PLEKHO1 and CEP19

Data Source:
BioGRID (two hybrid)

		PLEKHO1	CEP19
Description		pleckstrin homology domain containing O1	centrosomal protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Spindle Pole Cytoplasm Centrosome Centriole Cilium Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis	Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738)
Interacting Genes		32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	50 interacting genes: AK4 ANAPC15 C4orf19 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CEP350 CEP43 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2A RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81
Entrez ID		51177	84984
HPRD ID		12217	17488
Ensembl ID		ENSG00000023902	ENSG00000174007
Uniprot IDs		Q53GL0 Q5T4P9	Q96LK0
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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