NAPB and SIGLEC5

Data Source:
BioGRID (two hybrid)

		NAPB	SIGLEC5
Description		NSF attachment protein beta	sialic acid binding Ig like lectin 5
Image		No pdb structure
GO Annotations	Cellular Component	Vacuolar Membrane SNARE Complex Synapse Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome	Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding	Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Intracellular Protein Transport Regulation Of Synaptic Vesicle Priming Synaptic Transmission, Glutamatergic SNARE Complex Disassembly	Cell Adhesion Neutrophil Degranulation
Pathways		COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Factor VII activity ( 30642921)	Aggressive periodontitis ( 28449029) Blood protein levels ( 29875488 28240269) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Leprosy ( 25642632) Lymphocyte counts ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Periodontitis ( 30218097) Platelet distribution width ( 32888494)
Interacting Genes		31 interacting genes: ALOX5AP ARL6IP1 BET1 CISD2 CLEC10A CREB3L1 DGAT2L6 FAM209A GJB5 HSD17B13 KCNN3 LEUTX PLEKHO1 SDCBP SIGLEC5 SNAP23 SNAP29 STX16 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 SYT1 SYT2 TAF1B TFEC TMEM139	5 interacting genes: LGALS3BP NAPB SLC7A8 TRIP13 VAC14
Entrez ID		63908	8778
HPRD ID		17627	05011
Ensembl ID		ENSG00000125814	ENSG00000105501
Uniprot IDs		A0A087WZQ7 Q9H115	O15389
PDB IDs			2ZG1 2ZG2 2ZG3
Enriched GO Terms of Interacting Partners?
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