SLC14A1 and MIP

Data Source:
BioGRID (two hybrid)

		SLC14A1	MIP
Description		solute carrier family 14 member 1 (Kidd blood group)	major intrinsic protein of lens fiber
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Water Transmembrane Transporter Activity Urea Channel Activity	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity
	Biological Process	Water Transport Urea Transport Transmembrane Transport Urea Transmembrane Transport	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Transport of bile salts and organic acids, metal ions and amine compounds	Passive transport by Aquaporins
Drugs			B-nonylglucoside
Diseases
GWAS		Bladder cancer ( 21750109 21824976) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Pursuit maintenance gain ( 29064472) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)	Axial length ( 24144296)
Interacting Genes		11 interacting genes: BTN2A2 C1GALT1 FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE	47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1
Entrez ID		6563	4284
HPRD ID		00195	01098
Ensembl ID		ENSG00000141469	ENSG00000135517
Uniprot IDs		B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336	P30301
PDB IDs		6QD5
Enriched GO Terms of Interacting Partners?
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