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MICAL1

Description microtubule associated monooxygenase, calponin and LIM domain containing 1
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Intermediate Filament
  • Plasma Membrane
  • Actin Cytoskeleton
  • Midbody
  • Intercellular Bridge
  • Hippocampal Mossy Fiber Expansion
Molecular Function
  • Actin Binding
  • Protein Binding
  • NAD(P)H Oxidase H2O2-forming Activity
  • Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen
  • SH3 Domain Binding
  • Protein Kinase Binding
  • Small GTPase Binding
  • Metal Ion Binding
  • Actin Filament Binding
  • FAD Binding
Biological Process
  • Negative Regulation Of Protein Phosphorylation
  • Cytoskeleton Organization
  • Signal Transduction
  • Blood Coagulation
  • Sulfur Oxidation
  • Actin Filament Depolymerization
  • Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
  • Actin Filament Bundle Assembly
  • Regulation Of Regulated Secretory Pathway
Pathways
  • Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
  • Depression in smokers ( 30219690)
  • Height ( 28552196)
Novel Interacting Genes 1 novel interacting genes: DNAH5
Interacting Genes 16 interacting genes: ABL1 CRK EHD1 GADD45A GRB2 GSK3B NEDD9 PIK3R3 PTK2 RAB10 RAB1A RAB1B RPS6KA6 SRC TAB1 VIM
Entrez ID 64780
HPRD ID 06183
Ensembl ID ENSG00000135596
Uniprot IDs Q8TDZ2
PDB IDs 1WYL 2CO8 2DK9 5LE0 5LPN 6KU0
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025