SLC14A1 and THSD7B

Data Source:
BioGRID (two hybrid)

		SLC14A1	THSD7B
Description		solute carrier family 14 member 1 (Kidd blood group)	thrombospondin type 1 domain containing 7B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Water Transmembrane Transporter Activity Urea Channel Activity
	Biological Process	Water Transport Urea Transport Transmembrane Transport Urea Transmembrane Transport	Actin Cytoskeleton Reorganization
Pathways		Transport of bile salts and organic acids, metal ions and amine compounds	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Bladder cancer ( 21750109 21824976) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Pursuit maintenance gain ( 29064472) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)	Albumin-globulin ratio ( 29403010) Aluminium levels ( 26025379) Daytime sleep phenotypes ( 27126917) Liver enzyme levels (aspartate transaminase) ( 24124411) Machado-Joseph disease (age at onset) ( 32205469) Multiple system atrophy ( 27629089) Non-albumin protein levels ( 29403010) Non-small cell lung cancer ( 23144319) Pancreatic cancer ( 20686608) Problematic alcohol use ( 32451486) Prudent dietary pattern ( 28644415) Regular attendance at a gym or sports club ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcutaneous adipose tissue ( 22589738) Systolic blood pressure ( 30224653) Tooth agenesis (third molar) ( 24172245) Urinary albumin-to-creatinine ratio ( 26631737) Weight ( 28552196)
Interacting Genes		11 interacting genes: BTN2A2 C1GALT1 FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE	25 interacting genes: AQP6 ARL13B CISD2 DARS2 FAM209A FKBP7 GJA8 GPR101 GPR152 GPR37L1 KCNJ6 KIR3DL1 LYVE1 MFSD14B MTIF3 PEX12 PIGP PLEKHO1 RANBP10 SLC14A1 SLC30A8 SPACA1 STOM SYT2 TMX2
Entrez ID		6563	80731
HPRD ID		00195	19009
Ensembl ID		ENSG00000141469	ENSG00000144229
Uniprot IDs		B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336	Q9C0I4
PDB IDs		6QD5
Enriched GO Terms of Interacting Partners?
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