PALS1 and LIN7B

Data Source:
BioGRID (two hybrid)

		PALS1	LIN7B
Description		protein associated with LIN7 1, MAGUK family member	lin-7 homolog B, crumbs cell polarity complex component
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Apical Plasma Membrane Axon Protein-containing Complex Myelin Sheath Adaxonal Region Perikaryon Lateral Loop Schmidt-Lanterman Incisure Extracellular Exosome	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding ATP Binding Protein Domain Specific Binding	Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Gene Expression Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Central Nervous System Neuron Development Cerebral Cortex Development Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane
Pathways		Tight junction interactions	Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: ARF6 BHLHB9 CRB3 DLGAP4 FTCD LIN7A LIN7B LIN7C MPP4 NUMB PARD6B PATJ SNTG2 SOCS4 SRGAP2B TRAF2	22 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 ENKD1 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4 MAK16 MPP2 MPP3 MPP7 NTAQ1 PALS1 PALS2 PSMB1 TCEANC TRAPPC12
Entrez ID		64398	64130
HPRD ID		09508	10040
Ensembl ID		ENSG00000072415	ENSG00000104863
Uniprot IDs		Q658X5 Q8N3R9	Q9HAP6
PDB IDs		1Y76 3UIT 4UU5 4UU6 4WSI	2DKR
Enriched GO Terms of Interacting Partners?
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