estrogen signaling RHOBTB2 GTPase cycle Estrogen-dependent gene expression Chaperone Mediated Autophagy Constitutive Signaling by Overexpressed ERBB2 Aggrephagy Drug-mediated inhibition of ERBB2 signaling Signaling by ERBB2 KD Mutants Resistance of ERBB2 KD mutants to trastuzumab Resistance of ERBB2 KD mutants to sapitinib Resistance of ERBB2 KD mutants to tesevatinib Resistance of ERBB2 KD mutants to neratinib Resistance of ERBB2 KD mutants to osimertinib Resistance of ERBB2 KD mutants to afatinib Resistance of ERBB2 KD mutants to AEE788 Resistance of ERBB2 KD mutants to lapatinib Signaling by ERBB2 ECD mutants Signaling by ERBB2 TMD/JMD mutants Drug resistance in ERBB2 TMD/JMD mutants Potential therapeutics for SARS	Activation of BAD and translocation to mitochondria PIP3 activates AKT signaling PIP3 activates AKT signaling Downregulation of ERBB2:ERBB3 signaling Translocation of SLC2A4 (GLUT4) to the plasma membrane Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation MTOR signalling AKT phosphorylates targets in the cytosol AKT phosphorylates targets in the cytosol AKT phosphorylates targets in the nucleus Negative regulation of the PI3K/AKT network eNOS activation AKT-mediated inactivation of FOXO1A Integrin signaling Deactivation of the beta-catenin transactivating complex CD28 dependent PI3K/Akt signaling CTLA4 inhibitory signaling G beta:gamma signalling through PI3Kgamma Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA VEGFR2 mediated vascular permeability TP53 Regulates Metabolic Genes Constitutive Signaling by AKT1 E17K in Cancer Interleukin-4 and Interleukin-13 signaling Regulation of TP53 Degradation Regulation of TP53 Activity through Acetylation Regulation of TP53 Activity through Association with Co-factors PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Cyclin E associated events during G1/S transition Cyclin A:Cdk2-associated events at S phase entry PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 RAB GEFs exchange GTP for GDP on RABs RUNX2 regulates genes involved in cell migration Regulation of PTEN stability and activity Extra-nuclear estrogen signaling Negative regulation of NOTCH4 signaling FLT3 Signaling Regulation of localization of FOXO transcription factors Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs		Rifabutin Nedocromil 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine Geldanamycin 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine 4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine 9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine 4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine Quercetin 8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE Tanespimycin SNX-5422 N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE 2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE 3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol CCT-018159 4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine (5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- 4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol 2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine 4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine 3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE Copper Polaprezinc Alvespimycin	ATP Arsenic trioxide Genistein Inositol 1,3,4,5-Tetrakisphosphate Resveratrol Archexin Enzastaurin Perifosine N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
Diseases			PTEN hamartoma tumor syndrome (PHTS), including: Cowden syndrome; Bannayan-Riley-Ruvalcaba syndrome; Proteus syndrome; Proteus-like syndrome
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)	Apolipoprotein A1 levels ( 32203549) Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401) HDL cholesterol ( 24097068 30275531 25961943) HDL cholesterol levels ( 32203549 28334899) Neutrophil count ( 32888494)
Interacting Genes		158 interacting genes: AHR AHSA1 AHSA2P AIP AIPL1 AKT1 AKT2 APAF1 APOB AR ARNTL ASGR1 BIRC5 BRMS1 CACYBP CALM1 CDC37 CDC37L1 CDK4 CDK5R1 CDKN2A CERS2 CFTR CHEK1 CHORDC1 CHUK CKS1B CKS2 CRNKL1 CSNK2A1 CSNK2A2 DAP3 DNAJC7 EGFR EGLN1 EIF2AK1 EIF2AK2 EIF2AK3 EIF2S1 EPAS1 EPRS1 ERBB2 ERN1 ESR1 ESRRB FAM162A FANCA FANCC FKBP1A FKBP4 FKBP5 FKBP6 FLCN FNIP1 FYN GABARAPL1 GNA12 GSK3B GUCY1B1 GZMA HDAC6 HIF1A HIF3A HSF1 HSPA8 HTT IKBKB IKBKE IKBKG IP6K2 IRAK1 IRF3 ITGB1BP2 JUN KDR KEAP1 LCK LINC01554 LSM1 MAP3K14 MAP3K3 MAPK1 MAPT MIS12 MMP2 MS4A2 MTRNR2L1 MUC1 MYC MYOD1 NDRG1 NOS1 NOS3 NPAS2 NR2C2 NR3C1 NR3C2 NSL1 PABPN1 PAK1 PDPK1 PIM1 PMF1 PPARA PPARD PPID PPIL2 PPP5C PRKACA PRKCA PRKCD PRKDC PTGDS PTGES3 PTPRF RAD51 RAF1 RHOBTB2 RIPK1 RPAP3 RPS3 RPS3A RUNX1T1 SERPINB5 SGTA SIM1 SKP1 SLC2A4 SLC34A1 SMYD2 SMYD3 SNCA SRC ST13 STARD13 STAT3 STIP1 STUB1 SUGT1 SUMO2 SVIL TBK1 TERT TJP1 TNFRSF1A TOMM34 TOMM40 TOMM70 TP53 TTK TTR UBASH3A UBE2N UCHL1 UNC45A USP19 USP50 WASL	319 interacting genes: ACAP1 ACAT2 AGAP2 AGR3 AHNAK AHSA1 AKT1S1 AKT2 AKTIP ALYREF APLP2 APOH APP APPL1 AR ARAF ARFIP2 ARNT ATXN1 AURKA BABAM1 BAD BCL10 BCL2L1 BCL2L11 BCL3 BECN1 BEX1 BLVRA BPGM BRAF BRCA1 BUB1 CAMKK1 CARHSP1 CASC3 CASP3 CASP9 CBLC CCDC88A CCND2 CCNE1 CCNF CCNI CD44 CDC37 CDH1 CDK4 CDK6 CDKN1A CDKN1B CDKN1C CDKN2A CDKN2B CDKN2C CEP57L1 CEP76 CHEK1 CHUK CLASP2 CLIP3 CLK2 CNOT9 CREB1 CREBBP CSNK2A1 CTDSP2 CTNNA1 CTNNB1 CYLD DAB2IP DCTN1 DDIT4L DLC1 DNAJB1 DNMT1 EEF1G EIF4EBP1 EMSY ENO2 EP300 EPHA2 EPSTI1 ERBB2 ESR1 ESR2 EZH2 FAF1 FANCA FANCI FASN FBXO31 FBXW7 FGFR4 FOXO1 FOXO3 FOXO4 FUS FZR1 GAB2 GATA1 GATA2 GET4 GFAP GJA1 GLIS2 GRB10 GRIN2A GSK3A GSK3B H2BC21 H2BC3 HIF1A HMOX1 HSP90AA1 HSP90AB1 HSPB1 HTT IKBKB IL13RA2 IL24 ILK IMPDH2 IRAK1 IRS1 ITGB3 ITPR1 ITPR3 IWS1 JADE1 KANK1 KAT2A KAT2B KAT6A KDELR2 KLHL3 KMT2D KRT10 LANCL2 LATS2 LRRK2 LTB4R2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP3K11 MAP3K5 MAP3K8 MAPK14 MAPK8 MAPK8IP1 MAPK9 MAPKAP1 MAPKAPK2 MAPT MATK MDM2 MDM4 MESD METTL1 MLH3 MRC2 MS4A2 MSH2 MST1R MTA3 MTCP1 MTOR MTUS2 MUL1 MXD1 MYC NCF2 NCOA4 NCOR2 NF1 NF2 NGB NOL4 NOS3 NOTCH1 NR4A1 NRAS NSD3 OSGIN1 PAK1 PDE3A PDE3B PDGFRA PDHB PDK1 PDK2 PDPK1 PEA15 PFKFB1 PFKFB2 PFKP PHB2 PI4K2B PIAS1 PIAS2 PICK1 PIK3CA PIK3R1 PIP5K1C PKN2 PLCG1 PLEKHO1 PLP1 PLXNA1 PMS2 PPARGC1B PPL PPM1A PPP2CA PPP2R1A PRG2 PRKCQ PRKCZ PRKDC PSMC5 PTEN PTGDS PTPA PTPN1 PTPN11 PTPN3 PYGO2 RAB3D RAC1 RAF1 RARA RASL10B RASSF1 RGCC RHEBL1 RNF11 RNF115 RPS6KB1 S100A14 S1PR1 SERPINB5 SETDB1 SH2B2 SH3RF1 SIRPA SIRT1 SIRT6 SKI SKP2 SLC9A3R1 SMAD2 SMAD3 SMAD4 SMAD7 SMARCB1 SMARCC1 SNCA SNCB SORBS2 SOX2 SOX4 SP1 SP3 SRC SRPK2 SRR SSH1 ST14 STAT1 STK11 STK3 STK4 SULT4A1 SUPT6H SYTL1 TBC1D4 TBC1D7 TCL1A TCL1B TCL6 TEAD2 TERF2IP TERT TFF1 THEM4 THRSP TLR2 TMCC2 TNFRSF1A TNFSF11 TNK2 TOPBP1 TP53 TRIB3 TRIM13 TRMT2B TSC1 TSC2 TTC3 UBE2S UCHL1 USP4 UXS1 VEGFA VHL VIM WNK1 WNK4 XAF1 XIAP YAP1 YBX1 YWHAZ ZFP36L1 ZHX1 ZNF691 ZRANB1
Entrez ID		3320	207
HPRD ID		00777	01261
Ensembl ID		ENSG00000080824	ENSG00000142208
Uniprot IDs		K9JA46 P07900 Q86SX1	B0LPE5 B3KVH4 P31749
PDB IDs		1BYQ 1OSF 1UY6 1UY7 1UY8 1UY9 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL 1YC1 1YC3 1YC4 1YER 1YES 1YET 2BSM 2BT0 2BUG 2BYH 2BYI 2BZ5 2C2L 2CCS 2CCT 2CCU 2FWY 2FWZ 2H55 2JJC 2K5B 2QF6 2QFO 2QG0 2QG2 2UWD 2VCI 2VCJ 2WI1 2WI2 2WI3 2WI4 2WI5 2WI6 2WI7 2XAB 2XDK 2XDL 2XDS 2XDU 2XDX 2XHR 2XHT 2XHX 2XJG 2XJJ 2XJX 2XK2 2YE2 2YE3 2YE4 2YE5 2YE6 2YE7 2YE8 2YE9 2YEA 2YEB 2YEC 2YED 2YEE 2YEF 2YEG 2YEH 2YEI 2YEJ 2YI0 2YI5 2YI6 2YI7 2YJW 2YJX 2YK2 2YK9 2YKB 2YKC 2YKE 2YKI 2YKJ 3B24 3B25 3B26 3B27 3B28 3BM9 3BMY 3D0B 3EKO 3EKR 3FT5 3FT8 3HEK 3HHU 3HYY 3HYZ 3HZ1 3HZ5 3INW 3INX 3K97 3K98 3K99 3MNR 3O0I 3OW6 3OWB 3OWD 3Q6M 3Q6N 3QDD 3QTF 3R4M 3R4N 3R4O 3R4P 3R91 3R92 3RKZ 3RLP 3RLQ 3RLR 3T0H 3T0Z 3T10 3T1K 3T2S 3TUH 3VHA 3VHC 3VHD 3WHA 3WQ9 4AIF 4AWO 4AWP 4AWQ 4B7P 4BQG 4BQJ 4CGQ 4CGU 4CGV 4CGW 4CWF 4CWN 4CWO 4CWP 4CWQ 4CWR 4CWS 4CWT 4EEH 4EFT 4EFU 4EGH 4EGI 4EGK 4FCP 4FCQ 4FCR 4HY6 4JQL 4L8Z 4L90 4L91 4L93 4L94 4LWE 4LWF 4LWG 4LWH 4LWI 4NH7 4NH8 4O04 4O05 4O07 4O09 4O0B 4R3M 4U93 4W7T 4XIP 4XIQ 4XIR 4XIT 4YKQ 4YKR 4YKT 4YKU 4YKW 4YKX 4YKY 4YKZ 5CF0 5FNC 5FND 5FNF 5GGZ 5J20 5J27 5J2V 5J2X 5J64 5J6L 5J6M 5J6N 5J80 5J82 5J86 5J8M 5J8U 5J9X 5LNY 5LNZ 5LO0 5LO1 5LO5 5LO6 5LQ9 5LR1 5LR7 5LRL 5LRZ 5LS1 5M4E 5M4H 5NYH 5NYI 5OCI 5OD7 5ODX 5T21 5VYY 5XQD 5XQE 5XR5 5XR9 5XRB 5XRD 5XRE 5ZR3 6B99 6B9A 6CEO 6CYG 6CYH 6EI5 6EL5 6ELN 6ELO 6ELP 6EY8 6EY9 6EYA 6EYB 6F1N 6FCJ 6FDP 6GP4 6GP8 6GPF 6GPH 6GPO 6GPP 6GPR 6GPT 6GPW 6GPY 6GQ6 6GQR 6GQS 6GQU 6GR1 6GR3 6GR4 6GR5 6HHR 6KSQ 6N8X 6OLX 6TN4 6TN5 6U98 6U99 6U9A 6U9B	1H10 1UNP 1UNQ 1UNR 2UVM 2UZR 2UZS 3CQU 3CQW 3MV5 3MVH 3O96 3OCB 3OW4 3QKK 3QKL 3QKM 4EJN 4EKK 4EKL 4GV1 5KCV 6BUU 6CCY 6HHF 6HHG 6HHH 6HHI 6HHJ 6NPZ 6S9W 6S9X
Enriched GO Terms of Interacting Partners?
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