NAPB and PLEKHO1

Data Source:
BioGRID (two hybrid)

		NAPB	PLEKHO1
Description		NSF attachment protein beta	pleckstrin homology domain containing O1
Image		No pdb structure
GO Annotations	Cellular Component	Vacuolar Membrane SNARE Complex Synapse Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane
	Molecular Function	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Regulation Of Synaptic Vesicle Priming Synaptic Transmission, Glutamatergic SNARE Complex Disassembly	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis
Pathways		COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Factor VII activity ( 30642921)	Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		31 interacting genes: ALOX5AP ARL6IP1 BET1 CISD2 CLEC10A CREB3L1 DGAT2L6 FAM209A GJB5 HSD17B13 KCNN3 LEUTX PLEKHO1 SDCBP SIGLEC5 SNAP23 SNAP29 STX16 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 SYT1 SYT2 TAF1B TFEC TMEM139	32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1
Entrez ID		63908	51177
HPRD ID		17627	12217
Ensembl ID		ENSG00000125814	ENSG00000023902
Uniprot IDs		A0A087WZQ7 Q9H115	Q53GL0 Q5T4P9
PDB IDs			3AA1
Enriched GO Terms of Interacting Partners?
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