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RPS6KA6 and CENPB
Data Source:
BioGRID
(two hybrid)
RPS6KA6
CENPB
Description
ribosomal protein S6 kinase A6
centromere protein B
Image
GO Annotations
Cellular Component
Fibrillar Center
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Cytosol
Chromosome, Centromeric Region
Condensed Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Chromosome
Pericentric Heterochromatin
Nuclear Body
Molecular Function
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Ribosomal Protein S6 Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
DNA Binding
Chromatin Binding
Satellite DNA Binding
Centromeric DNA Binding
Sequence-specific DNA Binding
Biological Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Signal Transduction
Central Nervous System Development
Peptidyl-serine Phosphorylation
Negative Regulation Of Embryonic Development
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Mesoderm Development
Pathways
Recycling pathway of L1
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
RSK activation
RSK activation
Drugs
Fostamatinib
Diseases
GWAS
Interacting Genes
28 interacting genes:
ADIRF
APP
CEBPZ
CENPB
CLEC3B
DHX34
DNAJC13
DNMT1
ERG28
FBN3
FZD5
LMO4
MASP1
MED24
MICAL1
MPP1
NR4A1
RBPJ
RPLP1
RXRA
SAP30BP
SPRED2
SPTBN4
SYNE4
UBE2I
UFM1
ZNF227
ZNF746
20 interacting genes:
ADRB2
ANXA7
APP
CDKN1A
CENPW
CSNK2B
FBXO25
GADD45A
GFI1B
GSK3B
HAND2
NR3C1
PARP1
PARP2
PIN1
RPS6KA6
SH2D3A
SMN1
TAC1
TK1
Entrez ID
27330
1059
HPRD ID
02250
00314
Ensembl ID
ENSG00000072133
ENSG00000125817
Uniprot IDs
Q9UK32
P07199
PDB IDs
6G76
6G77
6G78
1BW6
1HLV
1UFI
6KDR
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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