FNDC9 and LPAR3

Data Source:
BioGRID (two hybrid)

		FNDC9	LPAR3
Description		fibronectin type III domain containing 9	lysophosphatidic acid receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Synapse
	Molecular Function	Protein Binding	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process		Activation Of MAPK Activity G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemical Synaptic Transmission Regulation Of Metabolic Process Bleb Assembly Positive Regulation Of Collateral Sprouting Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Calcium Ion Transport
Pathways			G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Asthma ( 31959851)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Dental caries ( 23064961) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		88 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 AQP1 ASGR1 ATXN1 BMP10 C1QL4 C3orf52 CLDN1 CLDN11 CLDN19 CLEC1A CLEC2D CLEC7A CLN6 CLRN2 CMTM5 CNIH3 COL8A2 CTSA CXCL16 CXCL9 CYB5B DEFB132 DOLK EDDM3B EMP3 ENTPD3 ERMP1 EXTL1 GALNT15 GCNT2 HHATL IGFBP5 ITM2A ITM2C JAGN1 KRTCAP3 LHFPL5 LPAR3 MAL MALL MOSPD3 NINJ1 NINJ2 NKG7 NSG1 OLFM4 PGA4 PGAP2 PLLP PLN PLP1 PLP2 PLPP6 PROKR2 RPRM SEC22B SERP2 SFTPC SLC35A1 SLC41A2 SMIM1 SMIM3 ST6GAL2 STX8 TMEM100 TMEM140 TMEM182 TMEM254 TMEM60 TMEM79 TMEM86A TMPRSS4 TNF TRARG1 TREX1 TSPO2 TWSG1 UBIAD1 UPK1B UPK2 VAMP5 VSTM1 ZDHHC22 ZFPL1	58 interacting genes: APP AQP6 ARL13B ASZ1 BCL2L13 C16orf54 CD53 CD74 CD79A CLDN2 CLDN7 CLDN9 CLEC12B CPLX4 CREB3L1 CYB561 CYBRD1 EDA ERGIC3 FAM209A FAM210B FFAR2 FNDC9 GJB5 GNAI2 GORAB GPX8 JAGN1 KCNC1 KCNJ6 LEPROTL1 LHFPL5 LIME1 LMNA MFF MGST3 MRM1 MS4A4A NDUFAF2 OPRM1 PGRMC2 RELL2 RETREG3 SCN3B SGMS2 SHISAL1 SLC10A6 SLC16A2 SLC35C2 TFEC THAP4 TMEM14B TMEM237 TMEM31 TMEM41A TMEM52B TMEM70 TMEM79
Entrez ID		408263	23566
HPRD ID		17524	05486
Ensembl ID		ENSG00000172568	ENSG00000171517
Uniprot IDs		Q8TBE3	Q9UBY5
PDB IDs
Enriched GO Terms of Interacting Partners?
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