PLEKHO1 and TRAF3IP3

Data Source:
BioGRID (two hybrid)

		PLEKHO1	TRAF3IP3
Description		pleckstrin homology domain containing O1	TRAF3 interacting protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Golgi Membrane Mitochondrial Outer Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Alopecia areata ( 25608926) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Orofacial clefts ( 33137956) Red blood cell count ( 32888494 27863252) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	47 interacting genes: ATG16L1 CBARP CCDC136 CCDC138 CCDC88B CCNC CDCA7L CEP68 CEP70 COQ9 CPLX4 CREB3L3 EBAG9 EMD EVI2B FAM209A FATE1 GOLGA6L9 GOLM2 GORAB GRAMD2A KASH5 KIR2DL3 KRT27 L3MBTL3 LIME1 LRRC25 MFF MINAR1 NDEL1 OSBPL3 PLEKHO1 PSTPIP1 RACGAP1 RIC3 RILPL1 SP100 STMN4 STX1A STX4 TFIP11 TMEM139 TRAF3 TRIM36 WAC ZNRD2 ZRANB1
Entrez ID		51177	80342
HPRD ID		12217	16305
Ensembl ID		ENSG00000023902	ENSG00000009790
Uniprot IDs		Q53GL0 Q5T4P9	B1AJU2 B3KWQ9 Q9Y228
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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