SLC13A3 and CISD2

Data Source:
BioGRID (two hybrid)

		SLC13A3	CISD2
Description		solute carrier family 13 member 3	CDGSH iron sulfur domain 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Extracellular Exosome	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum
	Molecular Function	Dicarboxylic Acid Transmembrane Transporter Activity Protein Binding Citrate Transmembrane Transporter Activity Alpha-ketoglutarate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity High-affinity Sodium:dicarboxylate Symporter Activity Sodium:dicarboxylate Symporter Activity Glutathione Transmembrane Transporter Activity	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Sodium Ion Transport Dicarboxylic Acid Transport Alpha-ketoglutarate Transport Citrate Transport Glutathione Transmembrane Transport Succinate Transmembrane Transport Anion Transmembrane Transport Transport Across Blood-brain Barrier	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways		Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases			Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Brain volume in infants (white matter) ( 28763065) Chronic kidney disease ( 24351856) Glomerular filtration rate ( 24351856) Gout ( 22179738) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		10 interacting genes: ARL13B CISD2 CREB3L1 CYB5R3 ERGIC3 FAM209A GPX8 LEUTX LMNA RMDN3	58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6
Entrez ID		64849	493856
HPRD ID		10450	17413
Ensembl ID		ENSG00000158296	ENSG00000145354
Uniprot IDs		B4DF27 Q8WWT9	Q8N5K1
PDB IDs			3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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