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SLC7A1 and TMBIM6
Data Source:
BioGRID
(two hybrid)
SLC7A1
TMBIM6
Description
solute carrier family 7 member 1
transmembrane BAX inhibitor motif containing 6
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Basal Plasma Membrane
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Protein-containing Complex
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Molecular Function
L-ornithine Transmembrane Transporter Activity
L-histidine Transmembrane Transporter Activity
Protein Binding
Amino Acid Transmembrane Transporter Activity
Basic Amino Acid Transmembrane Transporter Activity
Arginine Transmembrane Transporter Activity
L-lysine Transmembrane Transporter Activity
L-arginine Transmembrane Transporter Activity
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Endoribonuclease Inhibitor Activity
Biological Process
Amino Acid Transport
L-amino Acid Transport
Lysine Transport
Ornithine Transport
Positive Regulation Of T Cell Proliferation
Amino Acid Import Across Plasma Membrane
L-arginine Import Across Plasma Membrane
Transport Across Blood-brain Barrier
L-ornithine Transmembrane Transport
L-lysine Transmembrane Transport
L-histidine Import Across Plasma Membrane
Arginine Transmembrane Transport
Basic Amino Acid Transmembrane Transport
Negative Regulation Of Immunoglobulin Production
Autophagy
Negative Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of RNA Splicing
Cellular Response To Unfolded Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Endoribonuclease Activity
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Response To L-glutamate
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Amino acid transport across the plasma membrane
Drugs
L-Lysine
Arginine
Ornithine
Diseases
GWAS
Blood osmolality (transformed sodium) (
28360221
)
Diastolic blood pressure (
27841878
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Medication use (diuretics) (
31015401
)
Metabolite levels (
23823483
)
Systolic blood pressure (
27841878
30578418
)
General cognitive ability (
29844566
)
Interacting Genes
57 interacting genes:
ADGRB3
APOA2
APP
AQP6
ATP6V0C
C8A
CBLIF
CCL4
CCL4L2
CD40
CD79A
CDIPT
CERS4
CMTM2
COMT
CREB3L1
EMC6
FAM241B
FATE1
FCER1G
GALNT15
GET1
GLB1
GPR152
HERPUD2
LEPROT
LEPROTL1
LMNA
MFF
MGST3
MS4A13
NUCB2
ORMDL3
PDCD1LG2
PNLIPRP1
PSCA
PTPN9
RNF144A
SACM1L
SCN3B
SEC23A
SLC10A6
SLC18A2
SLC30A2
SLC39A2
SLC39A9
SLC52A1
SMCO4
ST6GAL2
STIM1
TMBIM6
TMEM14A
TMEM19
TMEM237
TRARG1
TSPO2
YIPF4
68 interacting genes:
ADIPOR2
ATP13A1
BCL2
BCL2L1
CD300LG
CD79A
CD99L2
CDC7
CERS2
CLDN22
COBLL1
CREB3L1
EBP
ENPP4
ERP29
ESAM
FAM209A
FERD3L
FGFBP2
FXYD3
GJA5
GJA8
GJB4
GLP1R
GPHB5
GPR151
GPR42
GPX8
GYPA
GZMK
HERPUD2
HJV
HTR2C
IER3
JSRP1
KCNA10
KCNC1
LIME1
LRRC59
MANBAL
MFSD14B
MMGT1
MS4A3
ODF4
OPRM1
PI16
PIANP
PVR
REEP2
RHBDL2
RNF185
SCN3B
SIT1
SLAMF6
SLC12A7
SLC41A3
SLC7A1
SOAT2
STEAP1B
SYT9
TEX29
TMEM31
TMUB1
TMX2
TNFRSF17
TREML1
UGT2B11
VTI1A
Entrez ID
6541
7009
HPRD ID
00091
02851
Ensembl ID
ENSG00000139514
ENSG00000139644
Uniprot IDs
A0A024RDQ9
P30825
A0A024R0Z5
P55061
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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