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SFTPC and CXCL9
Data Source:
BioGRID
(two hybrid, two hybrid)
SFTPC
CXCL9
Description
surfactant protein C
C-X-C motif chemokine ligand 9
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Membrane
Lamellar Body
Clathrin-coated Endocytic Vesicle
Alveolar Lamellar Body
Multivesicular Body Lumen
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Molecular Function
Protein Binding
Identical Protein Binding
Cytokine Activity
Protein Binding
Chemokine Activity
CXCR Chemokine Receptor Binding
CXCR3 Chemokine Receptor Binding
Biological Process
Respiratory Gaseous Exchange By Respiratory System
Cellular Protein Metabolic Process
Chemotaxis
Defense Response
Inflammatory Response
Cellular Defense Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Neutrophil Chemotaxis
Regulation Of Cell Population Proliferation
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Defense Response To Virus
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Positive Regulation Of Myoblast Fusion
Pathways
Surfactant metabolism
Defective pro-SFTPC causes SMDP2 and RDS
Defective CSF2RB causes SMDP5
Defective CSF2RA causes SMDP4
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Diseases
Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS
Coronary artery disease (
29212778
)
Hypertriglyceridemia (
23505323
)
Blood protein levels (
28240269
)
Hippocampal volume (
29274321
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Interacting Genes
36 interacting genes:
BSCL2
CD200R1
CD79A
CLDN5
CPLX4
CREB3
CXCL9
FAM209A
FNDC9
GJA8
GOLM1
GPR152
GPX8
HPN
ICAM3
IFNGR2
KLRC1
LMNA
LSMEM2
MUC1
NEDD4
PDZK1IP1
PQBP1
PVR
SEC22A
SEC61G
SIGLEC9
SMIM3
SYNE4
TMEM106C
TMEM139
TMEM30B
TMEM79
TMPRSS2
WWP1
WWP2
76 interacting genes:
AMIGO1
AQP6
ATP1B4
BMF
BSCL2
BTNL9
C16orf92
CCL11
CCL13
CCL2
CCL21
CCL26
CCL28
CCL5
CCR3
CD33
CHODL
CLDN2
CLDN5
CLDN7
CLEC17A
CLEC2D
CLEC4E
CLEC7A
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCR3
DPP4
EPGN
EREG
FBXO7
FCGR2A
FFAR2
FNDC9
FUT7
GJB1
GORAB
GPR42
IFNGR2
ITM2C
KASH5
KIR2DL3
LDLRAD1
LEUTX
LRRC25
LSMEM2
MR1
MTIF3
MUC1
NEMP1
PAX8
PF4
PPBP
PTPN5
RHCG
SFTPC
SLC10A1
SLC39A1
SSMEM1
SUSD3
SYNE4
TM4SF18
TMED5
TMEM106C
TMEM234
TMEM237
TMEM31
TMPRSS2
TNFSF14
TNFSF8
TSPAN18
XCL1
Entrez ID
6440
4283
HPRD ID
01520
03416
Ensembl ID
ENSG00000168484
ENSG00000138755
Uniprot IDs
A0A0A0MTC9
A0A0S2Z4Q0
E5RI64
P11686
Q07325
PDB IDs
2YAD
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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