RORB and ZNF417

Data Source:
BioGRID (two hybrid)

		RORB	ZNF417
Description		RAR related orphan receptor B	zinc finger protein 417
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Melatonin Receptor Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter G Protein-coupled Receptor Signaling Pathway Visual Perception Intracellular Receptor Signaling Pathway Amacrine Cell Differentiation Eye Photoreceptor Cell Development Regulation Of Circadian Rhythm Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Retinal Rod Cell Development Retinal Cone Cell Development Rhythmic Process Retina Development In Camera-type Eye Cellular Response To Retinoic Acid	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Alcohol consumption (drinks per week) ( 30643258) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Chronotype ( 30696823) Immature fraction of reticulocytes ( 32888494) Macular thickness ( 30535121) Refractive error ( 23396134 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Depression in smokers ( 30219690)
Interacting Genes		36 interacting genes: ANKS1A CLOCK CRACR2A CSNK2B DELEC1 FBXO7 GAS2L2 KRTAP4-5 LCK LCOR MAP6 MED25 MID2 NCOA1 NCOA6 NME1 NME2 NPPA NRIP1 NRIP2 NSD1 PNRC1 PNRC2 PSMC4 PSMC5 RORC SCNM1 SMARCD1 SOGA1 TEKT5 TLE5 TNNI2 TSGA10IP UBE2I ZNF417 ZNF587	169 interacting genes: ADAMTSL4 AXIN2 BEGAIN BEND5 BEX3 BHLHB9 BICD2 C4orf17 CARD9 CBY2 CCDC125 CCDC136 CCDC57 CCDC85B CCNDBP1 CDR2 CDR2L CEP44 CEP70 CEP72 CEP85L CHRDL2 COG6 CSRNP1 CYSRT1 DEF8 DVL3 EFS EZHIP FAM221A FHL2 FHL3 FHL5 FRS3 FSD2 FXR1 GOLGA2 GOLGA6L9 HMBOX1 HOMEZ HOOK2 HOXA1 HSF2BP IGFBP6 IHO1 IKZF1 INKA1 JADE2 JRK KAT5 KATNBL1 KCTD7 KIF9 KIFC3 KLC3 KRT15 KRT31 KRT35 KRT38 KRT39 KRT40 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LHX3 LIMS1 LMO1 LURAP1 LZTS1 LZTS2 MAGEA8 MAST2 MCC MCCD1 MDFI MEIS3 MEOX2 MID2 MIIP MRFAP1L1 MTUS2 MYF5 MYLIP NAB2 NBPF19 NDEL1 NDUFB7 NINL NKAPL NKX3-1 NOTCH2NLA OIP5 PHC2 PICK1 PIH1D2 PLSCR1 PNMA2 PRICKLE4 PRPF31 RCN3 REL RHOQ RNF187 RORB RPGRIP1 RUNDC3A SH2B2 SMARCD1 SMYD5 SPRED1 SPRED2 SPRY1 SPRY2 SSX2IP STX11 SUV39H1 TADA2A TCF4 TEKT4 TFIP11 TLE5 TMCC2 TNS2 TRAF1 TRAF2 TRIB3 TRIM23 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSC1 TSGA10 TXNDC11 U2AF1 U2AF1L5 USHBP1 VPS16 VPS52 VWC2 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZBTB9 ZNF165 ZNF19 ZNF20 ZNF547 ZNF572 ZNF587 ZNF69 ZNF71 ZNF768 ZNF774 ZNF837 ZNF85 ZRANB1
Entrez ID		6096	147687
HPRD ID		09062	18341
Ensembl ID		ENSG00000198963	ENSG00000173480
Uniprot IDs		Q58EY0	M0R230 Q8TAU3
PDB IDs
Enriched GO Terms of Interacting Partners?
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