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PALS1 and SOCS4
Data Source:
BioGRID
(two hybrid)
PALS1
SOCS4
Description
protein associated with LIN7 1, MAGUK family member
suppressor of cytokine signaling 4
Image
GO Annotations
Cellular Component
Cytoplasm
Endoplasmic Reticulum-Golgi Intermediate Compartment
Golgi Apparatus
Plasma Membrane
Adherens Junction
Bicellular Tight Junction
Apical Plasma Membrane
Axon
Protein-containing Complex
Myelin Sheath Adaxonal Region
Perikaryon
Lateral Loop
Schmidt-Lanterman Incisure
Extracellular Exosome
Phosphatidylinositol 3-kinase Complex
Molecular Function
Protein Binding
ATP Binding
Protein Domain Specific Binding
Protein Binding
1-phosphatidylinositol-3-kinase Regulator Activity
Biological Process
Morphogenesis Of An Epithelial Sheet
Gene Expression
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Central Nervous System Neuron Development
Cerebral Cortex Development
Peripheral Nervous System Myelin Maintenance
Myelin Assembly
Protein Localization To Myelin Sheath Abaxonal Region
Bicellular Tight Junction Assembly
Protein Localization To Plasma Membrane
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Intracellular Signal Transduction
Regulation Of Growth
Regulation Of Phosphatidylinositol 3-kinase Activity
Phosphatidylinositol Phosphorylation
Pathways
Tight junction interactions
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs
Diseases
GWAS
Interacting Genes
16 interacting genes:
ARF6
BHLHB9
CRB3
DLGAP4
FTCD
LIN7A
LIN7B
LIN7C
MPP4
NUMB
PARD6B
PATJ
SNTG2
SOCS4
SRGAP2B
TRAF2
11 interacting genes:
CNMD
EGFR
LDHAL6B
MDFIC
NR4A1
PALS1
PLPP6
SPRY1
TEKT4
TNK2
VWF
Entrez ID
64398
122809
HPRD ID
09508
18084
Ensembl ID
ENSG00000072415
ENSG00000180008
Uniprot IDs
Q658X5
Q8N3R9
Q5H9R6
Q8WXH5
PDB IDs
1Y76
3UIT
4UU5
4UU6
4WSI
2IZV
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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