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SFTPC and FNDC9
Data Source:
BioGRID
(two hybrid)
SFTPC
FNDC9
Description
surfactant protein C
fibronectin type III domain containing 9
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Membrane
Lamellar Body
Clathrin-coated Endocytic Vesicle
Alveolar Lamellar Body
Multivesicular Body Lumen
Integral Component Of Membrane
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Respiratory Gaseous Exchange By Respiratory System
Cellular Protein Metabolic Process
Pathways
Surfactant metabolism
Defective pro-SFTPC causes SMDP2 and RDS
Defective CSF2RB causes SMDP5
Defective CSF2RA causes SMDP4
Drugs
Diseases
Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS
Coronary artery disease (
29212778
)
Hypertriglyceridemia (
23505323
)
Asthma (
31959851
)
Interacting Genes
36 interacting genes:
BSCL2
CD200R1
CD79A
CLDN5
CPLX4
CREB3
CXCL9
FAM209A
FNDC9
GJA8
GOLM1
GPR152
GPX8
HPN
ICAM3
IFNGR2
KLRC1
LMNA
LSMEM2
MUC1
NEDD4
PDZK1IP1
PQBP1
PVR
SEC22A
SEC61G
SIGLEC9
SMIM3
SYNE4
TMEM106C
TMEM139
TMEM30B
TMEM79
TMPRSS2
WWP1
WWP2
88 interacting genes:
ADIPOQ
AGTRAP
AIG1
AOC3
AQP1
ASGR1
ATXN1
BMP10
C1QL4
C3orf52
CLDN1
CLDN11
CLDN19
CLEC1A
CLEC2D
CLEC7A
CLN6
CLRN2
CMTM5
CNIH3
COL8A2
CTSA
CXCL16
CXCL9
CYB5B
DEFB132
DOLK
EDDM3B
EMP3
ENTPD3
ERMP1
EXTL1
GALNT15
GCNT2
HHATL
IGFBP5
ITM2A
ITM2C
JAGN1
KRTCAP3
LHFPL5
LPAR3
MAL
MALL
MOSPD3
NINJ1
NINJ2
NKG7
NSG1
OLFM4
PGA4
PGAP2
PLLP
PLN
PLP1
PLP2
PLPP6
PROKR2
RPRM
SEC22B
SERP2
SFTPC
SLC35A1
SLC41A2
SMIM1
SMIM3
ST6GAL2
STX8
TMEM100
TMEM140
TMEM182
TMEM254
TMEM60
TMEM79
TMEM86A
TMPRSS4
TNF
TRARG1
TREX1
TSPO2
TWSG1
UBIAD1
UPK1B
UPK2
VAMP5
VSTM1
ZDHHC22
ZFPL1
Entrez ID
6440
408263
HPRD ID
01520
17524
Ensembl ID
ENSG00000168484
ENSG00000172568
Uniprot IDs
A0A0A0MTC9
A0A0S2Z4Q0
E5RI64
P11686
Q8TBE3
PDB IDs
2YAD
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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