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FNDC9 and CLEC7A
Data Source:
BioGRID
(two hybrid)
FNDC9
CLEC7A
Description
fibronectin type III domain containing 9
C-type lectin domain containing 7A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Protein Binding
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Biological Process
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Phagocytosis
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Pathways
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Asthma (
31959851
)
Interacting Genes
88 interacting genes:
ADIPOQ
AGTRAP
AIG1
AOC3
AQP1
ASGR1
ATXN1
BMP10
C1QL4
C3orf52
CLDN1
CLDN11
CLDN19
CLEC1A
CLEC2D
CLEC7A
CLN6
CLRN2
CMTM5
CNIH3
COL8A2
CTSA
CXCL16
CXCL9
CYB5B
DEFB132
DOLK
EDDM3B
EMP3
ENTPD3
ERMP1
EXTL1
GALNT15
GCNT2
HHATL
IGFBP5
ITM2A
ITM2C
JAGN1
KRTCAP3
LHFPL5
LPAR3
MAL
MALL
MOSPD3
NINJ1
NINJ2
NKG7
NSG1
OLFM4
PGA4
PGAP2
PLLP
PLN
PLP1
PLP2
PLPP6
PROKR2
RPRM
SEC22B
SERP2
SFTPC
SLC35A1
SLC41A2
SMIM1
SMIM3
ST6GAL2
STX8
TMEM100
TMEM140
TMEM182
TMEM254
TMEM60
TMEM79
TMEM86A
TMPRSS4
TNF
TRARG1
TREX1
TSPO2
TWSG1
UBIAD1
UPK1B
UPK2
VAMP5
VSTM1
ZDHHC22
ZFPL1
47 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
Entrez ID
408263
64581
HPRD ID
17524
08396
Ensembl ID
ENSG00000172568
ENSG00000172243
Uniprot IDs
Q8TBE3
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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