Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
MICAL1 and RPS6KA6
Data Source:
BioGRID
(two hybrid)
MICAL1
RPS6KA6
Description
microtubule associated monooxygenase, calponin and LIM domain containing 1
ribosomal protein S6 kinase A6
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Intermediate Filament
Plasma Membrane
Actin Cytoskeleton
Midbody
Intercellular Bridge
Hippocampal Mossy Fiber Expansion
Fibrillar Center
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Cytosol
Molecular Function
Actin Binding
Protein Binding
NAD(P)H Oxidase H2O2-forming Activity
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen
SH3 Domain Binding
Protein Kinase Binding
Small GTPase Binding
Metal Ion Binding
Actin Filament Binding
FAD Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Ribosomal Protein S6 Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Negative Regulation Of Protein Phosphorylation
Cytoskeleton Organization
Signal Transduction
Blood Coagulation
Sulfur Oxidation
Actin Filament Depolymerization
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Actin Filament Bundle Assembly
Regulation Of Regulated Secretory Pathway
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Signal Transduction
Central Nervous System Development
Peptidyl-serine Phosphorylation
Negative Regulation Of Embryonic Development
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Mesoderm Development
Pathways
Factors involved in megakaryocyte development and platelet production
Recycling pathway of L1
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
RSK activation
RSK activation
Drugs
Fostamatinib
Diseases
GWAS
Depression in smokers (
30219690
)
Height (
28552196
)
Interacting Genes
16 interacting genes:
ABL1
CRK
EHD1
GADD45A
GRB2
GSK3B
NEDD9
PIK3R3
PTK2
RAB10
RAB1A
RAB1B
RPS6KA6
SRC
TAB1
VIM
28 interacting genes:
ADIRF
APP
CEBPZ
CENPB
CLEC3B
DHX34
DNAJC13
DNMT1
ERG28
FBN3
FZD5
LMO4
MASP1
MED24
MICAL1
MPP1
NR4A1
RBPJ
RPLP1
RXRA
SAP30BP
SPRED2
SPTBN4
SYNE4
UBE2I
UFM1
ZNF227
ZNF746
Entrez ID
64780
27330
HPRD ID
06183
02250
Ensembl ID
ENSG00000135596
ENSG00000072133
Uniprot IDs
Q8TDZ2
Q9UK32
PDB IDs
1WYL
2CO8
2DK9
5LE0
5LPN
6KU0
6G76
6G77
6G78
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?