PALS1 and CRB3

Data Source:
HPRD (in vitro, in vivo)

		PALS1	CRB3
Description		protein associated with LIN7 1, MAGUK family member	crumbs cell polarity complex component 3
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Apical Plasma Membrane Axon Protein-containing Complex Myelin Sheath Adaxonal Region Perikaryon Lateral Loop Schmidt-Lanterman Incisure Extracellular Exosome	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Protein Domain Specific Binding	Protein Binding SH3 Domain Binding Protein Domain Specific Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Gene Expression Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Central Nervous System Neuron Development Cerebral Cortex Development Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane	Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Positive Regulation Of Cell Junction Assembly
Pathways		Tight junction interactions	Tight junction interactions
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: ARF6 BHLHB9 CRB3 DLGAP4 FTCD LIN7A LIN7B LIN7C MPP4 NUMB PARD6B PATJ SNTG2 SOCS4 SRGAP2B TRAF2	28 interacting genes: ANKRD46 BCL2L13 BET1 FUNDC2 HMOX1 HMOX2 NDUFA3 PALS1 PARD6A PATJ PLLP PLP2 PSENEN PSMA3 RABAC1 SERF1A SERF1B SERP1 SLC39A9 STX5 TECR TMEM222 TREX1 UBIAD1 VAMP1 VTI1B WDR83 YIPF6
Entrez ID		64398	92359
HPRD ID		09508	16749
Ensembl ID		ENSG00000072415	ENSG00000130545
Uniprot IDs		Q658X5 Q8N3R9	Q9BUF7
PDB IDs		1Y76 3UIT 4UU5 4UU6 4WSI	5I7Z
Enriched GO Terms of Interacting Partners?
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